Non-Hodgkin Lymphoma Pipeline Therapeutics Assessment Report 2024 (Updated)

DelveInsight's, "Non-Hodgkin Lymphoma Pipeline Insight" report provides comprehensive insights about 200+ companies and 220+ pipeline drugs in the Non-Hodgkin Lymphoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Explore our latest breakthroughs in Non-Hodgkin Lymphoma Research. Learn more about our innovative pipeline today! @ Non-Hodgkin Lymphoma Pipeline Outlook- https://www.delveinsight.com/sample-request/non-hodgkins-lymphoma-nhl-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the Non-Hodgkin Lymphoma Pipeline Report
• In December 2024:- AstraZeneca- This study is designed to evaluate the safety, tolerability, PK and preliminary efficacy following oral administration of AZD3470 as a monotherapy, and in combination with other anticancer agents in participants with haematologic malignancies.
• In December 2024:- Genmab- The purpose of this trial is to evaluate the safety, tolerability, immunogenicity, pharmacokinetics (PK), pharmacodynamics (PD), and anti-tumor activity of GEN3017 as a monotherapy in participants with relapsed or refractory (R/R) CD30-expressing lymphomas.
• DelveInsight's Non-Hodgkin Lymphoma pipeline report depicts a robust space with 200+ Non-Hodgkin Lymphoma companies working to develop 220+ pipeline therapies for Non-Hodgkin Lymphoma treatment.
• The leading Non-Hodgkin Lymphoma Companies such as Novartis, AstraZeneca, Genentech, BioInvent, Genmab, SystImmune, Nordic Nanovector, Pacylex Pharmaceuticals, Artiva Biotherapeutics, Inc., Chipscreen Biosciences, Ltd., Timmune Biotech Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Gilead Sciences, Acerta Pharma BV, Adagene Inc., Conjupro Biotherapeutics, Inc., Rhizen Pharmaceuticals, Juventas Cell Therapy Ltd., Incyte Corporation, HUYA Bioscience International, SecuraBio, Genor Biopharma Co., Ltd. Kyowa Kirin Co., Ltd., Antengene Therapeutics Limited, Regeneron Pharmaceuticals, Jiangsu HengRui Medicine Co., Ltd., Xynomic Pharmaceuticals, Inc., BioTheryX, Inc., UWELL Biopharma, Kronos Bio, Bio-Thera Solutions, Spectrum Pharmaceuticals, Inc., Aptose Biosciences Inc., Miltenyi Biomedicine GmbH, Precision BioSciences, Inc., Teneobio, Inc., TCR2 Therapeutics, IGM Biosciences, Inc., and others.
• Promising Non-Hodgkin Lymphoma Pipeline Therapies in the various stages of development include Bortezomib + Rituximab, Epcoritamab, Lenalidomide, Ibrutinib, GNC-038, ABT-199, Bendamustine, and others.

Stay informed about the cutting-edge advancements in Non-Hodgkin Lymphoma treatments. Download for updates and be a part of the revolution in care @ Non-Hodgkin Lymphoma Clinical Trials Assessment- https://www.delveinsight.com/sample-request/non-hodgkins-lymphoma-nhl-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Non-Hodgkin Lymphoma Emerging Drugs Profile

• Mosunetuzumab: Hoffmann-la Roche
Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. Mosunetuzumab simultaneously binds to CD3 epsilon (CD3e), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in a majority of B-cell malignancies. This results in crosslinking of the TCR, inducing downstream signaling events that lead to B-cell killing. Mosunetuzumab is equipped with structural features that promote T-cell recruitment and retention, resulting in an antitumor effect. In preclinical models, mosunetuzumab induced T-cell proliferation and B-cell death; furthermore, efficient B-cell killing was achieved at low effector-to-target (T cell:B cell) ratios. Use of mosunetuzumab in combination with PD-L1 inhibition may address adaptive immune resistance mechanisms to enhance anticancer activity against B-cell malignancies. The drug is being evaluated in Phase III Study to evaluate the efficacy and safety of Mosunetuzumab in combination with Polatuzumab Vedotin in comparison with rituximab in combination with gemcitabine plus oxaliplatin in participants with relapsed or refractory aggressive b-cell Non-Hodgkin's Lymphoma.

