Mice Model Usage Increases in Scope Through Advanced Models

Mouse is a popular model system because it is a mammal with sophisticated genetic tools and significant genetic resources. The prospect of the mice as a model for exploring human pathophysiology and disease progression and for developing drugs is likely to be further widened by the introduction of new models such as immunedeficient and humanizing mouse in which human tissues and cells or genes are reconstituted. With 99% of their genes shared with humans, new possibilities were opened for genetic testing. Furthermore, the conservation of genetic association within the mice and human genomes with respect to the encoded genes and their alignment along chromosomes has been a great advantage in the identification of potentially conforming homologous mutations and disease genes.

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The extremely consolidated global market for mice models is primarily dominated by the players Charles River, The Jackson Laboratory, and Harlan Laboratories – three companies that collectively occupied 75% of the market in 2014 in terms of value.

At the time, the market was predominantly controlled by a small number of players, mostly owing to the disparity in demand between developed and developing economies. However, as the rate of development of emerging economies and their biomedical industries ramps up, so does their demand for mice models.

The resultant effect on the competitive landscape for the global mice models market is a significant growth in the number of regional players in the emerging economies. They pose a direct threat to the globally prominent players that are trying to invest in the opportunities that these regions hold.

According to a new publication by Transparency Market Research, the trend of outsourcing mice models to CROs and pharma companies is also driving the global demand for mice models.

Advancements in Mice Model Types and Services Add to Research Scope and Capabilities

“The ALS Association had recently shown the use of mutated mice models for the study of the disease,” states a TMR analyst. “This is only one of the many examples that can show that the recent advancements in mice model types and services have not only added to the strength of existing research processes, but have also expanded the scope of mice model use within other medical research fields.”

New mice models are found to be acceptable in the studies of advanced diseases, a fact which is greatly driving the demand for mice models. They can now be used in advanced research such as lung disease repair.

The integral nature of the mice models market with the pharmaceutical and biomedical fields has allowed companies from these industries to form alliances that can even revolve around further advancing the mice models types and services in the future.

Growing Scope of Alternative Technologies Restrains Use of Mice Models

A lot of companies are currently seeking non-animal test methods for their research processes in order to either eliminate animal use completely or to restrict it as much as possible. Alternatives include solutions such as the Irritation Assay System which is a simplified procedure in a test tube used for skin irritation, or even human skin culture.

A lot of these alternatives are not only cheaper but also provide a faster and more accurate conclusion formation process. This complements the reduction in use of animal models due to the growing protests by people against their use.

In another alternative, professionals are adopting computer-generated simulations to test their processes, further reducing the need for animal models.

North America Retains Leading Demand for Mice Models While APAC Demand Soars

The global market for mice models is expected to be evaluated at US$1.79 bn by the end of 2023.

North America has consistently been a key region in terms of demand for mice models. By the end of 2023, this region is expected to generate a revenue of US$785.4 mn. Meanwhile, the demand for mice models is expected to expand at a CAGR of 11.1% in Asia Pacific, from 2015 to 2023.

An immense demand for genetically engineered mice models is expected to put this service type in the leading position by 2023, with an expected revenue of US$155.2 mn. Mouse breeding and re-derivation have so far been the more popular mice model service types but are likely to be replaced by genetically engineered models soon.

Inbred mice models have consistently been the more popular mice model types. By the end of 2023, the revenue earned by the inbred mice model segment is expected to reach US$340.6 mn.

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This release was published on openPR.