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Bispecific Antibody Clinical Trials 2024: FDA Approvals, Medications, Pipeline, Therapies, Mechanism of Action, Route of Administration by DelveInsight | Janssen, Amgen, Akeso, Zymeworks, Roche, IGM Biosciences, MacroGenics, Provention Bio
Bispecific Antibody Clinical Trials
Key Takeaways from the Bispecific Antibody Competitive Landscape Report
• DelveInsight's Bispecific Antibody report depicts a robust space with 250+ active players working to develop 300+ pipeline therapies for Bispecific Antibody treatment.
• The leading companies working in the Bispecific Antibody Competitive landscape include Janssen, Amgen, Akeso, Zymeworks, Roche, IGM Biosciences, MacroGenics, Provention Bio, Jiangsu Alphamab Biopharmaceuticals, Sichuan Baili Pharmaceutical, Regeneron Pharmaceuticals, Boehringer Ingelheim, and others.
• Promising Bispecific Antibody Therapies in the various stages of development include SI-B003, AK104, Bevacizumab, Paclitaxel, AK112, LY3434172, CDX-527, Etoposide, Carboplatin, and others.
• December 2023: Hoffmann-La Roche, An Open Label, Multicenter, Dose Escalation, Phase 1 & 2 Clinical Study to Evaluate Safety/Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-Tumor Activity of RO7247669, a PD1-LAG3 Bispecific Antibody, in Patients With Advanced and/or Metastatic Solid Tumors.
• December 2023: Janssen Research & Development Inc. announced a study of Phase 1 clinical trials for Teclistamab (IV). The purpose of this study is to identify the recommended Phase 2 dose(s) (RP2Ds) and schedule assessed to be safe for Teclistamab and to characterize the safety and tolerability of Teclistamab at the RP2Ds.
Request a sample and discover the recent advances in Bispecific Antibody Drugs @ Bispecific Antibody Competitive Landscape Report- https://www.delveinsight.com/report-store/bispecific-antibody-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
The Bispecific Antibody competitive landscape report provides an in-depth commercial assessment of drugs that have been included, which comprises collaboration, agreement, licensing, and acquisition - deal values trends. The sub-segmentation is described in the Bispecific Antibody report which provides company-company collaboration (licensing/partnering), company academic collaboration, and acquisition analysis in tabulated form.
Bispecific Antibody Overview
Bispecific antibodies (BsAbs) are engineered proteins that can simultaneously bind to two different antigens or epitopes. This dual specificity allows for novel therapeutic mechanisms, particularly in cancer immunotherapy and other complex diseases. Bispecific antibodies are designed to bring immune cells, such as T-cells, into close proximity with cancer cells, thereby enhancing the immune response against tumors.
The structure of Bispecific antibodies typically involves combining the binding domains of two different antibodies into a single molecule. This can be achieved through various engineering techniques, including the fusion of antibody fragments or the design of novel scaffolds. The result is a versatile therapeutic agent that can target multiple pathways or cell types simultaneously.
One common application of Bispecific antibodies is in redirecting immune cells to cancer cells. For example, one arm of the Bispecific antibodies might bind to a tumor-associated antigen, while the other arm binds to a receptor on T-cells, such as CD3. This bridging effect activates the T-cells, leading to targeted killing of the cancer cells.
Bispecific antibodies are also being explored for use in other diseases, including infectious diseases and autoimmune disorders. Their ability to modulate complex biological processes makes them a promising class of biotherapeutics, with several Bispecific antibodies currently in clinical trials and some already approved for clinical use.
Find out more about Bispecific Antibody Analytical Perspective: In-depth Commercial Assessment @ Bispecific Antibody Collaboration Analysis by Companies- https://www.delveinsight.com/sample-request/bispecific-antibody-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Bispecific Antibody Companies and Product Profile
• Akeso: Ivonescimab
• Zymeworks: Zanidatamab
• Roche: Glofitamab
• IGM Biosciences: Imvotamab
• MacroGenics: MGD024
Bispecific Antibody Competitive Landscape
The Bispecific Antibody competitive landscape report comprises of comparative assessment of Companies (by therapy, development stage, and technology).
Bispecific Antibody Report Assessment
• Bispecific Antibody Company Analysis
• Bispecific Antibody Therapeutic Assessment
• Bispecific Antibody Pipeline Assessment
• Inactive drugs assessment
• Bispecific Antibody Unmet Needs
Learn more about the emerging Bispecific Antibody Competitive Landscape @ Bispecific Antibody Market Drivers and Barriers, Unmet Needs- https://www.delveinsight.com/sample-request/bispecific-antibody-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Scope of the Bispecific Antibody Report
• Coverage- Global
• Bispecific Antibody Therapeutics Assessment: Product Type, Stage and Product Type, Route of Administration, Molecule Type
• Bispecific Antibody Companies- Janssen, Amgen, Akeso, Zymeworks, Roche, IGM Biosciences, MacroGenics, Provention Bio, Jiangsu Alphamab Biopharmaceuticals, Sichuan Baili Pharmaceutical, Regeneron Pharmaceuticals, Boehringer Ingelheim, and others.
• Bispecific Antibody Therapies- SI-B003, AK104, Bevacizumab, Paclitaxel, AK112, LY3434172, CDX-527, Etoposide, Carboplatin, and others.
Dive deep into rich insights for new drugs for Bispecific Antibody Product Developmental Activities, Visit @ Bispecific Antibody Research and Development Activities- https://www.delveinsight.com/sample-request/bispecific-antibody-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Table of Content
1. Introduction
2. Executive Summary
3. Bispecific antibody: Overview
4. Bispecific Antibody -Analytical Perspective: In-depth Commercial Assessment
5. Competitive Landscape
6. Therapeutic Assessment
7. Bispecific antibody: Company and Product Profiles (Marketed Therapies)
8. Janssen
9. Amivantamab
10. Bispecific antibody: Company and Product Profiles (Pipeline Therapies)
11. Late Stage Products (Phase III)
12. Akeso
13. Ivonescimab
14. Drug profiles in the detailed report…..
15. Mid Stage Products (Phase II)
16. IGM Biosciences
17. Imvotamab
18. Drug profiles in the detailed report…..
19. Early Stage Products (Phase I)
20. MacroGenics
21. MGD024
22. Drug profiles in the detailed report…..
23. Preclinical and Discovery Stage Products
24. Company Name
25. Product Name
26. Drug profiles in the detailed report…..
27. Inactive Products
28. Bispecific antibody- Unmet needs
29. Bispecific antibody - Market drivers and barriers
30. Appendix
For further information on the Bispecific Antibody Report @ Bispecific Antibody Preclinical and Discovery Stage Products- https://www.delveinsight.com/sample-request/bispecific-antibody-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
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