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Genome Editing Market Size to Boost USD 25.58 Billion By 2032 | CAGR 15.3% - Published by Emergen Research
Genome Editing Market
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Gene Editing: Transforming Healthcare and Agriculture
Gene editing, a type of gene therapy that alters the DNA sequence in specific cells to treat or prevent genetic conditions, has wide-reaching applications in both healthcare and agriculture. The ability to modify the genomes of plants, animals, and microorganisms has led to innovations that improve crop yield, disease resistance, and food security. Scientists are using gene editing tools to introduce drought resistance and improve the nutritional content of crops, providing solutions to some of the most pressing global challenges.
Biotechnology companies are at the forefront of developing new gene-editing technologies. For instance, Corteva Agriscience has applied CRISPR technology to develop disease-resistant corn varieties, helping North American farmers combat crop diseases.
Addressing Chronic Diseases through Gene Editing
The rise in chronic diseases like cardiovascular disease, cancer, and diabetes is also a significant driver of the gene editing market. Gene editing tools are being used for therapeutic development to address these conditions. In the U.S., millions are affected by diseases such as Alzheimer's and Parkinson's. Innovations like ioCRISPR-Ready Cells from bit.bio are designed to advance research in these areas by providing scientists with tools to study the genetic causes of neurodegenerative diseases.
Governments are also stepping in to promote advancements in this field. The Indian government's Department of Biotechnology has launched initiatives to encourage the use of genome editing in agriculture, further expanding the potential of this technology.
CRISPR-Cas9: Revolutionizing Medical Research and Treatment
One of the most groundbreaking developments in gene editing is the CRISPR-Cas9 technology. This tool allows for precise editing of DNA sequences and has been widely adopted for both research and medical applications. It is being used in the development of personalized treatments for chronic diseases, such as cancer, by providing faster, cheaper, and more accurate methods of gene modification.
CRISPR-based therapies are gaining traction in cardiovascular disease treatment. Companies like CRISPR Therapeutics are leading the way in using this technology to develop new drugs for heart disease. Similarly, Merck's expanded facility in California aims to support gene therapy research by providing viral vector-based delivery systems.
Challenges: Ethical Concerns and Regulatory Hurdles
While the potential of gene editing is vast, it is not without challenges. Ethical concerns surrounding genetic modification, especially in human germline editing, have led to strict regulations that could restrain market growth. Unintended "off-target" effects, where CRISPR makes unintended changes to the genome, are also areas of concern.
Market Insights: CRISPR Leading the Way
The CRISPR segment dominates the gene editing market, accounting for the largest share in 2022. This technology's precision and efficiency make it a preferred method for DNA editing, especially in personalized medicine. Companies like Harpe Bioherbicide Solutions and Corteva Agriscience are utilizing CRISPR for innovative agricultural solutions.
TALEN, another gene editing technology, is also seeing steady growth. Its use in developing disease-resistant crops and improving plant nutrition is gaining attention. Companies like Tropic Biosciences are applying TALEN alongside CRISPR to create non-transgenic disease-resistant traits in crops like corn and soybeans.
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Gene Editing in Clinical Applications
Beyond agriculture, gene editing is making headway in clinical applications, particularly in developing treatments for serious diseases such as cancer and sickle cell anemia. Collaborations between major biotechnology firms, like the one between Precision BioSciences and Novartis, are paving the way for new therapeutic developments.
Biotech Companies at the Helm
The biotechnology and pharmaceutical sectors are expected to continue driving growth in the gene editing market. With the rise in chronic diseases, there is increasing demand for innovative treatments and diagnostic tools. Companies like Regeneron Pharmaceuticals and Intellia Therapeutics are spearheading collaborations to develop advanced CRISPR-based therapies for neurological and muscular diseases.
