Press release
Diabetic Neuropathic Pain Clinical Trials | A Drug Pipeline Analysis Report 2024 | AstraZeneca, Centrexion Therapeutics, Aptinyx
Diabetic Neuropathic Pain Pipeline Analysis Report 2024
Download our free sample pages: https://www.delveinsight.com/report-store/diabetic-neuropathic-pain-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Key Takeaways from the Diabetic Neuropathic Pain Pipeline Report
Leading Diabetic Neuropathic Pain companies developing novel drug candidates to improve the Diabetic Neuropathic Pain treatment landscape include AstraZeneca, Centrexion Therapeutics, Aptinyx, and others.
Promising Diabetic Neuropathic Pain pipeline therapies in various stages of development include MEDI 7352, CNTX6016, NYX2925, and others.
Diabetic Neuropathic Pain Overview
Diabetic neuropathic pain is a type of nerve pain that occurs as a complication of diabetes mellitus. It arises due to damage to the nerves caused by prolonged exposure to high blood sugar levels (hyperglycemia). This condition can significantly impact the quality of life of individuals with diabetes, affecting daily activities and overall well-being.
Diabetic Neuropathic Pain Causes:
The primary cause of diabetic neuropathic pain is nerve damage due to diabetes. High blood sugar levels over time can lead to:
1. Axonal degeneration: Damage to nerve fibers that transmit sensory information.
2. Microvascular complications: Reduced blood flow to nerves, impairing their function and leading to nerve ischemia.
3. Inflammation: Chronic inflammation associated with diabetes contributes to nerve damage.
Diabetic Neuropathic Pain Signs and Symptoms:
Diabetic neuropathic pain can manifest in various ways, depending on the type and location of nerve damage. Common signs and symptoms include:
1. Painful sensations:
- Burning: A persistent burning sensation, often described as hot or scalding.
- Tingling: Electric-like tingling or pins and needles sensation.
- Shooting or stabbing pain: Sudden, sharp pains that may occur intermittently.
2. Increased sensitivity:
- Hyperalgesia: Heightened sensitivity to pain stimuli, where normally non-painful stimuli become painful.
- Allodynia: Painful response to stimuli that are not typically painful, such as light touch or clothing brushing against the skin.
3. Numbness or reduced sensation:
- Gradual loss of sensation, particularly in the feet and hands, leading to difficulty detecting temperature or pressure changes.
4. Muscle weakness or atrophy:
- Due to nerve damage affecting motor function, leading to difficulty with fine motor tasks or muscle wasting.
5. Autonomic symptoms:
- Changes in sweating patterns (excessive sweating or lack of sweating), blood pressure fluctuations, or gastrointestinal symptoms.
Diabetic Neuropathic Pain Diagnosis:
Diagnosing diabetic neuropathic pain involves a thorough evaluation by a healthcare provider, including:
1. Medical History and Physical Examination:
- Assessment of symptoms, duration, and progression of neuropathic pain.
- Neurological examination to evaluate sensory, motor, and autonomic function.
2. Nerve Function Tests:
- Nerve conduction studies (NCS): Measures the speed and strength of electrical signals transmitted through nerves.
- Electromyography (EMG): Measures electrical activity in muscles to assess nerve-muscle function.
3. Quantitative Sensory Testing (QST):
- Evaluates sensory thresholds to detect abnormalities in sensory perception.
4. Blood Tests:
- HbA1c: Measures average blood sugar levels over the past 2-3 months to assess diabetes control.
- Comprehensive metabolic panel to assess kidney function, liver function, and electrolyte levels.
Diabetic Neuropathic Pain Treatment Options:
Treatment for diabetic neuropathic pain focuses on managing symptoms, improving quality of life, and preventing complications:
1. Medications:
- Antidepressants: Tricyclic antidepressants (e.g., amitriptyline) or selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) such as duloxetine can help relieve neuropathic pain.
- Anticonvulsants: Medications like gabapentin or pregabalin are effective for neuropathic pain management.
- Topical agents: Capsaicin cream or lidocaine patches may provide localized pain relief.
2. Pain Management Techniques:
- Transcutaneous electrical nerve stimulation (TENS): Uses electrical currents to relieve pain.
- Acupuncture: Some individuals find relief from neuropathic pain with acupuncture treatments.
- Cognitive-behavioral therapy (CBT): Helps individuals cope with pain and improve psychological well-being.
3. Blood Sugar Control:
- Optimal glycemic control through diet, exercise, and medications (insulin or oral antidiabetic agents) to prevent further nerve damage.
4. Physical Therapy:
- Exercises to improve strength, flexibility, and balance.
- Techniques to improve gait and prevent falls.
5. Foot Care:
- Regular foot examinations to detect changes in sensation or skin integrity.
- Proper foot hygiene and moisturizing to prevent dry skin and cracking.
- Wearing appropriate footwear to reduce the risk of foot ulcers.