• Tisagenlecleucel: Novartis
Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy that involves genetically modified autologous T cells isolated from each individual patient. The reprogramming of the patient's T cells uses a lentiviral vector to encode an anti-CD19 chimeric antigen receptor (CAR). The CAR is comprised of a murine single-chain antibody fragment (scFv) specific for CD19, followed by a CD8 hinge and transmembrane region that is fused to the intracellular signaling domains from 4-1BB (CD137) and CD3 zeta Label. These intracellular costimulatory signaling domains increase the expansion, longer-term persistence and potency of CAR T cells: the CD3 zeta component is critical for initiating T-cell activation and antitumor activity, while 4-1BB enhances the expansion and persistence of tisagenlecleucel {FDA Label, A20379]. Upon binding to CD19-expressing cells, the CAR transmits a signal to promote T-cell expansion, activation, target cell elimination, and persistence of the tisagenlecleucel cells. Currently, it is in Phase III stage of clinical trial evaluation to treat Non-Hodgkin Lymphoma.

• Capivasertib: AstraZeneca
Capivasertib binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism. Currently, it is in Phase II stage of clinical trial evaluation to treat Non-Hodgkin Lymphoma.

• BI-1206: BioInvent
BI-1206 is a high-affinity monoclonal antibody that selectivity binds to Fc?RIIB (CD32B), the only inhibitory member of the Fc?R family. Fc?RIIB is overexpressed in several forms of NHL and overexpression has been associated with poor prognosis in difficult-to treat forms of NHL, such as mantle cell lymphoma. By blocking Fc?RIIB, BI-1206 is expected to recover and enhance the activity of rituximab or other anti-CD20 monoclonal antibodies in the treatment of these diseases. In January 2023, positive data was presented from the ongoing clinical Phase I/IIa study of BI-1206 in combination with rituximab for the treatment of non-Hodgkin's lymphoma (NHL). Data suggest that BI-1206 restores activity of rituximab in relapsed NHL patients.

• HMPL-760: Hutchmed
HMPL-760 is an investigational, highly selective, non-covalent, third-generation inhibitor of BTK, both wild-type and C481S mutant enzymes, with pre-clinical data suggesting high target specificity and higher potency versus first generation BTK inhibitors. BTK C481S mutation plays an important role in resistance to certain BTK inhibitors.

Learn more about Non-Hodgkin Lymphoma Drugs opportunities in our groundbreaking Non-Hodgkin Lymphoma Research and development projects @ Non-Hodgkin Lymphoma Unmet Needs- https://www.delveinsight.com/sample-request/non-hodgkins-lymphoma-nhl-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Non-Hodgkin Lymphoma Companies
AstraZeneca, Genentech, BioInvent, Genmab, SystImmune, Nordic Nanovector, Pacylex Pharmaceuticals, Artiva Biotherapeutics, Inc., Chipscreen Biosciences, Ltd., Timmune Biotech Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Gilead Sciences, Acerta Pharma BV, Adagene Inc., Conjupro Biotherapeutics, Inc., Rhizen Pharmaceuticals, Juventas Cell Therapy Ltd., Incyte Corporation, HUYA Bioscience International, SecuraBio, Genor Biopharma Co., Ltd. Kyowa Kirin Co., Ltd., Antengene Therapeutics Limited, Regeneron Pharmaceuticals, Jiangsu HengRui Medicine Co., Ltd., Xynomic Pharmaceuticals, Inc., BioTheryX, Inc., UWELL Biopharma, Kronos Bio, Bio-Thera Solutions, Spectrum Pharmaceuticals, Inc., Aptose Biosciences Inc., Miltenyi Biomedicine GmbH, Precision BioSciences, Inc., Teneobio, Inc., TCR2 Therapeutics, IGM Biosciences, Inc., and others.

Non-Hodgkin Lymphoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• intravenous
• Subcutaneous
• Topical.

