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CXCR4 Antagonists Market Report 2024: Market Size, Trends, and Analysis
C-X-C Chemokine Receptor 4 (CXCR4) Antagonists Global Market Report 2024
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According to The Business Research Company's, The C-X-C chemokine receptor 4 (CXCR4) antagonist market size has grown strongly in recent years. It will grow from $1.49 billion in 2023 to $1.62 billion in 2024 at a compound annual growth rate (CAGR) of 9.3%. The growth in the historic period can be attributed to increasing transparency in clinical trial data, patient-centric healthcare policies, rising prevalence of chemotherapy resistance, policies emphasizing patient-centered care and access, and increasing preference for targeted therapies.
The C-X-C chemokine receptor 4 (CXCR4) antagonist market size is expected to see strong growth in the next few years. It will grow to $2.33 billion in 2028 at a compound annual growth rate (CAGR) of 9.4%. The growth in the forecast period can be attributed to expanding applications in HIV or AIDS, rising demand for stem cell mobilization, potential in autoimmune diseases, growth in biobanking initiatives, and integration of artificial intelligence (AI) in drug discovery. Major trends in the forecast period include increasing focus on orphan drug development, development of combination therapies, adoption of precision oncology approaches, expanding clinical trials for novel therapies, and advancements in drug delivery technologies.
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Market Drivers and Trends:
The increase in the prevalence of human immunodeficiency virus (HIV) is expected to propel the growth of the spasmodic dysphonia treatment market going forward. Human immunodeficiency virus (HIV) is a virus that targets and weakens the immune system by attacking CD4 (T) cells, potentially leading to AIDS if left untreated. HIV prevalence is rising due to low awareness, limited healthcare access, higher transmission rates, and inadequate prevention in some areas. CXCR4 antagonists block the CXCR4 receptor, stopping HIV from accessing and infecting immune cells, which aids in controlling the virus and enhancing the immune response. For instance, according to Joint United Nations Programme on HIV/AIDS (UNAIDS), in 2022, there were 39 million [33.1 million-45.7 million] HIV-positive people worldwide, with 1.3 million [1 million-1.7 million] people newly infected with HIV in 2022. Therefore, the increase in the prevalence of human immunodeficiency virus (HIV) is driving the growth of the CXCR4 antagonist market.
Major companies operating in the CXCR4 antagonist market are focusing on developing bioequivalents to enhance treatment options and improve patient outcomes in various diseases. Bioequivalent refers to pharmaceutical products with similar bioavailability when compared under similar conditions. For instance, in May 2024, Gland Pharma, an India-based generic injectable manufacturing company, received approval from the United States Food and Drug Administration (US FDA) for Plerixafor Injection. The approved product is bioequivalent and therapeutically equivalent to the reference listed drug (RLD), MOZOBIL (plerixafor) injection of Genzyme Corporation. Plerixafor is a CXCR4 antagonist that, when used with granulocyte-colony stimulating factor, helps to mobilize hematopoietic stem cells into the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.
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Major Key Players of the Market:
Pfizer Inc., F-Hoffmann La Roche Ltd., Sanofi, Bristol-Myers Squibb Company, AstraZeneca plc, GlaxoSmithKline, Eli Lilly and Company, Amgen Inc., Takeda Chemical Industries Ltd., Kyowa Kirin Co. Ltd., BioLegend Inc., Kura Oncology Inc., CUSABIO TECHNOLOGY LLC, Cayman Chemical, X4 Pharmaceuticals Inc., BioLineRx Ltd., Spexis Ltd., Biokine Therapeutics Ltd., GlycoMimetics, AnorMED Inc., CohBar Inc.
C-X-C Chemokine Receptor 4 (CXCR4) Antagonists Market 2024 Key Insights:
• The C-X-C chemokine receptor 4 (CXCR4) antagonist market size is expected to see strong growth in the next few years. It will grow to $2.33 billion in 2028 at a compound annual growth rate (CAGR) of 9.4%.
• Increase In The Prevalence Of HIV Is Propelling The Growth Of CXCR4 Antagonists Market
• Advancements In Bioequivalent Enhancing CXCR4 Antagonists
• North America was the largest region in the C-X-C chemokine receptor type 4 antagonists market in 2023
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