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Thrombotic Thrombocytopenic Purpura Market Size is Set for Rapid Growth as Innovative Treatments and Rising Awareness Drive Demand by 2034

09-23-2024 05:52 PM CET | Health & Medicine

Press release from: DelveInsight Business Research LLP

Thrombotic Thrombocytopenic Purpura Market

Thrombotic Thrombocytopenic Purpura Market

The Thrombotic Thrombocytopenic Purpura market size is expected to increase during the forecast period with the increasing prevalence, disease awareness, and promising emerging treatment options by leading companies such as Sanofi, Amgen, GlaxoSmithKline, Eisai Inc., Novartis Pharmaceuticals, Rigel Pharmaceuticals, Hoffmann-La Roche, Veralox Therapeutics, Takeda, GlycoMimetics, Inclacumab, Prasugrel, Crovalimab, Sevuparin.

[Nevada, United States] - DelveInsight's "Thrombotic Thrombocytopenic Purpura Market Insights, Epidemiology, and Market Forecast 2034." report offers a detailed examination of Thrombotic Thrombocytopenic Purpura, covering historical and predicted epidemiology, market trends, and treatment scenarios in the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

To Know in detail about the Thrombotic Thrombocytopenic Purpura Market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; https://www.delveinsight.com/report-store/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Key Findings from the Thrombotic Thrombocytopenic Purpura Market Report:
The Thrombotic Thrombocytopenic Purpura market size is poised for significant growth, with an anticipated Compound Annual Growth Rate (CAGR) during the study period (2020-2034).
In September, 2024: Novartis Pharmaceuticals announced that the purpose of their trial is to assess the ability of eltrombopag to induce sustained treatment-free remission in immune thrombocytopenia purpura (ITP) subjects who relapsed or failed to respond to an initial treatment with steroids.
In September, 2024: Novartis Pharmaceuticals announced that their study will evaluate the therapeutic efficacy, safety and tolerability of ianalumab in adult patients with primary ITP previously treated with at least one corticosteroid and one TPO-RA.
In July, 2024: Pfizer announced a Phase 2, open-label, multicenter, multiple subcutaneous injection, safety and efficacy study of PF-06835375 in adult participants with primary immune thrombocytopenia (ITP). This study will focus on participants with persistent (>3 months and ≤12 months), or chronic (>12 months) ITP
In July, 2024: Sanofi announced that a single group, treatment, Phase 3, open-label, single-arm study to evaluate the efficacy and safety of caplacizumab and immunosuppressive therapy (IST) without firstline therapeutic plasma exchange (TPE) with primary endpoint of remission in male and female participants aged 18 to 80 years with immune-mediated thrombotic thrombocytopenic purpura (iTTP).
In July, 2024: Kyowa Kirin Co., Ltd. announced that the aim of their study is to evaluate the efficacy of starting dose of AMG 531 as measured by platelet counts by cohort dose-escalation design.
Mariotte et al. (2016) conducted a study to investigate the association between mechanisms for ADAMTS13deficiency and the epidemiology and pathophysiology of TTP at initial presentation in France. Theresearchers found a prevalence rate of 13 cases per million inhabitants.
Borborema et al. (2020) state that the Oklahoma TTP-HUS registry, representing a population base of 2million people, has identified a family with cTTP every 26 years. The researchers suggested a prevalence of1.5 patients per 1 million inhabitants for cTTP.
Key Thrombotic Thrombocytopenic Purpura Companies are as follows: Sanofi, Amgen, GlaxoSmithKline, Eisai Inc., Novartis Pharmaceuticals, Rigel Pharmaceuticals, Hoffmann-La Roche, Veralox Therapeutics, Takeda, GlycoMimetics, Inclacumab, Prasugrel, Crovalimab, Sevuparin.
Key Thrombotic Thrombocytopenic Purpura Therapies are as follow: Caplacizumab, Corticosteroids, TAK-755, SHP655, Romiplostim, Eltrombopag, Avatrombopag, Eltrombopag, R788, Fostamatinib Disodium / R935788, LGD-4665, Fostamatinib Disodium
Launching multiple stage Thrombotic Thrombocytopenic Purpura pipeline products is expected to revolutionize market dynamics, further propelling market growth.