Non-Hodgkin Lymphoma Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

Discover the latest advancements in Non-Hodgkin Lymphoma treatment by visiting our website. Stay informed about how we're transforming the future of disease @ Non-Hodgkin Lymphoma Market Drivers and Barriers, and Future Perspectives- https://www.delveinsight.com/sample-request/non-hodgkins-lymphoma-nhl-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Non-Hodgkin Lymphoma Pipeline Report
• Coverage- Global
• Non-Hodgkin Lymphoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Non-Hodgkin Lymphoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Non-Hodgkin Lymphoma Companies- Novartis, AstraZeneca, Genentech, BioInvent, Genmab, SystImmune, Nordic Nanovector, Pacylex Pharmaceuticals, Artiva Biotherapeutics, Inc., Chipscreen Biosciences, Ltd., Timmune Biotech Inc., Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Gilead Sciences, Acerta Pharma BV, Adagene Inc., Conjupro Biotherapeutics, Inc., Rhizen Pharmaceuticals, Juventas Cell Therapy Ltd., Incyte Corporation, HUYA Bioscience International, SecuraBio, Genor Biopharma Co., Ltd. Kyowa Kirin Co., Ltd., Antengene Therapeutics Limited, Regeneron Pharmaceuticals, Jiangsu HengRui Medicine Co., Ltd., Xynomic Pharmaceuticals, Inc., BioTheryX, Inc., UWELL Biopharma, Kronos Bio, Bio-Thera Solutions, Spectrum Pharmaceuticals, Inc., Aptose Biosciences Inc., Miltenyi Biomedicine GmbH, Precision BioSciences, Inc., Teneobio, Inc., TCR2 Therapeutics, IGM Biosciences, Inc., and others.
• Non-Hodgkin Lymphoma Pipeline Therapies- Bortezomib + Rituximab, Epcoritamab, Lenalidomide, Ibrutinib, GNC-038, ABT-199, Bendamustine, and others.

For a detailed overview of our latest research findings and future plans, read the full details of Non-Hodgkin Lymphoma Pipeline on our website @ Non-Hodgkin Lymphoma Emerging Drugs and Companies- https://www.delveinsight.com/sample-request/non-hodgkins-lymphoma-nhl-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Non-Hodgkin Lymphoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Non-Hodgkin Lymphoma - DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. Tisagenlecleucel: Novartis
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. Capivasertib: AstraZeneca
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I/II)
14. BI-1206: BioInvent
15. Drug profiles in the detailed report…..
16. Early Stage Products (Phase I)
17. HMPL-760: Hutchmed
18. Drug profiles in the detailed report…..
19. Preclinical Stage Products
20. Product Name: Company Name
21. Drug profiles in the detailed report…..
22. Inactive Products
23. Non-Hodgkin Lymphoma Key Companies
24. Non-Hodgkin Lymphoma Key Products
25. Non-Hodgkin Lymphoma- Unmet Needs
26. Non-Hodgkin Lymphoma- Market Drivers and Barriers
27. Non-Hodgkin Lymphoma- Future Perspectives and Conclusion
28. Non-Hodgkin Lymphoma Analyst Views
29. Non-Hodgkin Lymphoma Key Companies
30. Appendix

