Acute Myeloid Leukemia Pipeline Insights, Treatment Drugs, Clinical Trials and Companies 2024

DelveInsight's, "Acute Myeloid Leukemia Pipeline Insight 2024" report provides comprehensive insights about 150+ companies and 150+ pipeline drugs in the Acute Myeloid Leukemia pipeline landscape. It covers the Acute Myeloid Leukemia pipeline drug profiles, including Acute Myeloid Leukemia clinical trials and nonclinical stage products. It also covers the Acute Myeloid Leukemia pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Request a sample and discover the recent advances in Acute Myeloid Leukemia Treatment Drugs @ Acute Myeloid Leukemia Infection Pipeline Outlook Report- https://www.delveinsight.com/report-store/acute-myeloid-leukemia-aml-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Key Takeaways from the Acute Myeloid Leukemia Pipeline Report
• In September 2024:- Taiho Oncology Inc.- The primary purpose of the study is to rule out drug-drug interactions between ASTX727 and venetoclax combination therapy by evaluating area under the curve (AUC) and maximum plasma concentration (Cmax) exposure. The Phase 2 portion of the study is to assess the efficacy of ASTX727 and venetoclax when given in combination and to evaluate potential PK interactions. Phase 2 will follow the same overall study design as Phase 1 and has two parts, Part A and Part B.
• In August 2024:- Novartis Pharmaceuticals- The primary purpose of this study is to test the hypothesis that preemptive treatment with sabatolimab, alone or in combination with azacitidine, when administered to participants with AML/secondary AML who are in complete remission with positive measurable residual disease post-allogeneic hematopoietic stem cell transplantation (MRD+ post-aHSCT), can enhance the graft versus leukemia (GvL) response and prevent or delay hematologic relapse without an unacceptable level of treatment-emergent toxicities, including clinically significant acute and/or chronic graft-versus-host disease (GvHD) and immune-related adverse events
• DelveInsight's Acute Myeloid Leukemia pipeline report depicts a robust space with 150+ active players working to develop 150+ pipeline therapies for Acute Myeloid Leukemia treatment.
• The leading companies working in the Acute Myeloid Leukemia market include GlycoMimetics, CSPC ZhongQi Pharmaceutical Technology Co., Ltd., Takeda Oncology, Orca Bio, Gilead Sciences, Actinium Pharmaceuticals, Kronos Bio, Bristol-Myers Squibb, ImmunityBio, Bellicum Pharmaceuticals, TC BioPharm, Syros Pharmaceuticals, Armaceutica, Teva Pharmaceutical Industries, New Epsilon Innovation Limited, MediGene, TC Biopharm, PersonGen BioTherapeutics, Oncoceutics, Janssen Research & Development, LLC, Immune-Onc Therapeutics, Novartis, Jasper Therapeutics, Agastiya Biotech, Poseida Therapeutics, Molecular Partners, Allogene Therapeutics, Allogene therapeutics, and others.
• Promising Acute Myeloid Leukemia Pipeline Therapies in the various stages of development include OCV-501, SEL24/MEN1703, Venetoclax, Alvocidib, TL-895, KRT-232, XY0206, Azacitidine, Venetoclax, and others.

Find out more about Acute Myeloid Leukemia Treatment Drugs @ Drugs for Acute Myeloid Leukemia Treatment- https://www.delveinsight.com/sample-request/acute-myeloid-leukemia-aml-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

The Acute Myeloid Leukemia pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage Acute Myeloid Leukemia drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the Acute Myeloid Leukemia clinical trial landscape. Acute myeloid leukemia (AML) is the most common leukemia among the adult population and accounts for about 80% of all cases. It is characterized by clonal expansion of immature "blast cells" in the peripheral blood and bone marrow resulting in ineffective erythropoiesis and bone marrow failure.

Acute Myeloid Leukemia Emerging Drugs Profile

• BST-236: BioSight
Aspacytarabine (BST-236) is a novel proprietary anti-metabolite. It is composed of cytarabine covalently bound to asparagine, acting as a pro-drug of cytarabine, enabling delivery of high cytarabine doses to leukemia patients with lower systemic exposure to the free drug. The drug is currently in phase II stage of of clinical trial evaluation for the treatment of Acute Myeloid Leukemia (AML).

