Fluorescent in Situ Hybridization (FISH) Probe Market Size, Share, Report 2024-2031

The Global "Fluorescent in Situ Hybridization (FISH) Probe Market" is Expected to reach at a CAGR of 8.9% during the forecast period (2024-2031).

Fluorescent in situ hybridization (FISH) is a molecular cytogenetic technique used to visualize and identify genetic components within an individual's cells using fluorescent probes. These probes bind to specific DNA or RNA sequences and emit light when exposed to a specific wavelength, allowing researchers to detect structural and numerical chromosome abnormalities, assess treatment effects, and diagnose rare genetic disorders.

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Market Dynamics:

Advancement in fluorescent in Situ Hybridization (FISH) probe is expected to drive market growth.

Detecting and imaging RNA at the single-cell level is crucial for both basic research and clinical diagnostics. Traditional RNA analysis techniques, such as fluorescence in situ hybridization (FISH), are often time-consuming, complex, and expensive. Amplified FISH (AmpliFISH) offers a solution by using small, ultrabright dye-loaded polymeric nanoparticles (NPs) functionalized with DNA to simplify and accelerate RNA imaging.

AmpliFISH reduces nonspecific intracellular interactions by selecting the appropriate DNA-NP polymer matrix and employs a straightforward 1-hour staining process. This method allows for sequence-specific imaging of various mRNA targets, such as survivin, actin, and polyA tails. It also enables the simultaneous multiplexed detection of three mRNA targets, revealing distinct expression profiles in different cancer cell lines.

AmpliFISH has been shown to be semiquantitative and correlates well with RT-qPCR. It delivers 8-200 times greater signal intensity compared to commercial locked nucleic acid (LNA)-based FISH techniques and involves only three steps instead of 20, significantly reducing processing time. By combining bright fluorescent polymeric NPs with FISH, AmpliFISH provides a rapid and sensitive method for single-cell transcriptomic analysis, advancing RNA research and clinical diagnostics.

Segment Covered in the Fluorescent in Situ Hybridization (FISH) Probe Market:

By Probe Type: Locus Specific Probes, Alphoid or Centromeric Repeat Probes, Whole Chromosome Probes.

By Technology: Q- Fluorescent In Situ Hybridization, FLOW Fluorescent In Situ Hybridization, C- Fluorescent In Situ Hybridization, D- Fluorescent In Situ Hybridization, Other.

By Type: DNA, RNA.

By Application: Cancer Research, Genetic Diseases, Others.

By End-user: Research Organizations*, Biotechnology Companies, Clinical Organizations, Academic and Research Institutes, Others.

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Key players involved in Fluorescent in Situ Hybridization (FISH) Probe Market:

• ThermoFisher Scientific Inc.
• Agilent Technologies
• Genemed Technologies Inc.
• MetaSystems Probes.
• CytoTest Inc.
• Creative Biolabs
• Abbott Molecular Inc
• Oxford Gene Technology IP Ltd.
• Sigma-Aldrich Solutions
• Empire Genomics, Inc.

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Regional Analysis:

The global Fluorescent in Situ Hybridization (FISH) Probe Market report focuses on six major regions: North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa. The report offers detailed insight into new product launches, new technology evolutions, innovative services, and ongoing R&D. The report discusses a qualitative and quantitative market analysis, including PEST analysis, SWOT analysis, and Porter's five force analysis. The Fluorescent in Situ Hybridization (FISH) Probe Market report also provides fundamental details such as raw material sources, distribution networks, methodologies, production capacities, industry supply chain, and product specifications.

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