Nasal Polyposis Market Size is Set for Rapid Growth as Innovative Treatments and Rising Awareness Drive Demand by 2034

The Nasal Polyposis market size is expected to increase during the forecast period with the increasing prevalence, disease awareness, and promising emerging treatment options by leading companies such as Allakos Inc., Idorsia Pharmaceuticals Ltd., Optinose US Inc., GlaxoSmithKline, Novartis Pharmaceuticals, Sanofi, Pari Pharma GmbH, GlaxoSmithKline, Organon and Co, AstraZeneca, Keymed Biosciences Co.Ltd, Hoffmann-La Roche, Sanofi, Upstream Bio Inc., Eli Lilly and Company, Keymed Biosciences Co.Ltd, AnaptysBio, Inc.

[Nevada, United States] - DelveInsight's "Nasal Polyposis Market Insights, Epidemiology, and Market Forecast 2034." report offers a detailed examination of Nasal Polyposis, covering historical and predicted epidemiology, market trends, and treatment scenarios in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

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Key Findings from the Nasal Polyposis Market Report:
• The Nasal Polyposis market size is poised for significant growth, with an anticipated Compound Annual Growth Rate (CAGR) during the study period (2020-2034).
• In October, 2024: Insmed Incorporated announced that the purpose of their study is to evaluate the efficacy of brensocatib at 10 and 40 milligrams (mg) once daily (QD) compared with placebo in improving clinical symptoms of CRSsNP.
• In October, 2024: Sanofi announces that a parallel, Phase 2, 2-arm, multicenter, randomized, double-blind, placebo-controlled, proof-of-concept study for treatment of CRSwNP. The purpose of this study is to assess the efficacy, safety, and tolerability of add-on therapy with subcutaneous lunsekimig in adult participants (aged 18 to 70 years, inclusive) with CRSwNP who are inadequately controlled on intranasal corticosteroid treatment.
• In September, 2024: Genrix (Shanghai) Biopharmaceutical Co., Ltd. announced a multi-center, randomized, double blind, placebo-controlled study to evaluate the efficacy, safety, PK, PD and immumogenicity of GR1802 injection in comparison to placebo in addition to a background treatment of mometasone furcate nasal spray (MFNS) in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). Patients will receive GR1802 injection or Placebo every 2 Weeks.
• In August, 2024: Organon and Co announced that a study was conducted to evaluate the effectiveness of mometasone nasal spray in preventing polyp relapse/symptom worsening in patients after surgical treatment of nasal polyps. Patients who met Screening eligibility underwent endoscopic sino-nasal surgery (FESS) on visit 2.
• In August, 2024: GlaxoSmithKline announced that a astudy will evaluate the efficacy and safety of depemokimab (GSK3511294) in participants with Chronic rhinosinusitis with nasal polyps (CRSwNP).
• The total prevalent cases of CRS in the 7MM were found to be 69,550,461 cases in 2021, which are expected to increase at a CAGR of 0.44% during the study period (2019─2032).
• The total diagnosed prevalent cases of CRS in the 7MM were found to be 17,973,714 in 2021, which are expected to increase at a CAGR of 0.48% for the study period of 2019-2032.
• As per DelveInsight's estimates, the 7MM accounted for 4,358,603 diagnosed prevalent cases of NP in 2021, which are expected to increase during the study period (2019─2032). As per our analysis, 25% of the total diagnosed prevalent cases of CRS develop NP in the US.
• Key Nasal Polyposis Companies are as follows: Allakos Inc., Idorsia Pharmaceuticals Ltd., Optinose US Inc., GlaxoSmithKline, Novartis Pharmaceuticals, Sanofi, Pari Pharma GmbH, GlaxoSmithKline, Organon and Co, AstraZeneca, Keymed Biosciences Co.Ltd, Hoffmann-La Roche, Sanofi, Upstream Bio Inc., Eli Lilly and Company, Keymed Biosciences Co.Ltd, AnaptysBio, Inc.
• Key Nasal Polyposis Therapies are as follow: Benralizumab, AK001, Fluticasone Propionate, ACT-774312, OPN-375, Mepolizumab, Fevipiprant, Dupilumab, Budesonide, GSK3511294, Mometasone, Tezepelumab, CM310, Omalizumab, Dupilumab SAR231893, lunsekimig, Verekitug, LY3650150, CM326, Etokimab
• Launching multiple stage Nasal Polyposis pipeline products is expected to revolutionize market dynamics, further propelling market growth.

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Nasal Polyposis Overview:
Nasal polyposis (NP) is small, benign (noncancerous) drop-like growths appearing in the mucosa (lining tissues) of the nose and may block the nasal passageway. These polyps tend to be present on both sides of the nasal cavity. Small nasal polyps may not reflect any symptoms, but the larger growths or groups of nasal polyps block the nasal passages or lead to breathing problems, a lost sense of smell, and frequent infections. One-sided nasal polyps may need to be investigated further as they might be malignant nasal or sinus tumors.

