Convulsive Seizures Market Size is Set for Rapid Growth as Innovative Treatments and Rising Awareness Drive Demand by 2032

The Convulsive Seizures market size is expected to increase during the forecast period with the increasing prevalence, disease awareness, and promising emerging treatment options by leading companies such as UCB Pharma, PTC Therapeutics, Shire, Takeda, Marinus Pharmaceuticals, Epygenix

[Nevada, United States] - DelveInsight's "Convulsive Seizures Market Insights, Epidemiology, and Market Forecast 2032." report offers a detailed examination of Convulsive Seizures, covering historical and predicted epidemiology, market trends, and treatment scenarios in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

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Key Findings from the Convulsive Seizures Market Report:
The Convulsive Seizures market size is poised for significant growth, with an anticipated Compound Annual Growth Rate (CAGR) during the study period (2019-2032).
In September, 2024: Marinus Pharmaceuticals announced that their study will evaluate the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).
In August, 2024: Epygenix announced that the purpose of their study was to evaluate the safety and efficacy of EPX-100 as adjunctive therapy in participants with Dravet syndrome.
In June 2023, Epygenix announced a study of phase 2 clinical trials for EPX-100 (Clemizole HCl). The aim of this research is to assess the safety and effectiveness of EPX-100 when used as an additional treatment for individuals, both children and adults, who are diagnosed with Dravet Syndrome.
In July 2023, PTC Therapeutics announced a study of phase 1 & 2 clinical trials for Vatiquinone. This study employs a parallel-arm, double-blind, placebo-controlled design. It begins with a screening phase, which involves a 28-day run-in period to establish the baseline frequency of seizures. Following this, there is a 24-week randomized phase, also placebo-controlled. Upon concluding this randomized phase, participants have the option to proceed to a 48-week long-term extension phase. During this extension period, they will be provided with open-label treatment using vatiquinone.
Around 50 million people globally are affected by epilepsy, with convulsive seizures being the most common type experienced by about 60% of these patients.
The annual incidence rate of convulsive seizures is estimated to be around 20-70 per 100,000 people in high-income countries, while this number tends to be higher in low- and middle-income regions due to factors like infections, head trauma, and poor access to healthcare.
Convulsive seizures are more prevalent among children and the elderly. Men are slightly more likely to experience seizures than women, but gender differences are minimal.
Key Convulsive Seizures Companies are as follows: UCB Pharma, PTC Therapeutics, Shire, Takeda, Marinus Pharmaceuticals, Epygenix
Key Convulsive Seizures Therapies are as follow: Ketamine, Midazolam, Levetiracetam, IV Ganaxolone active Phenobarbital, SHP615, MHOS/SHP615, EPX-100 (clemizole HCl)
Launching multiple stage Convulsive Seizures pipeline products is expected to revolutionize market dynamics, further propelling market growth.

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Convulsive Seizures Treatment Market Overview:
The Convulsive Seizures Treatment Market is a dynamic and evolving sector within the healthcare industry, dedicated to addressing the medical needs of individuals who suffer from convulsive seizures, also known as epileptic seizures. These seizures, characterized by uncontrollable and often violent muscle contractions, can severely impact a person's quality of life and daily functioning.

Convulsive Seizures Epidemiology Segmentation:
The Convulsive Seizures market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
Convulsive Seizures Total Prevalence
Convulsive Seizures Prevalent Cases by severity
Convulsive Seizures Gender-specific Prevalence
Convulsive Seizures Diagnosed Cases of Episodic and Chronic

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Convulsive Seizures Market Insights
The global antiepileptic drug market was valued at approximately USD 4.5 billion in 2023 and is expected to grow at a compound annual growth rate (CAGR) of around 5.8% from 2024 to 2030. This growth is driven by increasing diagnosis rates and the rising prevalence of neurological disorders.
Several new therapies, including next-generation antiepileptic drugs and novel neurostimulation devices, are in the pipeline. These innovations target treatment-resistant epilepsy (TLE) and aim to reduce side effects while improving patient quality of life.
North America dominates the market due to advanced healthcare infrastructure, higher diagnosis rates, and an established pharmaceutical industry. Europe follows closely behind, while emerging markets in Asia-Pacific (APAC) are expected to witness significant growth due to improving healthcare access and growing awareness.

