Infliximab Biosimilar Insights Report 2023 by DelveInsight | Celltrion, Pfizer, Merck, Biocad, and others

DelveInsight's "Infliximab Biosimilar Insight, 2023" report provides comprehensive insights about 35+ companies and 45+ marketed and pipeline drugs in Infliximab Biosimilars landscape. It covers the marketed and pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Geography Covered: Global coverage

Infliximab Overview

Infliximab belongs to the class of medications known as tumor necrosis factor (TNF) inhibitors and is utilized in the treatment of various autoimmune disorders, particularly those characterized by chronic inflammation. Its mode of action involves targeting and neutralizing tumor necrosis factor-alpha (TNF-α), a cytokine pivotal in the inflammatory process. By impeding TNF-α activity, Infliximab mitigates inflammation and alleviates symptoms associated with specific autoimmune conditions.

Clinical use of Infliximab extends to conditions such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriatic arthritis, ankylosing spondylitis, and psoriasis, where excessive TNF-α exacerbates inflammation. Administration typically involves intravenous infusion, often conducted in a healthcare facility, with infusion frequency adjusted based on the particular ailment.

Its mechanism of action hinges on TNF-α, a pro-inflammatory cytokine crucial in immune responses. By binding to TNF-α, Infliximab curbs its activity, resulting in diminished inflammation. This modus operandi aids in symptom control, tissue damage prevention, and disease progression slowdown in autoimmune disorders.

In clinical settings, Infliximab has demonstrated efficacy in symptom management, enhanced quality of life, and disease progression attenuation across various autoimmune maladies. Nonetheless, it does not represent a curative treatment and necessitates vigilant monitoring and oversight by healthcare providers due to potential adverse effects.

Common side effects associated with Infliximab encompass heightened susceptibility to infections, infusion reactions, and, albeit rare, severe adverse events. Patients receiving Infliximab are routinely subjected to close monitoring for any indications of adverse reactions.

Prior to initiating Infliximab therapy, healthcare practitioners assess the patient's medical history, including the presence of infections, and may conduct screening assessments. Patients are advised to communicate any ongoing infections or other medical conditions to their healthcare provider before commencing treatment.
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Infliximab Biosimilars: Marketed Drugs
1. Inflectra: Celltrion/Pfizer
2. Renflexis: Merck
Infliximab Biosimilars: Emerging Drugs
1. BCD 055: Biocad
2. CT-P17: Celltrion
Major Players in Infliximab

There are approximately 20+ Infliximab biosimilars key companies such as Celltrion, Pfizer, Merck, Biocad, and others which are developing the therapies for Infliximab.
To understand key companies related to the Infliximab Biosimilars Market, get a snapshot @ https://www.delveinsight.com/report-store/infliximab-biosimilars-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr

Infliximab Biosimilars Report Highlights:
1. The companies and academics are working to assess challenges and seek opportunities that could influence Infliximab R&D. The therapies under development are focused on novel approaches to treat/improve Infliximab.
2. In July 2017, Merck had launched in the U.S. a biosimilar of Remicade (infliximab), the blockbuster immune-mediated inflammatory disorders treatment it markets outside the U.S., including Europe, while partner Janssen Biotech markets the drug stateside.
3. In December 2017, Pfizer announced that the United States (U.S.) Food and Drug Administration (FDA) has approved IXIFI (PF-06438179, infliximab-qbtx), a chimeric human-murine monoclonal antibody (mAb) against tumor necrosis factor, as a biosimilar to Remicade (infliximab) for all eligible indications of the reference product. The FDA has approved IXIFI as a treatment for patients with rheumatoid arthritis, Crohn's disease, pediatric Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis.

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Table of Contents:

1. Key Insights
2. Infliximab Biosimilars: Snapshot
3. Executive Summary
4. Regulatory Outlook For Biosimilars
5. Infliximab (Reference Product: Remicade)
6. Research and Development
7. Remicade Biosimilar: Emerging Opportunities
8. Infliximab: Biosimilars Assessment
9. Infliximab Biosimilars Profiles: By Company
10. Infliximab Biosimilars: Comparative Landscape: By Company
11. Infliximab Biosimilars: Competitive Landscape
12. Market Drivers
13. Market Barriers
14. SWOT Analysis
15. Appendix
16. Bibliography
17. DelveInsight Capabilities
18. Disclaimer
19. About DelveInsight

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