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Adeno-Associated Viral Vectors Market Research, Outlook, Overview And Forecast To 2033
Adeno-Associated Viral Vectors Market Research
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According to The Business Research Company's, The adeno-associated viral vectors market size has grown rapidly in recent years. It will grow from $2.29 billion in 2023 to $2.69 billion in 2024 at a compound annual growth rate (CAGR) of 17.6%. The growth in the historic period can be attributed to vaccine development, increased funding and investment, academic and industrial collaborations, expansion of clinical trials, and public awareness and advocacy.
The adeno-associated viral vectors market size is expected to see rapid growth in the next few years. It will grow to $5.17 billion in 2028 at a compound annual growth rate (CAGR) of 17.7%. The growth in the forecast period can be attributed to expanding therapeutic applications, increasing the prevalence of genetic disorders, and neurological disorders, regulatory approvals and support, and cost reductions in production. Major trends in the forecast period include gene therapy advancements, technological innovations, scalable manufacturing processes, collaborations and investments, and technological advancements.
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Market Drivers and Trends:
The increasing prevalence of genetic disorders is expected to propel the growth of the adeno-associated viral vectors market going forward. Genetic disorders are conditions caused by abnormalities in an individual's DNA, leading to physical or developmental abnormalities. The improved diagnostic techniques, greater awareness, and higher reproductive age, along with environmental factors and genetic drift are leading to the rise in the prevalence of genetic disorders. Adeno-associated viral vectors are utilized in gene therapy for genetic disorders, delivering corrective genes into target cells to potentially treat conditions like muscular dystrophy or cystic fibrosis. For instance, in February 2023, according to the World Health Organization (WHO), a Switzerland-based specialized agency of the United Nations responsible for international public health, congenital diseases caused an estimated 240,000 baby deaths globally within 28 days of birth each year. An additional 170,000 children between the ages of 1 month and 5 years die as a result of congenital diseases. Therefore, the increasing prevalence of genetic disorders is driving the adeno-associated viral vectors market.
Major companies operating in the adeno-associated viral vectors market are focusing on offering off-the-shelf availability of replication-capsid plasmid to gain a competitive edge in the market. Rep/Cap plasmids, commonly utilized in gene therapy for adeno-associated virus (AAV) vector production, are readily available from numerous commercial suppliers catering to molecular biology research needs. For instance, in January 2024, Charles River Laboratories International Inc., a US-based pharmaceutical company, introduced off-the-shelf replication-capsid plasmid range streamlines AAV-based gene therapy initiatives. This expansion of their product portfolio complements existing lentiviral packaging and AAV Helper plasmid offerings, cutting manufacturing efforts by as much as 66%. These ready-to-use plasmids undergo batch production with meticulous documentation, adhering to CMC guidelines and accompanied by Certification of Analysis (COA) to facilitate IND and Clinical Trial Application (CTA) submissions.
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Major Key Players of the Market:
Pfizer Inc., Astellas Pharma, Biogen Inc., Charles River Laboratories International Inc., BioMarin Pharmaceutical Inc., Sarepta Therapeutics Inc., PTC Therapeutics, Ultragenyx Pharmaceutical, Amicus Therapeutics Inc., Oxford Biomedica, Asklepios BioPharmaceutical Inc., uniQure biopharma B.V., Spark Therapeutics Inc., Akouos inc., Adverum Biotechnologies Inc., Passage Bio Inc., AVROBIO Inc, MeiraGTx Holdings plc, GenSight Biologics S.A., Freeline Therapeutics, Aspa Therapeutics Inc., Adrenas Therapeutics Inc., 4D Molecular Therapeutics, Abeona Therapeutics Inc., Neurophth Therapeutics
Adeno-Associated Viral Vectors Market 2024 Key Insights:
• The adeno-associated viral vectors market size is expected to see rapid growth in the next few years. It will grow to $5.17 billion in 2028 at a compound annual growth rate (CAGR) of 17.7%.
• Rising Prevalence Of Genetic Disorders Fuels Growth In The Adeno-Associated Viral Vectors Market
• Advancements In Off-the-Shelf Rep/Cap Plasmids
• North America was the largest region in the adeno-associated viral vectors market in 2023
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