Dive into our detailed Thrombotic Thrombocytopenic Purpura market research report to uncover actionable insights, industry forecasts, and competitive analysis @ https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Thrombotic Thrombocytopenic Purpura Overview:
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder that causes blood clots (thrombi) to form in small bloodvessels throughout the body. These clots can cause serious medical problems if they block vessels and restrict bloodflow to organs such as the brain, kidneys, and heart. Complications resulting fromthese clots can include neurologicalproblems (such as personality changes, headaches, confusion, and slurred speech), fever, abnormal kidney function,abdominal pain, and heart problems.

Thrombotic Thrombocytopenic Purpura Epidemiology Segmentation:
The Thrombotic Thrombocytopenic Purpura market report proffers epidemiological analysis for the study period 2020-2034 in the 7MM segmented into:
Total Diagnosed Prevalent Cases of Thrombotic Thrombocytopenic Purpura
Gender-specific Diagnosed Prevalent Cases of Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in the 7MM
Age-specific diagnosed Prevalent Cases of Thrombotic Acquired Thrombocytopenic Purpura Type-specific Prevalent Cases of Thrombotic Thrombocytopenic Purpura (TTP) in the 7MM
Gender-specific diagnosed Prevalent Cases of Congenital Thrombotic Thrombocytopenic Purpura (cTTP) in the 7MM Age-specific diagnosed Prevalent Cases of Congenital Thrombotic Acquired Thrombocytopenic Purpura (cTTP) in the 7MM

For more information about Thrombotic Thrombocytopenic Purpura companies working in the treatment market, visit https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Thrombotic Thrombocytopenic Purpura Market Insights
The TTP drug landscape has significantly evolved, especially with the introduction of new targeted therapies. Key treatments currently include plasma exchange (plasmapheresis), immunosuppressants, and targeted biologics like caplacizumab (Cablivi), which has become a critical therapy for treating acquired TTP. The uptake of caplacizumab has transformed the therapeutic landscape by reducing mortality rates and preventing recurrences of thrombotic events.

Thrombotic Thrombocytopenic Purpura Drugs Uptake
Caplacizumab remains the most significant recent breakthrough in the treatment of acquired TTP. As the first and only approved therapy specifically targeting the von Willebrand factor (vWF), caplacizumab has shown remarkable efficacy in reducing the formation of blood clots by inhibiting the interaction between platelets and vWF.
Rituximab, a monoclonal antibody targeting CD20, continues to be a widely adopted off-label treatment, especially in patients with refractory or relapsed TTP. Its success in depleting B-cells and thereby reducing the production of antibodies that inhibit ADAMTS13 has made it a cornerstone in the management of autoimmune TTP.
The combination of plasma exchange with newer therapies like caplacizumab has led to improved treatment outcomes, as plasmapheresis works to remove circulating autoantibodies and replenish ADAMTS13, while caplacizumab reduces clot formation.
Several promising therapies targeting ADAMTS13 enzyme replacement and other novel pathways are in late-stage clinical trials and are anticipated to enter the market soon. These include recombinant ADAMTS13 therapies aimed at restoring enzyme levels in congenital TTP and other advanced immune modulators for acquired TTP.

Dive into our comprehensive market research report to discover in-depth insights, emerging trends, and strategic opportunities @ https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Thrombotic Thrombocytopenic Purpura Therapies and Key Companies:
Caplacizumab, Corticosteroids: Sanofi
TAK-755: Takeda
SHP655: Shire
Romiplostim: Amgen
Eltrombopag: GlaxoSmithKline
Avatrombopag: Eisai Inc.
Eltrombopag: Novartis Pharmaceuticals
R788: Kissei Pharmaceutical Co., Ltd.
Fostamatinib Disodium / R935788: Rigel Pharmaceuticals
LGD-4665: GlaxoSmithKline
Fostamatinib Disodium: Rigel Pharmaceuticals

Thrombotic Thrombocytopenic Purpura Epidemiology:
Though TTP is rare, its precise epidemiology varies by region. The annual incidence of TTP ranges between 1 and 5 cases per million individuals globally, with a slightly higher prevalence among women. The disease is often associated with autoimmune conditions, particularly lupus, and can also be triggered by certain medications or infections. Timely diagnosis remains crucial, as untreated TTP can result in mortality rates exceeding 90%. However, with advancements in therapy, the survival rate has improved significantly, reducing mortality to less than 20% in treated patients.