6. Multidisciplinary Approach:
- Collaboration with healthcare providers including neurologists, pain specialists, physical therapists, and dietitians for comprehensive management.
Diabetic Neuropathic Pain Outlook:
The prognosis for diabetic neuropathic pain depends on early diagnosis, effective management of diabetes, and prompt intervention to alleviate symptoms. While diabetic neuropathic pain can be challenging to treat, a combination of therapies tailored to individual needs can often provide significant relief and improve overall quality of life. Close monitoring and ongoing management are essential to prevent progression and complications associated with neuropathic pain.
Diabetic Neuropathic Pain Pipeline Analysis: Drug Profile
MEDI 7352- AstraZeneca
MEDI 7352 is an NGF/TNF bispecific mAb. Bispecific antibodies are artificial proteins. They are composed of two monoclonal antibodies held together by a flexible peptide linker. As the name suggests, this helps them bind to two different antigens. It involves investigating the effect of MEDI7352 on chronic pain in patients with painful diabetic neuropathy.
It is currently in a Phase II clinical trial to study the efficacy and safety of MEDI7352 in subjects with Painful Diabetic Neuropathy.
Discover more about the emerging Diabetic Neuropathic Pain drugs @ https://www.delveinsight.com/sample-request/diabetic-neuropathic-pain-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Diabetic Neuropathic Pain Key Companies
AstraZeneca
Centrexion Therapeutics
Aptinyx
Diabetic Neuropathic Pain Pipeline Therapies
MEDI 7352
CNTX6016
NYX2925
Diabetic Neuropathic Pain Pipeline Therapeutics Assessment
By development stage
By product type
By route of administration
By molecule type
By MOA type
Scope of the Diabetic Neuropathic Pain Pipeline Report
Coverage: Global
Key Diabetic Neuropathic Pain Companies: AstraZeneca, Centrexion Therapeutics, Aptinyx, and others
Key Diabetic Neuropathic Pain Pipeline Therapies: MEDI 7352, CNTX6016, NYX2925, and others
Find out more about the Diabetic Neuropathic Pain treatment options in development @ https://www.delveinsight.com/sample-request/diabetic-neuropathic-pain-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Table of Contents
1. Introduction
2. Executive Summary
3. Overview
4. Pipeline Therapeutics
5. Late-Stage Products (Phase III)
6. Mid-Stage Products (Phase II)
7. Early Stage Products (Phase I/II)
8. Preclinical Stage Products
9. Discovery Stage Products
10. Therapeutic Assessment
11. Inactive Products
12. Collaborations Assessment- Licensing / Partnering / Funding
13. Unmet Needs
14. Market Drivers and Barriers
15. Appendix
16. About DelveInsight
Trending Reports By DelveInsight:
Functional Constipation Market
https://www.delveinsight.com/report-store/chronic-constipation-market
Lebers Hereditary Optic Neuropathy Lhon Market https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market
Gastric Neuroendocrine Tumors Market
https://www.delveinsight.com/report-store/gastric-neuroendocrine-tumors-market
Immune Thrombocytopenic Purpura Market
https://www.delveinsight.com/report-store/immune-thrombocytopenia-itp-market
Visceral Pain Associated With GI Disorders Market
https://www.delveinsight.com/report-store/visceral-pain-associated-with-gi-disorders-market
Bullous Pemphigoid Market
https://www.delveinsight.com/report-store/bullous-pemphigoid-market
Cyclin-dependent Kinase-like 5 Deficiency Disorder Market https://www.delveinsight.com/infographics/cyclin-dependent-kinase-like-5-cdkl5-deficiency-disorder-market
Myocarditis Market
https://www.delveinsight.com/report-store/myocarditis-market
Recurrent Blood Clots Market
https://www.delveinsight.com/report-store/recurrent-blood-clots-thrombophilia-market
Zollinger-ellison Syndrome Market
https://www.delveinsight.com/report-store/zollinger-ellison-syndrome-market
Age-related Hearing Loss Medical Device Market
https://www.delveinsight.com/blog/age-related-hearing-loss-device-market
Heart Sounds Sensors Market
https://www.delveinsight.com/report-store/heart-sounds-sensors-electronic-stethoscope-market
Hypoplastic Left Heart Syndrome Hlhs Market
https://www.delveinsight.com/report-store/hypoplastic-left-heart-syndrome-market
Infectious Arthritis/Septic Arthritis Market
https://www.delveinsight.com/report-store/infectious-arthritisseptic-arthritis-market
Plasmacytoma Market
https://www.delveinsight.com/report-store/plasmacytoma-market
Agoraphobia Market
https://www.delveinsight.com/report-store/agoraphobia-market
Clinically Isolated Syndrome CIS Market
https://www.delveinsight.com/report-store/clinically-isolated-syndrome-cis-market
Fucosidosis Market
https://www.delveinsight.com/report-store/fucosidosis-market
Major Depressive Disorder Market
https://www.delveinsight.com/report-store/major-depressive-disorder-market
Neuronal Ceroid-lipofuscinoses Market
https://www.delveinsight.com/report-store/neuronal-ceroid-lipofuscinoses-cln1-disease-market
Orthotic Devices Market
https://www.delveinsight.com/report-store/orthotic-devices-market
Contact Us
Kritika Rehani
info@delveinsight.com
+14699457679
About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences.
