Press release
Next-Generation Drug Conjugates Market Report: Drivers, Challenges, and Forecasts to 2031.
InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Next Generation Drug Conjugates Market- (By Type (Peptide Receptor Radionuclide Therapy, Ligand mediated RNAi Conjugate, Ligand Conjugated Anti Sense Medicine and Peptide Drug Conjugate), By Type of Targeting Ligand (Amino Sugar, Peptide, Lipid, Small Molecule and Virus-like Particles), By Type of Payload (Peptide, Small Molecule, Oligonucleotide, Radionuclide), By Type of Therapy (Monotherapy, Combination Therapy), By Route of Administration, By Target Indications, By Region, Trends, Industry Competition Analysis, Revenue and Forecast To 2031."According to the latest research by InsightAce Analytic, the Global Next Generation Drug Conjugates Market is valued at US$ 2.61 Bn in 2023, and it is expected to reach US$ 7.94 Bn by 2031, with a CAGR of 15.1% during the forecast period of 2024-2031.
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Growth of the next-generation drug conjugates market is driven by several factors, such as the recent accelerated approvals of various next-generation drug conjugates and the keen interest shown by the big pharma players in forging strategic alliances with the next-generation drug conjugate developers. The ever-growing rise in medicare costs, along with the increasing burden of rare disease indications, prompted the stakeholders to look for alternatives to conventional therapies. As a result, the next-generation conjugates combine cytotoxic drugs with targeting agents, enhancing drug efficacy while reducing systemic toxicity. Deeper cellular penetration and permeability have emerged as viable targeted therapeutics for rare disease indications, including cancers.
List of Prominent Players in the Next Generation Drug Conjugates Market:
• Advanced Accelerator Applications
• Alnylam Pharmaceuticals
• Arrowhead Pharmaceuticals
• Dicerna Pharmaceuticals
• Geron Corporation
• Ionis Pharmaceuticals
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Market Dynamics:
Drivers-
The rising prevalence of various cancers globally drives the demand for more effective and targeted treatment options like antibody drug conjugates (ADCs). ADCs offer precise targeting of cancer cells, minimizing damage to healthy tissues and decreasing side effects compared to traditional chemotherapy. Technological Advancements and Continuous innovations in drug conjugation technologies enhance the efficacy and safety profiles of ADCs, attracting investment and driving market growth. A favorable regulatory environment, along with supportive regulatory frameworks, expedites the development and approval processes for ADCs, encouraging investment and market expansion. Partnerships between pharmaceutical companies, research institutions, and biotechnology firms facilitate the development of novel ADCs and accelerate their commercialization. A robust pipeline of ADC candidates targeting different cancers fuels market growth by expanding treatment options and addressing unmet medical needs.
Challenges:
The global next-generation drug conjugates market faces several formidable challenges. One of the primary obstacles is the high development cost associated with these therapies. The complex manufacturing processes required for drug conjugates involve sophisticated technology and stringent quality control measures, making scalability difficult and expensive. Additionally, the regulatory landscape presents significant hurdles; furthermore, gaining permission from regulatory bodies like the FDA and EMA is a time-consuming and expensive process that frequently necessitates substantial clinical trials to prove safety and efficacy. Another major challenge is ensuring the stability and efficacy of drug conjugates. In order to be effective, these therapies must both release the therapeutic agent at the target site in a controlled manner and be stable under physiological conditions. Balancing these requirements while minimizing toxicity is a complex scientific and technical task. Patents and proprietary technology can restrict the capacity of new companies to enter the market and innovate, which further complicates intellectual property issues.
Regional Trends:
The North American next generation drug conjugates market is growing due to advanced healthcare infrastructure and significant R&D investments. Key players in the region are driving innovation in targeted cancer therapies, leveraging cutting-edge technologies for drug conjugation. The increasing cases of cancer and the rising demand for personalized medicine boost the market. Favorable regulatory policies further stimulate market growth, allowing swift approval and commercialization of novel drug conjugates. Moreover, strategic collaborations between pharmaceutical companies and research institutions fuel the development of next-generation therapies. With a robust pipeline and expanding applications beyond oncology, the North American market for drug conjugates is poised for sustained expansion.
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Recent Developments:
• In April 2023, Novartis entered into a licensing agreement with 3B Pharmaceuticals. 3B Pharmaceuticals is a German-based company involved in the growth of peptide receptor radionuclide therapy (PRRT) candidates targeting fibroblast activation protein (FAP) receptors.
• In March 2023, Japan-based PeptiDream signed strategic partnership with US-based RayzeBio to develop a peptide-radioisotope (RI) conjugate against Glypican-3 ("GPC3") expressed in liver cancers.
• In March 2023, The USFDA accepted Ionis Pharmaceutical's New Drug Application (NDA) for its investigational antisense medication Eplontersen, which is intended for patients with hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN). After Amvuttra (vutrisiran) from Alnylam, Eplontersen will be the second medication licensed for the treatment of hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN).
Segmentation of Next Generation Drug Conjugates Market-
Next Generation Drug Conjugates Market- By Type
• Peptide Receptor Radionuclide Therapy (Peptide Radionuclide Conjugate)
• Ligand-mediated RNAi Conjugate
• Ligand Conjugated Antisense Medicine
• Peptide Drug Conjugate
Next Generation Drug Conjugates Market- By Targeting Ligand
• Amino Sugar
• Lipid
• Peptide
• Small Molecule
• Virus-like Particles
Next Generation Drug Conjugates Market- By Payload
• Peptide
• Small Molecule
• Oligonucleotide
• Radionuclide
Next Generation Drug Conjugates Market- By Therapy
• Monotherapy
• Combination Therapy
Next Generation Drug Conjugates Market- By Route of Administration
• Intravenous
• Subcutaneous
• Others
Next Generation Drug Conjugates Market- By Indications
• Gastroenteropancreatic Neuroendocrine Tumors
• Prostate Cancer
• Leptomeningeal Carcinomatosis caused by Breast Cancer Brain Metastases
• Hereditary Transthyretin Amyloidosis
• Atherosclerotic Cardiovascular Diseases
• Severe Hypertriglyceridemia
• Hereditary Angioedema
• Acute Hepatic Porphyria
• Primary Hyperoxaluria
• Heterozygous Familial Hypercholesterolemia
• Hemophilia
• Low-Risk Myelodysplastic Syndrome
• Myelofibrosis
• Familial Chylomicronemia Syndrome
• Alpha-1 Antitrypsin Deficiency Liver Disease
Next Generation Drug Conjugates Market- By Region
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of Middle East and Africa
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About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
Contact us:
InsightAce Analytic Pvt. Ltd.
Visit: www.insightaceanalytic.com
Tel : +1 551 226 6109
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info@insightaceanalytic.com
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