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๐๐ซ๐๐๐ญ๐ฆ๐๐ง๐ญ-๐๐๐ฌ๐ข๐ฌ๐ญ๐๐ง๐ญ ๐๐๐ฉ๐ซ๐๐ฌ๐ฌ๐ข๐จ๐ง ๐๐๐ซ๐ค๐๐ญ ๐๐๐ฉ๐จ๐ซ๐ญ, ๐๐ข๐ณ๐, ๐๐ก๐๐ซ๐ & ๐๐ฎ๐ญ๐ฅ๐จ๐จ๐ค - ๐๐๐๐-
๐๐ซ๐๐๐ญ๐ฆ๐๐ง๐ญ-๐๐๐ฌ๐ข๐ฌ๐ญ๐๐ง๐ญ ๐๐๐ฉ๐ซ๐๐ฌ๐ฌ๐ข๐จ๐ง ๐๐๐ซ๐ค๐๐ญ || 2024-2031
Treatment-Resistant Depression (TRD) refers to a form of major depressive disorder (MDD) in which patients do not respond adequately to standard treatments, such as antidepressants or psychotherapy. Typically, a person is considered to have TRD when they have tried at least two different antidepressant medications, each for an adequate duration and dosage, without experiencing significant improvement in their symptoms. This condition requires more intensive treatment strategies, which may include a combination of medications, electroconvulsive therapy (ECT), or newer treatments like transcranial magnetic stimulation (TMS) or ketamine therapy.
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Key Developments:
โ August 19, 2022: The U.S. FDA approved AUVELITYโข (dextromethorphan HBr-bupropion HCl) extended-release tablets for the treatment of major depressive disorder (MDD) in adults.
โข Developed by Axsome Therapeutics, Inc., a biopharmaceutical company focused on therapies for central nervous system (CNS) disorders.
โ January 30, 2023: Otsuka Pharmaceutical Co., Ltd. submitted a Japanese application for Rexulti (brexpiprazole) as an adjunct therapy for MDD and depressive states.
โข This application is limited to patients who have not responded well to prior antidepressant therapy.
โข A phase 3 clinical trial involving 740 adult MDD patients in Japan (ages 20-64) demonstrated the safety and efficacy of brexpiprazole as an additional treatment.
Market Dynamics:
โ Developed economies have seen rapid growth in healthcare sectors due to high investments, income levels, and infrastructure development.
โ Rising cases of treatment-resistant depression (TRD) are linked to increased lung cancer cases in some regions.
โ Collaborations, acquisitions, and product launches with technological advancements are key drivers of market growth.
Market Segmentation:
By Drugs: Antipsychotics (Aripiprazole (Abilify), Brexpiprazole (Rexulti), Quetiapine (Seroquel), Olanzapine (Zyprexa), Selective Serotonin Reuptake Inhibitors (SSRIs) (Fluoxetine (Prozac), Sertraline (Zoloft), Citalopram (Celexa), Paroxetine (Paxil), Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs) (Duloxetine (Cymbalta), Venlafaxine (Effexor XR), Desvenlafaxine (Pristiq), Monoamine Oxidase Inhibitors (MAOIs) (Phenelzine (Nardil), Isocarboxazid (Marplan), Others.
By Route of Administration: Oral, Injectable, Others.
By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies.
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Major Key Players:
โข Pfizer Inc.
โข Viatris Inc.
โข Novartis AG
โข AbbVie Inc.
โข Eli Lilly and Company
โข Otsuka America Pharmaceutical, Inc.
โข AstraZeneca
โข Camber Pharmaceuticals, Inc.
โข Biodesix
โข Validus Pharmaceuticals
*Note:
โข Additionally, I wanted to highlight that the full version of the report includes an in-depth analysis of emerging players and startups, which will provide valuable insights into the evolving market landscape and key strategies being adopted.
Related Reports:
Psychedelic Drugs Market: https://datamintelligence.com/research-report/psychedelic-drugs-market
Psychotherapeutic Drugs Market: https://datamintelligence.com/research-report/psychotherapeutic-drugs-market
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