Chronic Lower Back Pain Clinical Trials, Emerging Therapies, Key Companies | Pipeline Analysis Report 2024 | DelveInsight

DelveInsight's, "Chronic Lower Back Pain - Pipeline Insight, 2024," report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Chronic Lower Back Pain pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
DelveInsight's 'Chronic Lower Back Pain Pipeline Insight 2024 [https://www.delveinsight.com/report-store/chronic-lower-back-pain-pipeline-insight?utm_source=abnewswire&utm_medium=market&utm_campaign=kpr]' report provides comprehensive global coverage of available, marketed, and pipeline Chronic Lower Back Pain therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Chronic Lower Back Pain pipeline domain.

Key Takeaways from the Chronic Lower Back Pain Pipeline Report [https://www.delveinsight.com/sample-request/chronic-lower-back-pain-pipeline-insight?utm_source=abnewswire&utm_medium=market&utm_campaign=kpr]

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Over 10+ Chronic Lower Back Pain pipeline therapies are in various stages of development, and their anticipated acceptance in the Chronic Lower Back Pain market would significantly increase market revenue.

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Leading Chronic Lower Back Pain companies developing novel drug candidates to improve the Chronic Lower Back Pain treatment landscape include Mesoblast, Persica Pharmaceuticals, and others.

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Promising Chronic Lower Back Pain pipeline therapies in various stages of development include MPC-06-ID, PP353, and others.

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In July 2024, Semnur Pharmaceuticals, Inc., a subsidiary of Scilex Holding Company, and Denali Capital Acquisition Corp. (Nasdaq: DECA) signed a letter of intent for a proposed business combination. This deal values Semnur at up to USD 2.0 billion, subject to adjustments, with expected cash on hand of up to USD 40 million at closing. The merger aims to create a publicly traded biopharma company and secure funding for Semnur's development of SP-102 (SEMDEXA), a Phase III non-opioid treatment for sciatica with FDA Fast Track status.

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In February 2023, the FDA OTAT granted RMAT designation for rexlemestrocel-L in the treatment of CLBP associated with disc degeneration, in combination with HA as a delivery agent for injection into the lumbar disc.

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Early in 2021, Mesoblast published results from the Phase III trial MSBDR003 that was carried out in the US and Australia. The trial provided a number of important findings, including a significant and long-lasting treatment effect on pain relief. However, it did not achieve its primary outcome measure between the treatment groups.

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In November 2015, the FDA granted tentative approval to the NDA for XTAMPZA for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Chronic Lower Back Pain Overview

Low back pain that has been present for longer than three months is considered as chronic, although there is still no consensus about the definition of Chronic Lower Back Pain (CLBP). 5-10% of all low back pain patients will develop CLBP. Chronic low back pain (CLBP) has been associated with neurochemical, structural, and functional cortical changes of several brain regions including the somatosensory cortex. Complex processes of peripheral and central sensitization may influence the evolution of acute to chronic pain. Most patients that suffer from CLBP experience pain in the lower area of the back (lumbar and sacroiliac regions) and mobility impairment. Diagnosis of low back pain is done on the basis of physical examination and patient history, sometimes followed by x-rays, CT scan, MRI, or other medical tests. Treatment for CLBP includes medications like acetaminophen (Tylenol), ibuprofen (Advil), and naproxen (Aleve). Physical therapy, occupational therapy, and lifestyle modification as well as other forms of exercise are also helpful.

Chronic Lower Back Pain Pipeline Analysis: Drug Profile

PP353: Persica Pharmaceuticals

PP353 is a unique combination of an antibiotic, a radio-opaque dye and a thermosensitive gel that provides a product for intradiscal injection. It is currently being studied in Phase I/II developmental studies for the treatment of patients with Chronic Low Back Pain associated with verterbral body endplate bone oedema.

Discover more about the emerging Chronic Lower Back Pain drugs @ Chronic Lower Back Pain Treatment Drugs [https://www.delveinsight.com/report-store/chronic-lower-back-pain-pipeline-insight?utm_source=abnewswire&utm_medium=market&utm_campaign=kpr]

Chronic Lower Back Pain Key Companies

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Mesoblast

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Persica Pharmaceuticals

Chronic Lower Back Pain Pipeline Therapies

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MPC-06-ID

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PP353

Chronic Lower Back Pain Pipeline Therapeutics Assessment

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By development stage

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By product type

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By route of administration

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By molecule type

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By MOA type

Scope of the Chronic Lower Back Pain Pipeline Report [https://www.delveinsight.com/sample-request/chronic-lower-back-pain-pipeline-insight?utm_source=abnewswire&utm_medium=market&utm_campaign=kpr]

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Coverage: Global

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Key Chronic Lower Back Pain Companies: Mesoblast, Persica Pharmaceuticals, and others

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Key Chronic Lower Back Pain Pipeline Therapies: MPC-06-ID, PP353, and others

Find out more about the Chronic Lower Back Pain treatment options in development @ Chronic Lower Back Pain Clinical Trials [https://www.delveinsight.com/report-store/chronic-lower-back-pain-pipeline-insight?utm_source=abnewswire&utm_medium=market&utm_campaign=kpr]

Table of Contents

1. Introduction

2. Executive Summary

3. Overview

4. Pipeline Therapeutics

5. Late-Stage Products (Phase III)

6. Mid-Stage Products (Phase II)

7. Early Stage Products (Phase I/II)

8. Preclinical Stage Products

9. Discovery Stage Products

10. Therapeutic Assessment

11. Inactive Products

12. Collaborations Assessment- Licensing / Partnering / Funding

13. Unmet Needs

14. Market Drivers and Barriers

15. Appendix

16. About DelveInsight

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