List of the Top Selling Market Research Reports in 2024

Celiac Disease Market: https://www.delveinsight.com/report-store/celiac-disease-cd-market
Coronary Stents Market: https://www.delveinsight.com/report-store/coronary-stents-market-market
CXCR Inhibitors Market: https://www.delveinsight.com/report-store/selective-inhibitor-of-the-cxcr4-chemokine-receptor-market-forecast
Diabetic Gastroparesis Market: https://www.delveinsight.com/report-store/gastroparesis-market
Fertility Monitoring Devices Market: https://www.delveinsight.com/report-store/fertility-monitoring-devices-fertility-testing-devices-market
Phototherapies for Psoriasis Market: https://www.delveinsight.com/report-store/phototherapies-for-psoriasis-market
Pipeline Assessment Services: https://www.delveinsight.com/consulting/pipeline-assessment-services
Ranibizumab Biosimilars Market: https://www.delveinsight.com/report-store/ranibizumab-biosimilars-insight
Rhinitis Market: https://www.delveinsight.com/report-store/rhinitis-market
Skin Grafting Devices Market: https://www.delveinsight.com/report-store/skin-grafting-devices-market
Spinal Implants Market: https://www.delveinsight.com/report-store/spinal-implants-market
Surgical Sealant Market: https://www.delveinsight.com/report-store/surgical-sealant-and-adhesives-market
Thrombectomy Devices Market: https://www.delveinsight.com/report-store/thrombectomy-devices-market
Venous Ulcer Market: https://www.delveinsight.com/report-store/venous-leg-ulcer-market
ADHD Market: https://www.delveinsight.com/report-store/attention-deficit-hyperactivity-disorder-adhd-market
Bacterial Meningitis Market: https://www.delveinsight.com/report-store/meningococcal-meningitis-market
Heart Pump Devices Market: https://www.delveinsight.com/report-store/heart-pump-device-market
Meningococcal Meningitis Market: https://www.delveinsight.com/report-store/meningococcal-meningitis-market
Percutaneous Arterial Closure Device Market: https://www.delveinsight.com/report-store/vascular-closure-devices-market
Pouchitis Market: https://www.delveinsight.com/report-store/pouchitis-market
Respiratory Syncytial Virus Market: https://www.delveinsight.com/report-store/respiratory-syncytial-virus-rsv-market
Shingles Market: https://www.delveinsight.com/report-store/shingles-market
Artificial Disc Market: https://www.delveinsight.com/report-store/artificial-disc-market
Avascular Necrosis Market: https://www.delveinsight.com/report-store/avascular-necrosis-market
Embolotherapy Market: https://www.delveinsight.com/report-store/embolotherapy-market
Orthopedic Power Devices Market: https://www.delveinsight.com/report-store/orthopedic-power-devices-market
Perennial Allergic Rhinitis Market: https://www.delveinsight.com/report-store/allergic-rhinitis-market
Plaque Psoriasis Market: https://www.delveinsight.com/report-store/plaque-psoriasis-market
Psoriasis Vulgaris Market: https://www.delveinsight.com/report-store/psoriasis-vulgaris-market
Transcatheter Heart Valve Replacement Devices Market: https://www.delveinsight.com/report-store/transcatheter-aortic-valve-replacement-market
UK Healthcare Report: https://www.delveinsight.com/report-store/uk-healthcare-outlook-report
Attention Deficit Hyperactivity Disorder Market: https://www.delveinsight.com/report-store/attention-deficit-hyperactivity-disorder-adhd-market
Brucellosis Market: https://www.delveinsight.com/report-store/brucellosis-market
Coronary Angioplasty Market: https://www.delveinsight.com/report-store/coronary-stents-market-market
NK Cell Therapy Market: https://www.delveinsight.com/report-store/nk-cell-therapy-market
Scoliosis Market: https://www.delveinsight.com/report-store/scoliosis-market
Surgical Site Infections Market: https://www.delveinsight.com/report-store/surgical-site-infections-ssi-market
Attention Deficit Hyperactivity Disorder ADHD Market: https://www.delveinsight.com/report-store/attention-deficit-hyperactivity-disorder-adhd-market
Catheter Stabilization Devices Market: https://www.delveinsight.com/report-store/catheter-stabilization-securement-device-market
Diabetic Wound Market: https://www.delveinsight.com/report-store/diabetic-foot-ulcers-dfus-market
Dyspepsia Market: https://www.delveinsight.com/report-store/functional-dyspepsia-market-share
Indwelling Catheters Market: https://www.delveinsight.com/report-store/indwelling-catheters-market
Orthopedic Splints Device Market: https://www.delveinsight.com/report-store/orthopedic-splints-market
Sepsis Market: https://www.delveinsight.com/report-store/sepsis-market
