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Neurotrophic Keratitis Pipeline Analysis 2024: FDA Approvals, Clinical Trials, Therapies, Mechanism of Action, Route of Administration by DelveInsight

12-06-2024 10:12 AM CET | Health & Medicine

Press release from: DelveInsight Business Research

Neurotrophic Keratitis Pipeline

Neurotrophic Keratitis Pipeline

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, Neurotrophic Keratitis pipeline constitutes 4+ key companies continuously working towards developing 4+ Neurotrophic Keratitis treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Neurotrophic Keratitis Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Neurotrophic Keratitis Market.
The Neurotrophic Keratitis Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Request for Sample Report here @ https://www.delveinsight.com/report-store/neurotrophic-keratitis-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Some of the key takeaways from the Neurotrophic Keratitis Pipeline Report:
• Neurotrophic Keratitis Companies across the globe are diligently working toward developing novel Neurotrophic Keratitis treatment therapies with a considerable amount of success over the years.
• Neurotrophic Keratitis companies working in the treatment market are ReGenTree, RegeneRx Biopharmaceuticals, Inc, Recordati Rare Diseases, Viatris, MimeTech, Claris Bio Therapeutics and others, are developing therapies for the Neurotrophic Keratitis treatment
• Emerging Neurotrophic Keratitis therapies such as OXERVATE (Cenegermin-bkbj/rhNGF), RGN-259 (Timbetasin), REC 0559 (MT-8/Udonitrectag/REC 0/0559), BRM424, OC-01 (varenicline) and others are expected to have a significant impact on the Neurotrophic Keratitis market in the coming years.
• In October 2024, BRIM Biotechnology Inc announced results of an Open-Label, Multi-Center, Phase 2 Dose Ranging Study of BRM424 Ophthalmic Solution in Patients With Neurotrophic Keratitis (NK)
• In April 2024, ReGenTree, LLC announced results of a Phase 3, Multi-Center, Randomized, Parallel, Double Masked, Placebo-Controlled Clinical Study to Assess the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of Neurotrophic Keratopathy (SEER-2)

Neurotrophic Keratitis Overview
Neurotrophic keratitis (NK) is a rare degenerative corneal disease caused by impaired corneal innervation, leading to a loss of corneal sensitivity and subsequent epithelial breakdown. This condition progresses through three stages: punctate keratopathy, persistent epithelial defects, and corneal ulcers or perforation. Without timely intervention, NK can result in severe vision loss.
Common causes of Neurotrophic keratitis include herpetic infections (herpes simplex or herpes zoster), ocular surgery, long-term contact lens use, diabetes, or systemic conditions such as multiple sclerosis. Cranial nerve damage, particularly of the trigeminal nerve, is the primary underlying factor disrupting normal corneal healing and tear production.
Symptoms of Neurotrophic keratitis are often mild or absent due to reduced corneal sensitivity, which delays diagnosis. Patients may present with redness, blurred vision, or recurrent epithelial defects. Neurotrophic keratitis Diagnosis involves clinical evaluation, slit-lamp examination, and assessment of corneal sensitivity using tools like the Cochet-Bonnet esthesiometer.
Management focuses on promoting corneal healing and preventing complications. Treatment options include artificial tears, protective bandage contact lenses, tarsorrhaphy, and regenerative therapies such as nerve growth factor (cenegermin). Surgical interventions like amniotic membrane transplantation or corneal grafts may be required for advanced stages.
Early diagnosis and a multidisciplinary approach are crucial to preserving vision and improving outcomes for patients with Neurotrophic keratitis.

Get a Free Sample PDF Report to know more about Neurotrophic Keratitis Pipeline Therapeutic Assessment- https://www.delveinsight.com/sample-request/neurotrophic-keratitis-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Neurotrophic Keratitis Route of Administration
Neurotrophic Keratitis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Neurotrophic Keratitis Molecule Type
Neurotrophic Keratitis Products have been categorized under various Molecule types, such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Neurotrophic Keratitis Pipeline Therapeutics Assessment
• Neurotrophic Keratitis Assessment by Product Type
• Neurotrophic Keratitis By Stage and Product Type
• Neurotrophic Keratitis Assessment by Route of Administration
• Neurotrophic Keratitis By Stage and Route of Administration
• Neurotrophic Keratitis Assessment by Molecule Type
• Neurotrophic Keratitis by Stage and Molecule Type

DelveInsight's Neurotrophic Keratitis Report covers around 4+ products under different phases of clinical development like-
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Neurotrophic Keratitis product details are provided in the report. Download the Neurotrophic Keratitis pipeline report to learn more about the emerging Neurotrophic Keratitis therapies- https://www.delveinsight.com/report-store/neurotrophic-keratitis-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Neurotrophic Keratitis Pipeline Analysis:
The Neurotrophic Keratitis pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Neurotrophic Keratitis with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Neurotrophic Keratitis Treatment.
• Neurotrophic Keratitis key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Neurotrophic Keratitis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Neurotrophic Keratitis market.

Download Sample PDF Report to know more about Neurotrophic Keratitis drugs and therapies- https://www.delveinsight.com/sample-request/neurotrophic-keratitis-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Scope of Neurotrophic Keratitis Pipeline Drug Insight
• Coverage: Global
• Key Neurotrophic Keratitis Companies: ReGenTree, RegeneRx Biopharmaceuticals, Inc, Recordati Rare Diseases, MimeTech, Claris Bio Therapeutics and others.
• Key Neurotrophic Keratitis Therapies: OXERVATE (Cenegermin-bkbj/rhNGF), RGN-259 (Timbetasin), REC 0559 (MT-8/Udonitrectag/REC 0/0559), BRM424, OC-01 (varenicline) and others.
• Neurotrophic Keratitis Therapeutic Assessment: Neurotrophic Keratitis current marketed and Neurotrophic Keratitis emerging therapies
• Neurotrophic Keratitis Market Dynamics: Neurotrophic Keratitis market drivers and Neurotrophic Keratitis market barriers

Request for Sample PDF Report for Neurotrophic Keratitis Pipeline Assessment and clinical trials - https://www.delveinsight.com/sample-request/neurotrophic-keratitis-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Table of Contents
1. Neurotrophic Keratitis Report Introduction
2. Neurotrophic Keratitis Executive Summary
3. Neurotrophic Keratitis Overview:
4. Neurotrophic Keratitis- Analytical Perspective In-depth Commercial Assessment
5. Neurotrophic Keratitis Pipeline Therapeutics
6. Neurotrophic Keratitis Late Stage Products (Phase II/III)
7. Neurotrophic Keratitis Mid Stage Products (Phase II)
8. Neurotrophic Keratitis Early Stage Products (Phase I)
9. Neurotrophic Keratitis Preclinical Stage Products
10. Neurotrophic Keratitis Therapeutics Assessment
11. Neurotrophic Keratitis Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Neurotrophic Keratitis Companies
14. Neurotrophic Keratitis Key Products
15. Neurotrophic Keratitis Unmet Needs
16 . Neurotrophic Keratitis Market Drivers and Barriers
17. Neurotrophic Keratitis Future Perspectives and Conclusion
18. Neurotrophic Keratitis Analyst Views
19. Appendix
20. About DelveInsight

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