Molecular Cytogenetics Technologies Such FISH And Acgh Are Providing New Dimensions To The Areas Of Research And Molecular Diagnostics

Molecular cytogenetics refers to the study of chromosomal structures with use of molecular techniques. The technique provides a combination of both molecular and cytological approach to research and diagnosis. Molecular cytogenetics is being considered as an indispensable tool for the diagnosis and research of numerous chromosomal aberrations. The technique is preferred over traditional chromosomal banding technique as traditional techniques provide low resolution level and may escape detection of copy number variations.

The breakthrough in the molecular cytogenetics technologies such FISH and aCGH are providing new dimensions to the areas of research and molecular diagnostics. These techniques are considered as invaluable tool for gene mapping, gene discovery and complex disease trait analysis. Molecular cytogenetics facilitates diagnosis and prognosis of diseases associated with hematological malignancies and solid tumors at molecular level. Likewise, alongwith diagnosis and prognosis of tumors, the technique is facilitating the practice of personalized medicines. The global molecular cytogenetics market was valued at USD 469.2 million in 2012 and is expected to grow at a CAGR of 23.4% from 2013 to 2019 to reach at an estimated value of USD 1.9 billion in 2019.

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As stated in the report, the rising occurrence of cancer globally and the introduction of advanced and modern technologies for molecular cytogenesis have propelled the growth of the market. On the other hand, the absence of transparency and widespread availability of medical reimbursement policies may impede the growth of the market in the coming years.

On the basis of technology, the report segments the market for molecular cytogenetics into array-comparative genomic hybridization (aCGH) and fluorescence in situ hybridization (FISH). Amongst these, the aCGH technique has gained more demand than the FISH technique due to its high-resolution results and accurate analysis as compared to other conventional banding techniques. This segment is predicted to rise at a CAGR of over 20% from 2013 to 2019 and is poised to dominate the market on the basis of demand.

On the other hand, the segment of FISH also holds a dominant share in the market; the technology has been utilized since the past many years for identifying numerous diseases and for suggesting suitable treatment options. In addition, this technique is also backed by the ongoing advancements within the field of bioinformatics and genomics. FISH has emerged as a key tool for disease validation and thus is increasingly utilized in hospitals and laboratories. By application, the report segments the market into cancer, genetic disorders, personalized medicines, and others including infectious, cardiovascular, and neurological diseases.

By geography, the report segments the molecular cytogenetics market into Asia Pacific, North America, Europe, and Rest of the World (RoW). Amongst these, the North America molecular cytogenetics market held the largest share in 2012 and was trailed by Europe. The growth of the market in these two regions is fuelled by factors such as the increasing awareness amongst people about molecular cytogenetics and the growing count of research laboratories within these regions. In addition, the advancement of personalized medicines and the increasing occurrence of cancer in these two regions will also augment the growth of the market here. On the other hand, Asia Pacific is predicted to emerge as the most swiftly developing market in the forecast horizon due to the increasing population base within this region.

According to the report, the prime players operating in the market for molecular cytogenetics are Abbott Laboratories, Agilent Technologies, Inc., Oxford Gene Technology, Illumina, Inc., and Bio-Rad Laboratories, among others.

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