• Uproleselan: GlycoMimetics
GlycoMimetics is developing uproleselan, a specific E-selectin antagonist, to be used in combination with chemotherapy to treat patients with Acute Myeloid Leukemia (AML) (AML) and potentially other hematologic cancers. Uproleselan is designed to bind to E-selectin and block the normal processes controlled by E-selectin. E-selectin is expressed on the surface of blood vessels, and its binding to myeloid cells confers a pro-survival effect via NF-kB signaling. Uproleselan is designed to provide a novel approach to disrupting established mechanisms of leukemic cell resistance. It is believed that by binding to E-selectin, uproleselan pushes AML cells out of their protective niche, blocks cellular communication signals that promote survival, and sensitizes cancer cells to the toxic effects of chemotherapy. The drug is currently in phase III stage of clinical trial evaluation for the treatment of Acute Myeloid Leukemia (AML).

• MK-0482: Merck Sharp & Dohme LLC
MK-0482, a novel humanized IgG4 mAb targeting ILT3, is undergoing phase I evaluation ±pembrolizumab (pembro) in advanced solid tumors. MK-0482 ± pembro was generally well tolerated, and combination therapy provided modest antitumor activity in patients with heavily pretreated advanced solid tumors. The RP2D of MK-0482 + pembro is under further evaluation in tumor-specific cohorts.

Learn more about the emerging Acute Myeloid Leukemia Pipeline Therapies @ Acute Myeloid Leukemia Clinical Trials Assessment- https://www.delveinsight.com/sample-request/acute-myeloid-leukemia-aml-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Acute Myeloid Leukemia Pipeline Therapeutics Assessment
There are approx. 150+ key companies which are developing the Acute Myeloid Leukaemia therapies. The Acute Myeloid Leukaemia companies which have their Acute Myeloid Leukaemia drug candidates in the most advanced stage, i.e preregistration include Gamida Cell.

The Acute Myeloid Leukaemia pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Intravenous
• Subcutaneous

Acute Myeloid Leukaemia Pipeline Products have been categorized under various Molecule types such as
• Small molecule
• Cell Therapy
• Peptides
• Polymer
• Small molecule
• Gene therapy

Dive deep into rich insights for new drugs for Acute Myeloid Leukemia treatment, Visit @ Acute Myeloid Leukemia Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/acute-myeloid-leukemia-aml-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Acute Myeloid Leukemia Pipeline Report
• Coverage- Global
• Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Acute Myeloid Leukemia Companies- GlycoMimetics, CSPC ZhongQi Pharmaceutical Technology Co., Ltd., Takeda Oncology, Orca Bio, Gilead Sciences, Actinium Pharmaceuticals, Kronos Bio, Bristol-Myers Squibb, ImmunityBio, Bellicum Pharmaceuticals, TC BioPharm, Syros Pharmaceuticals, Armaceutica, Teva Pharmaceutical Industries, New Epsilon Innovation Limited, MediGene, TC Biopharm, PersonGen BioTherapeutics, Oncoceutics, Janssen Research & Development, LLC, Immune-Onc Therapeutics, Novartis, Jasper Therapeutics, Agastiya Biotech, Poseida Therapeutics, Molecular Partners, Allogene Therapeutics, Allogene therapeutics, and others.
• Acute Myeloid Leukemia Pipeline Therapies- OCV-501, SEL24/MEN1703, Venetoclax, Alvocidib, TL-895, KRT-232, XY0206, Azacitidine, Venetoclax, and others.

For further information on the Acute Myeloid Leukemia pipeline therapeutics, reach out @ Acute Myeloid Leukemia Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/acute-myeloid-leukemia-aml-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Acute Myeloid Leukaemia: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Acute Myeloid Leukaemia- DelveInsight's Analytical Perspective
7. Late Stage Products (Preregistration)
8. Omidubicel: Gamida Cell
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase III)
11. Uproleselan: GlycoMimetics
12. Drug profiles in the detailed report…..
13. Mid Stage Products (Phase II)
14. ALT 803: ImmunityBio
15. Early Stage Products (Phase I)
16. JNJ-75276617: Janssen Research & Development, LLC
17. Drug profiles in the detailed report…..
18. Preclinical Stage Products
19. AB001: Agastiya Biotech
20. Drug profiles in the detailed report…..
21. Inactive Products
22. Acute Myeloid Leukaemia Key Companies
23. Acute Myeloid Leukaemia Key Products
24. Acute Myeloid Leukaemia- Unmet Needs
25. Acute Myeloid Leukaemia- Market Drivers and Barriers
26. Acute Myeloid Leukaemia- Future Perspectives and Conclusion
27. Acute Myeloid Leukaemia Analyst Views
28. Acute Myeloid Leukaemia Key Companies
29. Appendix

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