Nasal Polyposis Epidemiology Segmentation:
The Nasal Polyposis market report proffers epidemiological analysis for the study period 2020-2034 in the 7MM segmented into:
• Nasal Polyposis Prevalent Cases
• Nasal Polyposis Diagnosed Prevalent Cases
• Nasal Polyposis Gender-specific Prevalence

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Nasal Polyposis Market Insights
• The introduction of biologic therapies has significantly shifted the treatment paradigm for nasal polyposis. Traditional therapies, such as corticosteroids and surgery, have limitations due to recurrence and side effects. Biologics, such as dupilumab and mepolizumab, target specific inflammatory pathways involved in nasal polyps, offering more effective and longer-lasting relief.
• The global prevalence of chronic rhinosinusitis, particularly in patients with nasal polyps, is on the rise. This increase is fueled by factors such as environmental pollution, allergens, smoking, and increasing awareness of the condition.
• Heightened awareness and improved diagnostic capabilities are contributing to earlier and more accurate diagnoses of nasal polyposis.

Nasal Polyposis Drugs Uptake
• Intranasal corticosteroids (INCS), such as fluticasone and budesonide, remain a mainstay for managing nasal polyposis, particularly in mild-to-moderate cases. Despite their widespread use, uptake is somewhat limited by side effects such as nosebleeds and dryness.
• Dupilumab (Dupixent): A monoclonal antibody targeting the IL-4 and IL-13 pathways, dupilumab has shown impressive efficacy in reducing polyp size, improving nasal congestion, and restoring the sense of smell.
• An anti-IL-5 biologic, mepolizumab is used primarily in patients with nasal polyposis associated with eosinophilic asthma. Its ability to target eosinophilic inflammation makes it particularly effective in reducing polyp burden and improving patient outcomes.
• An anti-IgE monoclonal antibody, omalizumab has shown promise in clinical trials for nasal polyposis. Though currently used primarily for asthma, its efficacy in reducing nasal polyps in allergic patients suggests potential for expanded use in this market.

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Nasal Polyposis Therapies and Key Companies:
• Benralizumab: AstraZeneca
• AK001: Allakos Inc.
• Fluticasone Propionate: Optinose US Inc.
• ACT-774312: Idorsia Pharmaceuticals Ltd.
• OPN-375: Optinose US Inc.
• Mepolizumab: GlaxoSmithKline
• Fevipiprant: Novartis Pharmaceuticals
• Dupilumab: Sanofi
• Budesonide: Pari Pharma GmbH
• GSK3511294: GlaxoSmithKline
• Mometasone: Organon and Co
• Tezepelumab: AstraZeneca
• CM310: Keymed Biosciences Co.Ltd
• Omalizumab: Hoffmann-La Roche
• Dupilumab SAR231893, lunsekimig: Sanofi
• Verekitug: Upstream Bio Inc.
• LY3650150: Eli Lilly and Company
• CM326: Keymed Biosciences Co.Ltd
• Etokimab: AnaptysBio, Inc.

Nasal Polyposis Epidemiology:
The epidemiology section provides insights into historical, current, and forecasted trends in the seven major countries (7MM) from 2020 to 2034. It explores various studies and opinions to recognize the causes of current and forecasted trends. The segmentation includes total prevalence, severity-based prevalence, gender-specific prevalence, and diagnosed cases of episodic and chronic Nasal Polyposis.

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Nasal Polyposis Market Drivers:
• Increasing Adoption of Biologics
• High Prevalence of Chronic Rhinosinusitis
• Expansion of Indications for Biologic Therapies

Nasal Polyposis Market Barriers:
• Limited Awareness in Certain Regions
• Side Effects and Risks of Corticosteroids
• Recurrence After Surgical Treatment
• Insurance and Reimbursement Challenges

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Scope of the Nasal Polyposis Market Report:
• Study Period: 2020-2034
• Coverage: 7MM (The United States, EU5, and Japan)
• Key Nasal Polyposis Companies: Allakos Inc., Idorsia Pharmaceuticals Ltd., Optinose US Inc., GlaxoSmithKline, Novartis Pharmaceuticals, Sanofi, Pari Pharma GmbH, GlaxoSmithKline, Organon and Co, AstraZeneca, Keymed Biosciences Co.Ltd, Hoffmann-La Roche, Sanofi, Upstream Bio Inc., Eli Lilly and Company, Keymed Biosciences Co.Ltd, AnaptysBio, Inc.
• Key Nasal Polyposis Therapies: Benralizumab, AK001, Fluticasone Propionate, ACT-774312, OPN-375, Mepolizumab, Fevipiprant, Dupilumab, Budesonide, GSK3511294, Mometasone, Tezepelumab, CM310, Omalizumab, Dupilumab SAR231893, lunsekimig, Verekitug, LY3650150, CM326, Etokimab
• Nasal Polyposis Therapeutic Assessment: Current marketed and emerging therapies
• Nasal Polyposis Market Dynamics: Nasal Polyposis Market drivers and Nasal Polyposis barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Nasal Polyposis Unmet Needs: Insights into unmet needs, KOL's views, Analyst's views, Market Access, and Reimbursement.

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Table of Content:

1 Key Insights
2 Report Introduction
3 Nasal Polyposis (NP) Market Overview at a Glance
4 Nasal Polyposis Market: Future Perspective
5 Executive Summary of Nasal Polyposis
6 Key Events
7 Disease Background and Overview: Nasal Polyposis
8 Epidemiology and Patient Population
9 Patient Journey
10 Marketed Therapies
11 Emerging Drugs
12 Nasal Polyposis (NP): Seven Major Market Analysis
13 KOL Views
14 SWOT Analysis
15 Unmet Needs
16 Reimbursement and Market Access
17 Appendix
20 DelveInsight Capabilities
21 Disclaimer
22 About DelveInsight

About DelveInsight:
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