Genome Editing Top Companies and Competitive Landscape
The global genome editing market is fairly fragmented, with many large and medium-sized players accounting for majority of market revenue. Major players are deploying various strategies, entering into mergers & acquisitions, strategic agreements & contracts, developing, testing, and introducing more effective genome editing solutions.
Some major players included in the global genome editing market report are:
Thermo Fisher Scientific Inc.
Merck KGaA
Lonza
GenScript
Tecan Trading AG
PerkinElmer Inc.
Agilent Technologies, Inc.
CRISPR Therapeutics
Editas Medicine
Cellectis
Sangamo Therapeutics
Precision BioSciences
Intellia Therapeutics, Inc.
bluebird bio, Inc.
Creative Biogene
Synthego
Beam Therapeutics
AMSBIO
Regeneron Pharmaceuticals Inc.
Mammoth Biosciences, Inc.
OriGene Technologies, Inc.
New England Biolabs
Caribou Biosciences, Inc.
Inscripta, Inc.
Integrated DNA Technologies, Inc.
Horizon Discovery Ltd.
Takara Bio Inc.
AstraZeneca
Recombinetics
Cibus Inc.,
Bio-Rad Laboratories, Inc.
Genome Editing Latest Industry Updates
On 1 November 2023, AstraZeneca announced the collaboration and investment agreement with Cellectis, a clinical-stage biotechnology company to develop next generation therapeutic areas such as gene therapy and gene editing for treatment of oncology, immunology and rare diseases.
On 15 February 2022, Intellia Therapeutics, Inc., a major genome editing company that develop curative CRISPR-based therapies and ONK Therapeutics Ltd., an innovative company dedicated to design optimally engineered Natural Killer (NK) cell therapies to cure cancer patients announced the collaboration agreement to advanced allogenic CRISPR-edited NK cell therapies for treatment of patients with cancer.
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For the purpose of this report, Emergen Research has segmented the global genome editing market on the basis of product and services type, technology, delivery method, application, end-use, and region:
Product and Services Type Outlook (Revenue, USD Billion; 2019-2032)
Reagents and Consumables
Software and Systems
Services
Technology Outlook (Revenue, USD Billion; 2019-2032)
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
Transcription Activator-Like Effector Nuclease (TALEN)
Zinc Finger Nuclease (ZFN)
Antisense
Meganucleases
Others
Delivery Method Outlook (Revenue, USD Billion; 2019-2032)
Ex-Vivo
In-Vivo
Application Outlook (Revenue, USD Billion; 2019-2032)
Genetic Engineering
Cell Line Engineering
Animal Genetic Engineering
Plant Genetic Engineering
Gene-modification Cell Therapy
Others
Clinical Applications
Diagnostics Application
Drug Discovery and Development
Therapy Development
End-Use Outlook (Revenue, USD Billion; 2019-2032)
Biotechnology and Pharmaceutical Companies
Academic and Research Institutes
Contract Research Organizations (CROs)
Hospitals
Others
Regional Outlook (Revenue, USD Billion; 2019-2032)
North America
U.S.
Canada
Mexico
Europe
Germany
France
UK
Italy
Spain
Benelux
Rest of Europe
Asia Pacific
China
India
Japan
South Korea
Rest of APAC
Latin America
Brazil
Rest of LATAM
Middle East & Africa
Saudi Arabia
UAE
South Africa
Turkey
Rest of Middle East & Africa
Look Over transcripts provided by Emergen Research
Genome Editing Market Size@ https://www.emergenresearch.com/industry-report/genome-editing-market/market-size
Genome Editing Market Share@ https://www.emergenresearch.com/industry-report/genome-editing-market/market-share
Genome Editing Market Trends@ https://www.emergenresearch.com/industry-report/genome-editing-market/market-trends
Genome Editing Regional Market Demand@ https://www.emergenresearch.com/industry-report/genome-editing-market/regional-market-demand
Genome Editing Market Analysis@ https://www.emergenresearch.com/industry-report/genome-editing-market/market-analysis
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