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ProBio offers AAV One-stop Solution for AAV vector

12-02-2024 01:38 PM CET | Health & Medicine

Press release from: Getnews

/ PR Agency: Website Servicer Co.,Ltd

AAV One-stop Solution

Process development for triple transfection

Support regulatory filing

AAV vector is widely used delivery vehicle due to its high safety and effectiveness in delivering Gene of Interest (GOI). ProBio is broadening its business in AAV services [https://www.probiocdmo.com/gct-one-stop-aav.html]to cater to the market demand.

Image: https://www.probiocdmo.com/img/probio/gct-one-stop-aav-banner.jpg

One-stop Solution for AAV

ProBio offers services from cell banking, process development, AAV packaging [https://www.probiocdmo.com/gct-one-stop-aav.html], analytical development, to GMP manufacturing and stability test for AAV vector. ProBio is also ready to prepare reports and documents to support the regulatory filings.

ProBio is also able to produce AAV plasmids [https://www.probiocdmo.com/gct-plasmid-overview.html] to take care of your projects from plasmids to AAV.

Packaging Test

* To evaluate the titer and function of AAV

Demo Run

* Small scale production evaluation

Cell Banking

* MCB/WCB Construction
* Cell Bank Characterization
* Cell Bank Stability Test

Process Development (PD)

* Upstream Process Development
* Downstream Process Development
* Formulation Process Development

Verification Run

* Verification run
* QC and release

Engineering Run

* Full scale in clean room, used for toxicology batch
* QC and release

Analytical Development

* Analytical Method Development
* Analytical Method Qualification

GMP Manufacturing

* GMP Manufacturing
* Quality Control and Release

Stability Test

* Accelerated Stability Test
* Influencing Factor Stability Test
* Long-term Stability Test

Regulatory Support

* Report and document preparation for regulatory filing

Production of AAV

Among the various ways of producing AAV vector, the most mature, versatile and cost-effective one is triple transient transfection system. Three plasmids, helper plasmid, Rep/Cap plasmid and AAV transfer plasmid, are co-transfected in packaging cell line, such as HEK 293, to manufacture AAV.

Image: https://www.probiocdmo.com/img/gsprobio/gct-one-stop-aav-production.jpg

Advantages of AAV One-stop Solutions [https://www.probiocdmo.com/gct-one-stop-aav.html]

Professional

Professional team averagely over 10 years of virus production experience

Efficiency

Process development for specific project based on platform experience

Cutting-edge technology

ddPCR for titer measurementAUC for full ratio measurement

Guarantee Delivery

Strict product release criteriaDocument preparation for regulatory filing
Media Contact
Company Name: ProBio CDMO
Email: Send Email [http://www.universalpressrelease.com/?pr=probio-offers-aav-onestop-solution-for-aav-vector]
Phone: 1-877-436-7274 (Toll-Free)
Country: United States
Website: https://www.probiocdmo.com



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