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Diabetic Neuropathic Pain Clinical Trials | A Drug Pipeline Analysis Report 2024 | AstraZeneca, Centrexion Therapeutics, Aptinyx here
News-ID: 3757916 • Views: …
More Releases from DelveInsight Business Research LLP
Genital Warts Pipeline Insights Report 2025 | DelveInsight
DelveInsight's, "Genital Warts Pipeline Insight 2025" report provides comprehensive insights about 30+ companies and 30+ pipeline drugs in Genital Warts pipeline landscape. It covers the Genital Warts pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore the comprehensive insights by DelveInsight and stay ahead…
Traumatic Brain Injury Pipeline Drugs Report 2025 | DelveInsight
DelveInsight's "Traumatic Brain Injury Pipeline Insight 2025" report provides comprehensive insights about 20+ companies and 22+ pipeline drugs in Tthe raumatic Brain Injury pipeline landscape. It covers the Traumatic Brain Injury pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Traumatic Brain Injury pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore…
Bone Metastasis Pipeline Assessment Report 2025 | DelveInsight
DelveInsight's, "Bone Metastases Pipeline Insight, 2025," report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Bone Metastases pipeline landscape. It covers the Bone Metastasis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Bone Metastasis pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore the comprehensive insights by DelveInsight…
Acquired Immunodeficiency Syndrome Treatment Market Size Report 2032 | DelveInsi …
DelveInsight's "Acquired Immunodeficiency Syndrome Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Acquired Immunodeficiency Syndrome, historical and forecasted epidemiology as well as the Acquired Immunodeficiency Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
To Know in detail about the Acquired Immunodeficiency Syndrome market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Acquired Immunodeficiency Syndrome Market…
More Releases for Pain
Enhanced Pain Relief Solutions at Advanced Pain Care
Image: https://www.globalnewslines.com/uploads/2025/03/3f3b6259bfdec02e5dcb7b9d0c838855.jpg
Advanced Pain Care is helping people who suffer from chronic pain with sophisticated, evidence-based treatments. The clinic is particularly focused on non-surgical care that improves the quality of life. With a team of highly qualified pain experts, they work with patients who have back pain, joint pain, and nerve pain.
Personalized Treatment for Every Pain Disorder
Advanced Pain Care offers treatments depending on the cause of pain. Anyone experiencing arthritis, migraine,…
Pain Finisher | Advanced Pain Relief Device
Pain Finisher is an instant pain relief device that is effective on all pains including back pain and knee pain. It is based on the TENS theory of pain management which is easy to use and safe.
By using Pain Finisher, a modern drug-free and non-invasive pain-relieving treatment method, one can get rid of the common pain creams, gels, and risky treatment methods.
So, have a pain-free life with easy-to-use pain relief…
Neuropathic Pain Market: Innovative Therapies Reshaping Chronic Pain Management
In recent years, the global Neuropathic Pain Market has witnessed a dynamic shift, influenced by changing consumer preferences, technological advancements, and a growing emphasis on sustainability. The Research report on Neuropathic Pain Market presents a complete judgment of the market through strategic insights on future trends, growth factors, supplier landscape, demand landscape, Y-o-Y growth rate, CAGR, pricing analysis. It also provides and a lot of business matrices including…
Visceral Pain Market Analysis 2024: Addressing Pain Management Challenges
The Business Research Company has released its latest global market reports, covering insights for 2024 and offering projections up to 2033.
The Business Research Company presents an extensive market research report on the Visceral Pain Global Market Report 2024, furnishing businesses with a competitive edge through a detailed examination of the market structure, encompassing estimates for various segments and sub-segments.
Furthermore, the report highlights on emerging trends, significant drivers, challenges, and opportunities,…
Global Post-Operative Pain Management Market: Pain Relief Goes Worldwide
Introduction:
The Global Post-Operative Pain Management Market is growing at a rapid pace. This market involves the management of pain after surgical procedures. The market has witnessed significant growth in recent years, owing to the increasing number of surgeries and the rising prevalence of chronic diseases. Pain management is an essential aspect of healthcare, as uncontrolled pain can lead to prolonged hospital stays, delayed recovery, and poor patient outcomes.
In this article,…
Post-Operative Pain Management Market By Type, By Application(Cancer Pain, Arthr …
Global Post-Operative Pain Management Market- Description
Post-operative pain management is predominantly referred to as the use of a wide array of therapies or drugs to reduce muscle and tissue spasm in patients who have recently undergone a surgical procedure. It is evident that all type of surgeries, be it major or minor cause postoperative pain in patients which in turn increases their hospital stays while burdening them with psychological and physical…
