Pulmonary Hypertension associated with Interstitial Lung Disease Market Size in the 7MM was ~USD 1,400 million in 2023, estimated DelveInsight

DelveInsight's "Pulmonary Hypertension associated with Interstitial Lung Disease Market Insights, Epidemiology, and Market Forecast - 2034" report delivers an in-depth understanding of Pulmonary Hypertension associated with Interstitial Lung Disease, historical and forecasted epidemiology, as well as the Pulmonary Hypertension associated with Interstitial Lung Disease market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

The Pulmonary Hypertension associated with Interstitial Lung Disease Market is an evolving segment of the global healthcare landscape, driven by the increasing prevalence of the disorder and the continuous development of innovative treatment options. The Pulmonary Hypertension associated with Interstitial Lung Disease market encompasses various therapeutic categories, including antipsychotics, adjunctive therapies, and emerging treatment modalities.

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Key Takeaways from the Pulmonary Hypertension associated with Interstitial Lung Disease Market Report

* In October 2024:- Pulmovant Inc.- A Phase 2, Randomized, Placebo-Controlled Trial to Assess the Efficacy and Safety of Mosliciguat in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease. This is a Phase 2, randomized, double-blind, placebo-controlled, multi-center clinical study to evaluate the safety and efficacy of inhaled mosliciguat in participants with pulmonary hypertension associated with interstitial lung disease (PH-ILD).
* In October 2024:- Liquidia Technologies Inc.- This Phase 3, 2-part, open-label, multicenter study aims to demonstrate the safety and tolerability of L606 in patients with PAH or PH-ILD. The study will determine the short-term and long-term safety and tolerability of L606 in this patient population; also evaluate the steady-state pharmacokinetics (PK) of L606 as compared to Tyvaso, effects on exercise ability, quality of life, and treatment satisfaction with L606.
* In October 2024:- Bayer- The purpose of this study is to assess multiple ascending doses of a new drug (BAY63-2521) given orally, to evaluate if it is safe and can help to improve the well-being, symptoms (e.g. disturbed breathing) and outcome of pulmonary hypertension associated with lung fibrosis. Patients living with pulmonary hypertension associated with interstitial lung disease have a risk of increased number of hospitalisations because of worsening of their condition. Until now there is no approved medication for this disease.
* In 2023, the total diagnosed prevalent cases of PH-ILD were nearly 172 thousand in the 7MM, which are expected to rise by 2034.
* Among 7MM, the United States had the highest diagnosed prevalent cases of PH-ILD with 92 thousand cases in 2023.
* EU4 and the UK countries accounted for 58 thousand diagnosed prevalent cases of PH-ILD in 2023, and is projected to increase by 2034. In 2023, with 14 thousand cases, Germany accounted for the highest number of diagnosed prevalent cases of PH-ILD, followed by the UK (13 thousand cases). On the other hand, Spain had the lowest and equal number of diagnosed prevalent population as approximately 9 thousand cases in 2023.
* The leading Pulmonary Hypertension associated with Interstitial Lung Disease Companies such as United Therapeutics Corp, Insmed Incorporated, Bellerophon Therapeutics, and others.
* Promising Pulmonary Hypertension associated with Interstitial Lung Disease Therapies such as Treprostinil Palmitil Inhalation Powder, Riociguat (Adempas, BAY63-2521), Mosliciguat, Mirivadelgat , and others.

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Pulmonary Hypertension associated with Interstitial Lung Disease Epidemiology Segmentation in the 7MM

* Pulmonary Hypertension associated with Interstitial Lung Disease Diagnosed prevalent cases
* Pulmonary Hypertension associated with Interstitial Lung Disease Type-specific Diagnosed Prevalent Cases
* Pulmonary Hypertension associated with Interstitial Lung Disease Type-specific Diagnosed Prevalent Cases
* Pulmonary Hypertension associated with Interstitial Lung Disease Diagnosed Prevalent Cases

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Pulmonary Hypertension associated with Interstitial Lung Disease Marketed Drugs

* TYVASO/TYVASO DPI (treprostinil): United Therapeutics Corp.

TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are both prostacyclin mimetics indicated for the treatment of PH-ILD [WHO Group 3]. TYVASO or TYVASO DPI can improve the ability to exercise. In December 2020, the FDA and in March 2024, the EMA granted ODD for treprostinil to treat IPF. Currently, the drug is in its late developmental phases for IPF.

Pulmonary Hypertension associated with Interstitial Lung Disease Emerging Drugs

* Treprostinil Palmitil: Insmed Incorporated

Treprostinil palmitil is a long-acting pulmonary vasodilator prodrug of treprostinil (TRE). It offers a differentiated product profile for pulmonary hypertension associated with interstitial lung disease (PH-ILD) and pulmonary arterial hypertension (PAH).

* INOpulse: Bellerophon Therapeutics

INOpulse drug-device combination therapy under the developmental pipeline of Bellerophon Therapeutics for the treatment of patients with PH-ILD. The device is designed to be portable for ambulatory patients daily inside or outside their homes. INOpulse delivery system is programmed to adjust automatically based on breathing patterns and delivers a constant and appropriate dose independent of the patient's activity.

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Pulmonary Hypertension associated with Interstitial Lung Disease Market Outlook

There is no standard approach to assessing patients' risk of PH. Currently, two formulations of inhaled treprostinil have obtained approval from the US FDA in April 2023 and May 2024 for TYVASO (inhalation solution) and TYVASO DPI (inhalation powder), respectively. The underlying lung disease is optimally treated with supplemental long-term oxygen therapy, diuretics, anticoagulants, and pulmonary rehabilitation. PH-specific therapy like prostanoids (FLOLAN, treprostinil, iloprost), endothelin receptor antagonists (bosentan, ambrisentan), and phosphodiesterase inhibitors (sildenafil) are used off-label to manage blood pressure.

Pulmonary Hypertension associated with Interstitial Lung Disease Market Insights

The appearance of increased pulmonary pressures is uniformly a harbinger of poor outcomes, and so is the case in PH-ILD. Advances in therapeutic options have led to an urgency to look for PH in ILD patients. In the usual care of ILD patients, specific symptoms, physical exam results, and laboratory and imaging findings can point to additional testing, such asechocardiography. However, further studies are needed to overcome several unmet needs on the therapeutic and diagnostic front

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Scope of the Pulmonary Hypertension associated with Interstitial Lung Disease Market Report

* Coverage- 7MM
* Pulmonary Hypertension associated with Interstitial Lung Disease Companies- United Therapeutics Corp, Insmed Incorporated, Bellerophon Therapeutics, and others.
* Pulmonary Hypertension associated with Interstitial Lung Disease Therapies- Treprostinil Palmitil Inhalation Powder, Riociguat (Adempas, BAY63-2521), Mosliciguat, Mirivadelgat, and others.
* Pulmonary Hypertension associated with Interstitial Lung Disease Competitive Intelligence Analysis: SWOT analysis and Market entry strategies
* Pulmonary Hypertension associated with Interstitial Lung Disease Unmet Needs, KOL's views, Analyst's views, Pulmonary Hypertension associated with Interstitial Lung Disease Market Access and Reimbursement

Table of Content

1: Key Insights

2: Report Introduction

3: Pulmonary Hypertension Associated with Interstitial Lung Disease Market Overview at a Glance

4: Epidemiology and Market Methodology

5: Executive Summary

6: Key Events

7: Disease Background and Overview

8: Epidemiology and Patient Population of PH-ILD

9: Patient Journey

10: Marketed drugs

11: Emerging Drugs

12. Key Cross Competition

13: Unmet Needs

14: SWOT Analysis

15: Key Opinion Leaders' Views

16: Reimbursement and Market Access

17: Appendix

18: DelveInsight Capabilities

19: Disclaimer

20: About DelveInsight

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