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Synovial Sarcoma Pipeline Therapeutics, Assessment, Companies, Products, Unmet Needs, Market Drivers and Barriers

11-11-2024 02:09 PM CET | Health & Medicine

Press release from: DelveInsight Business Research LLP

Synovial Sarcoma Pipeline

Synovial Sarcoma Pipeline

DelveInsight's, "Synovial Sarcoma Pipeline Insight 2024" report provides comprehensive insights about 15+ companies and 20+ pipeline drugs in Synovial-Sarcoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Explore our latest breakthroughs in Synovial Sarcoma Research. Learn more about our innovative pipeline today! @ Synovial Sarcoma Pipeline Outlook- https://www.delveinsight.com/sample-request/synovial-sarcoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the Synovial Sarcoma Pipeline Report
• In October 2024:- University Health Network, Toronto- The purpose of this study is to evaluate the safety profile of TBI-1301, to determine the recommended phase 2 (RP2D) dose of TBI-1301 when administered following cyclophosphamide and fludarabine pre-treatment, to evaluate the safety of repeat dosing of TBI-1301, to assess the presence/absence of RCR appearance after TBI-1301 infusion, to assess the presence or absence of clonality by LAM-PCR, and to evaluate evidence of efficacy of TBI-1301 using RECIST v1.1.
• In October 2024:- Daiichi Sankyo- This is a global, multicenter, open-label, first-in-human, Phase 1 trial of DS-2243a as a treatment for locally advanced or metastatic synovial sarcoma (SS), myxoid/round cell liposarcoma (MRCLS), squamous cell carcinoma type non-small cell lung cancer (Sq-NSCLC), adenocarcinoma type non-small cell lung cancer (Ad-NSCLC), or urothelial carcinoma (UC) participants with HLA-A2 and/or NY-ESO positive. The trial consists of 2 parts: the Dose Escalation Part (Part 1) and the Dose Expansion Part (Part 2).
• DelveInsight's Synovial Sarcoma pipeline report depicts a robust space with 15+ active players working to develop 20+ pipeline therapies for Synovial Sarcoma treatment.
• The leading Synovial Sarcoma Companies such as Advenchen Laboratories, Ipsen, OncoTherapy Science, C4 Therapeutics, Takara Bio, BioAtla, Inc., Immatics Biotechnologies GmbH, Sapience Therapeutics, PharmaMar, and others
• Promising Synovial Sarcoma Therapies such as AL3818, Dacarbazine, Doxorubicin, APX005M, Cyclophosphamide, TBI-1301, Fludarabine, and others.

Stay informed about the cutting-edge advancements in Synovial Sarcoma treatments. Download for updates and be a part of the revolution in care @ Synovial Sarcoma Clinical Trials Assessment- https://www.delveinsight.com/sample-request/synovial-sarcoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Synovial Sarcoma Emerging Drugs Profile
• AL3818: Advenchen Laboratories
Anlotinib (AL3818) is a novel oral receptor tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor 2 and 3, fibroblast growth factor 1-4, platelet-derived growth factor receptor α and β, c-Kit and Ret. Anlotinib exerts inhibitory effects on tumor growth and angiogenesis. Anlotinib has encouraging efficacy and a manageable and tolerable safety profile in a broad range of malignancies, including medullary thyroid cancer, renal cell cancer, gastric cancer and esophageal squamous cell carcinoma. Currently, the drug is in the Phase III stage of its development for the treatment of Synovial sarcoma.
• Tazemetostat: Ipsen
Tazemetostat is a first-in-class, oral small molecule inhibitor of the epigenetic enzyme EZH2. It is one of the histone methyltransferases in the epigenetics-related protein group, and is thought to regulate the expression of cancer-related genes and suppress the growth of cancer cells by specifically targeting EZH2, which contributes to the cancer growth process. Eisai holds the rights for development and commercialization of tazemetostat in Japan, where it was approved for the indication of "relapsed or refractory EZH2 gene mutation-positive follicular lymphoma (only when standard treatment is not applicable)" in 2021, and manufactures and distributes the product. Currently, the drug is being evaluated in the Phase II stage of its development for the treatment of synovial sarcoma.
• OTSA101: OncoTherapy Science
OTSA101 is an anti-FZD10 antibody and has been developed as novel cancer therapy for synovial sarcoma. FZD10, which was identified through genome-wide analysis by the group of Professor Yusuke Nakamura (former Director of Human genome center, Institute of Medical Science,The University of Tokyo ) is frequently and highly up regulated in synovial sarcoma but being hardly detectable in normal organs. OTSA101 specifically binds to FZD10 in cancer cells. In addition, radioactive isotope-conjugated OTSA101 showed strong anti-cancer activity by tumor-specific irradiation in mouse xenograft model. Currently, the drug is in the Phase I stage of its development for the treatment of synovial sarcoma.

Learn more about Synovial Sarcoma Drugs opportunities in our groundbreaking Synovial Sarcoma Research and development projects @ Synovial Sarcoma Unmet Needs- https://www.delveinsight.com/sample-request/synovial-sarcoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Synovial Sarcoma Companies
Advenchen Laboratories, Ipsen, OncoTherapy Science, C4 Therapeutics, Takara Bio, BioAtla, Inc., Immatics Biotechnologies GmbH, Sapience Therapeutics, PharmaMar, and others.

Synovial-Sarcoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Synovial Sarcoma Products have been categorized under various Molecule types such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Discover the latest advancements in Synovial Sarcoma treatment by visiting our website. Stay informed about how we're transforming the future of disease @ Synovial Sarcoma Market Drivers and Barriers, and Future Perspectives- https://www.delveinsight.com/sample-request/synovial-sarcoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Synovial Sarcoma Pipeline Report
• Coverage- Global
• Synovial Sarcoma Companies- Advenchen Laboratories, Ipsen, OncoTherapy Science, C4 Therapeutics, Takara Bio, BioAtla, Inc., Immatics Biotechnologies GmbH, Sapience Therapeutics, PharmaMar, and others
• Synovial Sarcoma Therapies- AL3818, Dacarbazine, Doxorubicin, APX005M, Cyclophosphamide, TBI-1301, Fludarabine, and others.
• Synovial Sarcoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Synovial Sarcoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

For a detailed overview of our latest research findings and future plans, read the full details of Synovial Sarcoma Pipeline on our website @ Synovial Sarcoma Emerging Drugs and Companies- https://www.delveinsight.com/sample-request/synovial-sarcoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Synovial Sarcoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Synovial Sarcoma- DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. AL3818: Advenchen Laboratories
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. Tazemetostat: Ipsen
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. OTSA101: OncoTherapy Science
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug Name: Company Name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Synovial Sarcoma Key Companies
21. Synovial Sarcoma Key Products
22. Synovial Sarcoma- Unmet Needs
23. Synovial Sarcoma- Market Drivers and Barriers
24. Synovial Sarcoma- Future Perspectives and Conclusion
25. Synovial Sarcoma Analyst Views
26. Synovial Sarcoma Key Companies
27. Appendix

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About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

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