Vaccine Adjuvant Market To Reach USD 1.75 Billion By 2032, Says Emergen Research

The global vaccine adjuvant market is poised for significant expansion, with a projected Compound Annual Growth Rate (CAGR) of 7.0% during the forecast period. This growth is driven by the increasing prevalence of infectious diseases and the rising collaborations among market players focused on developing innovative adjuvant vaccines. The commitment to immunization programs further supports this upward trend.

Market Drivers

The demand for vaccine adjuvants is intensifying due to the rise of infectious diseases affecting cattle, including mastitis, foot-and-mouth disease, and bovine viral diarrhea. These conditions cause considerable economic losses in the livestock sector. To tackle these challenges, researchers are developing vaccines that utilize adjuvants to boost immune responses. Adjuvants, such as toll-like receptor agonists and oil emulsions, are critical in enhancing vaccine efficacy, addressing the urgent need for effective preventive measures against infectious diseases.

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Moreover, collaborations between pharmaceutical companies, research institutions, and governments are becoming more common. These partnerships pool resources and expertise, expediting the research and development of adjuvant vaccines. By working together, stakeholders can streamline vaccine development, resulting in more cost-effective and accessible adjuvant vaccines. This collaborative approach also enhances global readiness for emerging infectious diseases.

Market Restraints

Despite the promising growth prospects, the vaccine adjuvant market faces challenges related to the safety and side effects of certain adjuvants. For instance, aluminum adjuvants, commonly used in vaccines, can lead to local reactions such as pain and inflammation, and raise concerns over allergic responses. Such adverse effects, particularly in pediatric vaccines, can hinder community acceptance. Thus, developing adjuvants that improve immune responses without compromising safety is essential for broader adoption.

Emerging Trends

A notable trend in the vaccine adjuvant market is the rise of synthetic adjuvants. These newly developed adjuvants aim to overcome the limitations associated with traditional adjuvants like alum. Advances in medicinal chemistry have enabled researchers to create synthetic adjuvants with enhanced structures and immunogenic properties. This innovation allows for tailored immune responses, making it possible to design next-generation subunit vaccines with improved efficacy and safety.

Market Segmentation Insights

The global vaccine adjuvant market is segmented based on application, route of administration, and type.

Application: The research segment dominated the market in 2022, driven by its essential role in advancing vaccine technology. In-depth research ensures the effectiveness and safety of vaccines and enables the development of novel adjuvants. The commercial segment is expected to grow moderately as preventive healthcare initiatives increasingly rely on vaccines to protect populations from infectious diseases.

Route of Administration: The intramuscular segment is anticipated to hold a substantial market share due to its ability to provide sustained release of vaccines, ensuring effective immune responses. In contrast, the oral segment is expected to witness the fastest growth, thanks to its cost-effectiveness compared to injectable vaccines.

Type: The veterinary vaccine adjuvants segment is projected to generate the largest revenue share, primarily due to the increasing prevalence of zoonotic diseases that affect both animals and humans. As the demand for effective vaccines rises, veterinary adjuvants are crucial in enhancing vaccine efficacy. Conversely, the human vaccine adjuvants segment is expected to grow rapidly as advancements in vaccine technology continue to improve immune responses.

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Vaccine Adjuvant Top Companies and Competitive Landscape

The global vaccine adjuvant market is moderately fragmented, with many large and medium-sized players accounting for majority of market revenue. Major businesses are using a variety of tactics, making mergers and acquisitions, strategic agreements, and contracts, as well as creating, experimenting with, and introducing more efficient vaccine adjuvant solutions in the market.

Some major players included in the global vaccine adjuvant market report are:

Adjuvatis
GlaxoSmithKline PLC
Croda International PLC
Merck KGaA
TjKaiwei
OZ Biosciences
Brenntag Biosector
MVP Laboratories
Zhuoyue
Aphios
Novavax Inc.
MVP Technologies
Avanti Polar Lipids, Inc.
Invivogen
SEPPIC, Inc.
Spectrum Pharmaceuticals, Inc.
Agenus, Inc.
Brenntag Biosector A/S
CSL Corporate
GSK plc
Vaxart

Vaccine Adjuvant Latest Industry Updates

On May 23, 2023, Croda Pharma partnered with Botanical Solution Inc. (BSI) to accelerate the production of vaccine adjuvant QS-21, a vital component in adjuvant systems used in various vaccines, including those for RSV, malaria, and shingles. QS-21 is also employed in new vaccines and immunotherapy treatments, such as cancer. The collaboration aims to produce QS-21 sustainably from quillaja Saponaria plant cell culture, offering an eco-friendly alternative to harvesting mature trees. This partnership helps to address the limited sources of QS-21, allowing for production of next-generation adjuvant systems for new vaccine development. The move aligns with Croda's strategy to empower biologics delivery.

On January 17, 2023, Elicio Therapeutics developed lymph node-targeted adjuvants and vaccines for various aggressive cancers and infectious diseases. The company has entered into a definitive merger agreement with Angion Biomedica Corp to focus on advancing Elicio's proprietary lymph node-targeting Amphiphile (AMP) technology to develop immunotherapies, with a particular emphasis on ELI-002, a therapeutic cancer vaccine targeting mKRAS-driven tumors.

Vaccine Adjuvant Market Segmentation Analysis
For the purpose of this report, Emergen Research has segmented the global vaccine adjuvant market on the basis of type, application, deployment, enterprise size, component, vertical, and region:

Product Outlook (Revenue, USD Billion; 2019-2032)

Mineral Salt-based Adjuvant
Tensoactive Adjuvants
Adjuvant Emulsions
Liposome Adjuvants
Carbohydrate Adjuvants
Bacteria-derived Adjuvants
Virus-like Particles (VLP)
Other Product Types

Route of Administration Outlook (Revenue, USD Billion; 2019-2032)

Product Intramuscular
Subcutaneous
Oral
Intradermal
Intranasal

Usage Outlook (Revenue, USD Billion; 2019-2032)

Active Immunostimulants
Carriers
Vehicle Adjuvants

Disease Outlook (Revenue, USD Billion; 2019-2032)

Esophagus Infectious Diseases
Cancer
Others

Application Outlook (Revenue, USD Billion; 2019-2032)

Research Application
Commercial Application
Type Outlook (Revenue, USD Billion; 2019-2032)

Human Vaccine Adjuvants
Veterinary Vaccine Adjuvants

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Regional Outlook (Revenue, USD Billion; 2019-2032)

North America
U.S.
Canada
Mexico
Europe
Germany
France
UK
Italy
Spain
Benelux
Rest of Europe
Asia Pacific
China
India
Japan
South Korea
Rest of APAC
Latin America
Brazil
Rest of LATAM
Middle East & Africa
Saudi Arabia
UAE
South Africa
Turkey
Rest of Middle East & Africa

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