Seize Market Opportunities with Our Expert Analysis! Our report delivers valuable insights into market dynamics, key players, and emerging trends @ https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Thrombotic Thrombocytopenic Purpura Market Drivers:
Technological Advancements and Novel Drug Approvals
Increased Awareness and Early Diagnosis
Rising R&D Investments
Regulatory Support for Orphan Drugs

Thrombotic Thrombocytopenic Purpura Market Barriers:
High Treatment Costs
Limited Awareness in Developing Regions
Adverse Side Effects of Current Therapies

Stay Ahead in a Competitive Landscape with Our Exhaustive Market Research Report-Dive Into Detailed Analysis, Key Trends, and Future Projections @ https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Scope of the Thrombotic Thrombocytopenic Purpura Market Report:
Study Period: 2020-2034
Coverage: 7MM (The United States, EU5, and Japan)
Key Thrombotic Thrombocytopenic Purpura Companies: Sanofi, Amgen, GlaxoSmithKline, Eisai Inc., Novartis Pharmaceuticals, Rigel Pharmaceuticals, Hoffmann-La Roche, Veralox Therapeutics, Takeda, GlycoMimetics, Inclacumab, Prasugrel, Crovalimab, Sevuparin.
Key Thrombotic Thrombocytopenic Purpura Therapies: Caplacizumab, Corticosteroids, TAK-755, SHP655, Romiplostim, Eltrombopag, Avatrombopag, Eltrombopag, R788, Fostamatinib Disodium / R935788, LGD-4665, Fostamatinib Disodium
Thrombotic Thrombocytopenic Purpura Therapeutic Assessment: Current marketed and emerging therapies
Thrombotic Thrombocytopenic Purpura Market Dynamics: Thrombotic Thrombocytopenic Purpura Market drivers and Thrombotic Thrombocytopenic Purpura barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Thrombotic Thrombocytopenic Purpura Unmet Needs: Insights into unmet needs, KOL's views, Analyst's views, Market Access, and Reimbursement.

To access the full report and gain a deeper understanding of Thrombotic Thrombocytopenic Purpura market outlook, drug uptake, treatment scenario, and epidemiology trends, https://www.delveinsight.com/sample-request/thrombotic-thrombocytopenic-purpura-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rkpr

Table of Content:

1. Key Insights
2. Thrombotic Thrombocytopenic Purpura Executive Summary
3. Competitive Intelligence Analysis for Thrombotic Thrombocytopenic Purpura
4. Thrombotic Thrombocytopenic Purpura: Market Overview at a Glance
5. Thrombotic Thrombocytopenic Purpura Market Disease Background and Overview
6. Patient Journey
7. Thrombotic Thrombocytopenic Purpura Epidemiology and Patient Population
8. Thrombotic Thrombocytopenic Purpura Treatment Algorithm, Current Treatment, and Medical Practices
9. Thrombotic Thrombocytopenic Purpura Unmet Needs
10. Key Endpoints of Thrombotic Thrombocytopenic Purpura Treatment
11. Thrombotic Thrombocytopenic Purpura Marketed Products
12. Thrombotic Thrombocytopenic Purpura Emerging Therapies
13. Thrombotic Thrombocytopenic Purpura: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Thrombotic Thrombocytopenic Purpura Market Outlook
16. Access and Reimbursement Overview of Thrombotic Thrombocytopenic Purpura
17. Thrombotic Thrombocytopenic Purpura KOL Views
18. Thrombotic Thrombocytopenic Purpura Market Drivers
19. Thrombotic Thrombocytopenic Purpura Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight

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