Overactive Bladder Syndrome Market: https://www.delveinsight.com/report-store/overactive-bladder-market
Spinal Trauma Devices Market: https://www.delveinsight.com/report-store/spinal-trauma-devices-market-market
Temporomandibular Disorders Market: https://www.delveinsight.com/report-store/temporomandibular-disorders-market
Viscosupplementation Devices Market: https://www.delveinsight.com/report-store/viscosupplementation-devices-market
Vitreoretinal Surgery Devices Market: https://www.delveinsight.com/report-store/vitreoretinal-surgery-devices-market
Advanced Liver Cancer Market: https://www.delveinsight.com/report-store/liver-cancer-market
Gene Therapy in CNS Disorder Market: https://www.delveinsight.com/report-store/gene-therapy-in-cns-disorder-market
Lice Infestations Market: https://www.delveinsight.com/report-store/lice-infestations-market
Plantar Fasciitis Market: https://www.delveinsight.com/report-store/plantar-fasciitis-market
Biopsy Devices Market: https://www.delveinsight.com/report-store/biopsy-devices-market
Endoscopic Ultrasound Market: https://www.delveinsight.com/report-store/endoscopic-ultrasound-market
Healthcare Consulting Solutions: https://www.delveinsight.com/consulting
Pelvic Organ Prolapse Market: https://www.delveinsight.com/report-store/pelvic-organ-prolapse-market
Pulmonary Emphysema Market: https://www.delveinsight.com/report-store/chronic-obstructive-pulmonary-disease-copd-market
Schistosomiasis Market: https://www.delveinsight.com/report-store/schistosomiasis-market
Testicular Neoplasm Market: https://www.delveinsight.com/report-store/testicular-neoplasm-market
Tourette Syndrome Market: https://www.delveinsight.com/report-store/tourette-syndrome-market
Wound Healing Devices Market: https://www.delveinsight.com/report-store/wound-healing-devices-market
Chronic Neuropathic Pain Market: https://www.delveinsight.com/report-store/chronic-neuropathic-pain-market
Fabry Disease Market: https://www.delveinsight.com/report-store/fabry-disease-market
Transcatheter Treatment Market: https://www.delveinsight.com/report-store/transcatheter-treatment-market
SGLT2 Inhibitors Market: https://www.delveinsight.com/report-store/sglt2-inhibitors-market
Surgical Lasers Market: https://www.delveinsight.com/report-store/surgical-lasers-market
Stem Cell Market: https://www.delveinsight.com/report-store/stem-cell-market
Myeloproliferative Neoplasms Market: https://www.delveinsight.com/report-store/myeloproliferative-neoplasms-market
Pacemakers Market: https://www.delveinsight.com/report-store/pacemakers-market
Urea Cycle Disorders Market: https://www.delveinsight.com/blog/urea-cycle-disorder-market
Varicose Vein Treatment Devices Market: https://www.delveinsight.com/report-store/varicose-vein-treatment-devices-market
Bone Growth Stimulator Market: https://www.delveinsight.com/report-store/bone-growth-stimulators-market
Intraocular Lens Market: https://www.delveinsight.com/blog/top-companies-in-the-intraocular-lens-market
Lymphoedema Market: https://www.delveinsight.com/report-store/lymphedema-market
Somatotropin Deficiency Market: https://www.delveinsight.com/report-store/somatotropin-deficiency-market
Skin Neoplasm Market: https://www.delveinsight.com/report-store/nonmelanoma-skin-cancer-market
Antibody Drug Conjugate Market: https://www.delveinsight.com/report-store/antibody-drug-conjugate-market
Healthcare Competitive Benchmarking: https://www.delveinsight.com/consulting/competitive-benchmarking-services
Surgical Mask & Respirator Market: https://www.delveinsight.com/report-store/surgical-mask-respirator-market
Meibomian Gland Dysfunction Market: https://www.delveinsight.com/report-store/meibomian-gland-dysfunction-pipeline-insight
Novel Drug Delivery Devices Market: https://www.delveinsight.com/report-store/novel-drug-delivery-devices
Total Knee Arthroplasty Market: https://www.delveinsight.com/report-store/total-knee-arthroplasty-market
Asperger Syndrome Market: https://www.delveinsight.com/report-store/autism-spectrum-disorder-asd-market
Medical Marijuana Market: https://www.delveinsight.com/report-store/medical-marijuana-market-insight
Lactose Intolerance Market: https://www.delveinsight.com/report-store/lactose-intolerance-market
Microscopy Device Market: https://www.delveinsight.com/sample-request/microscopy-device-market

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: info@delveinsight.com
Phone: 09650213330
Address: 304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/

This release was published on openPR.