Convulsive Seizures Drugs Uptake
Levetiracetam (Keppra): Levetiracetam is one of the most commonly prescribed AEDs due to its favorable side effect profile and efficacy in reducing convulsive seizures. Since its approval, the uptake has been robust across age groups, particularly for patients with partial-onset and tonic-clonic seizures.
Lacosamide (Vimpat): Approved for the treatment of partial-onset seizures, Lacosamide has shown significant uptake in cases where other AEDs fail. Its growing popularity can be attributed to its effectiveness in combination therapy and ability to reduce convulsive seizures with fewer side effects.
Perampanel (Fycompa): Perampanel is a selective AMPA receptor antagonist, effective in controlling both generalized tonic-clonic and partial seizures. Its ability to target drug-resistant seizures has increased its uptake in difficult-to-treat cases. It is often used as an adjunctive treatment when other medications fail to provide adequate control.
(Epidiolex): Epidiolex, derived from, has been a breakthrough treatment, particularly for rare forms of epilepsy like Dravet syndrome and Lennox-Gastaut syndrome.
Brivaracetam (Briviact): A relatively new drug approved for the treatment of partial-onset seizures, Brivaracetam has been gaining traction as an adjunctive therapy, particularly for patients with treatment-resistant convulsive seizures. Its similarity to levetiracetam but with a different mechanism makes it a valuable addition to the treatment arsenal.
Fenfluramine (Fintepla): Approved for Dravet syndrome, Fenfluramine has demonstrated efficacy in significantly reducing convulsive seizures in patients who are resistant to other therapies.

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Convulsive Seizures Therapies and Key Companies:
Ketamine, Midazolam: Sohag University
Levetiracetam: UCB Pharma
IV Ganaxolone active: Marinus Pharmaceuticals
Phenobarbital: University of Cape Town
SHP615: MHOS/SHP615: Shire
EPX-100 (clemizole HCl): Epygenix

Convulsive Seizures Epidemiology:
Convulsive seizures, also known as tonic-clonic seizures, are a hallmark of epilepsy but can also occur due to other neurological conditions. These seizures involve sudden, rhythmic muscle contractions and loss of consciousness, presenting serious health concerns. The epidemiology of convulsive seizures is closely tied to epilepsy, affecting millions of people worldwide.

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Convulsive Seizures Market Drivers:
Rising Awareness: Increasing public and healthcare professional awareness about epilepsy and convulsive seizures is leading to earlier diagnosis and intervention.
Improved Diagnostics: Advances in imaging techniques, such as functional MRI (fMRI) and electroencephalography (EEG), are facilitating earlier and more accurate diagnoses of epilepsy and related convulsive seizures.
Innovative Therapies: Development of novel AEDs, which offer better seizure control with fewer side effects, is a key market driver.
Increasing Disease Prevalence: The growing burden of neurological disorders, including traumatic brain injuries and infections that can trigger seizures, is increasing the incidence of convulsive seizures.

Convulsive Seizures Market Barriers:
Treatment Resistance: Approximately 30% of epilepsy patients are diagnosed with treatment-resistant epilepsy, meaning that current antiepileptic drugs fail to control their seizures effectively.
Side Effects of Antiepileptic Drugs (AEDs): Many first- and second-generation AEDs are associated with significant side effects, including cognitive impairment, mood changes, and drug interactions, leading to treatment discontinuation or non-adherence among some patients.
Stigma and Misunderstanding: Social stigma around epilepsy and convulsive seizures continues to exist in many parts of the world, often preventing people from seeking medical attention or adhering to prescribed treatments.

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Scope of the Convulsive Seizures Market Report:
Study Period: 2019-2032
Coverage: 7MM (The United States, EU5, and Japan)
Key Convulsive Seizures Companies: UCB Pharma, PTC Therapeutics, Shire, Takeda, Marinus Pharmaceuticals, Epygenix
Key Convulsive Seizures Therapies: Ketamine, Midazolam, Levetiracetam, IV Ganaxolone active Phenobarbital, SHP615, MHOS/SHP615, EPX-100 (clemizole HCl)
Convulsive Seizures Therapeutic Assessment: Current marketed and emerging therapies
Convulsive Seizures Market Dynamics: Convulsive Seizures Market drivers and Convulsive Seizures barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Convulsive Seizures Unmet Needs: Insights into unmet needs, KOL's views, Analyst's views, Market Access, and Reimbursement.

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Table of Content:

1. Key Insights
2. Executive Summary of Convulsive Seizures
3. Competitive Intelligence Analysis for Convulsive Seizures
4. Convulsive Seizures: Market Overview at a Glance
5. Convulsive Seizures: Disease Background and Overview
6. Patient Journey
7. Convulsive Seizures Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Convulsive Seizures Unmet Needs
10. Key Endpoints of Convulsive Seizures Treatment
11. Convulsive Seizures Marketed Products
12. Convulsive Seizures Emerging Therapies
13. Convulsive Seizures: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Convulsive Seizures
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

About DelveInsight:
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