Press release
Diabetic Macular Edema Clinical Trials | A Drug Pipeline Analysis Report 2024 | Mylan Pharmaceuticals, Kodiak sciences, Celltrion, and others
Diabetic Macular Edema Clinical Trials | A Drug Pipeline Analysis Report 2024
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Key Takeaways from the Diabetic Macular Edema Pipeline Report
Over 65+ Diabetic Macular Edema pipeline therapies are in various stages of development, and their anticipated acceptance in the Diabetic Macular Edema market would significantly increase market revenue.
Leading Diabetic Macular Edema companies developing novel drug candidates to improve the Diabetic Macular Edema treatment landscape include Mylan Pharmaceuticals, Kodiak sciences, Celltrion, and others.
Promising Diabetic Macular Edema pipeline therapies in various stages of development include MYL-1701P, KSI-301, CT-P42, and others.
Diabetic Macular Edema Overview
Diabetic macular edema (DME) is a complication of diabetic retinopathy, a condition affecting the eyes due to diabetes mellitus. It occurs when fluid leaks into the macula, a part of the retina responsible for central vision. Here's an overview covering its causes, signs and symptoms, diagnosis, and treatment options:
Diabetic Macular Edema Causes:
Diabetic macular edema develops primarily due to changes in the blood vessels of the retina caused by diabetes. The underlying mechanisms include:
1. Damage to blood vessels: High blood sugar levels over time can damage the small blood vessels (capillaries) in the retina, leading to leakage of fluid and blood into the surrounding tissues.
2. Increased vascular permeability: Diabetes can cause dysfunction of the blood-retinal barrier, allowing fluid to leak into the macula.
3. Inflammation: Chronic inflammation in the retina may contribute to the development and progression of macular edema.
Diabetic Macular Edema Signs and Symptoms:
1. Blurred or distorted central vision: DME primarily affects central vision, making it difficult to see fine details or causing objects to appear distorted.
2. Decreased color perception: Colors may appear less vibrant or washed out.
3. Floaters: Dark spots or lines that appear to float across the field of vision.
4. Visual disturbances: Difficulty reading, recognizing faces, or performing tasks that require sharp central vision.
Diabetic Macular Edema Diagnosis:
1. Dilated eye exam: An ophthalmologist or optometrist will examine the retina using specialized instruments after dilating the pupil to detect signs of diabetic retinopathy and macular edema.
2. Optical coherence tomography (OCT): This imaging test provides detailed cross-sectional images of the retina, helping to visualize the thickness of the macula and detect any fluid accumulation.
3. Fluorescein angiography: In some cases, a dye is injected into a vein in the arm, and photographs of the retina are taken as the dye circulates. This helps identify areas of leakage from blood vessels in the retina.
Diabetic Macular Edema Treatment Options:
The management of diabetic macular edema aims to reduce swelling in the macula, preserve vision, and prevent further progression of the disease:
1. Intravitreal injections:
- Anti-VEGF therapy: Drugs like ranibizumab (Lucentis), aflibercept (Eylea), or bevacizumab (Avastin) are injected into the vitreous cavity of the eye to block vascular endothelial growth factor (VEGF), a protein that promotes abnormal blood vessel growth and leakage.
- Corticosteroids: Steroid medications such as dexamethasone (Ozurdex) or fluocinolone acetonide (Iluvien) may be injected to reduce inflammation and fluid accumulation in the macula.
2. Laser photocoagulation: Focal laser treatment (photocoagulation) may be used to seal leaking blood vessels and reduce fluid accumulation in the macula. This approach is less commonly used now with the advent of anti-VEGF therapies.
3. Surgery: In severe cases of DME that do not respond to other treatments, vitrectomy surgery may be considered to remove blood and scar tissue from the eye, allowing better penetration of medications.
4. Control of systemic factors: Optimizing diabetes management, controlling blood sugar levels, blood pressure, and cholesterol levels is essential to reduce the risk of progression of diabetic retinopathy and DME.
Diabetic Macular Edema Market Outlook:
The prognosis for diabetic macular edema varies depending on the severity of the condition, the timing of diagnosis, and the effectiveness of treatment. Early detection and timely intervention can significantly improve outcomes and help preserve vision. Regular eye exams and adherence to treatment recommendations are crucial for managing DME and preventing vision loss in individuals with diabetes.
To know more about Diabetic Macular Edema, visit: https://www.delveinsight.com/report-store/diabetic-macular-edema-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Diabetic Macular Edema Pipeline Analysis: Drug Profile
MYL-1701P: Mylan Pharmaceuticals
MYL-1701P (also referred to as M710, as part of a partnership with Momenta Pharmaceuticals) is perhaps the aflibercept biosimilar that is furthest along in the development process. It is currently the subject of a 324-patient phase III trial. Mylan is to handle development and commercialization.
Discover more about the emerging Diabetic Macular Edema drugs @ https://www.delveinsight.com/sample-request/diabetic-macular-edema-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Diabetic Macular Edema Key Companies
Mylan Pharmaceuticals
Kodiak sciences
Celltrion
Diabetic Macular Edema Pipeline Therapies
MYL-1701P
KSI-301
CT-P42
Diabetic Macular Edema Pipeline Therapeutics Assessment
By development stage
By product type
By route of administration
By molecule type
By MOA type
Scope of the Diabetic Macular Edema Pipeline Report
Coverage: Global
Key Diabetic Macular Edema Companies: Mylan Pharmaceuticals, Kodiak sciences, Celltrion, and others
Key Diabetic Macular Edema Pipeline Therapies: MYL-1701P, KSI-301, CT-P42, and others
Find out more about the Diabetic Macular Edema treatment options in development @ https://www.delveinsight.com/sample-request/diabetic-macular-edema-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Table of Contents
1. Introduction
2. Executive Summary
3. Overview
4. Pipeline Therapeutics
5. Late-Stage Products (Phase III)
6. Mid-Stage Products (Phase II)
7. Early Stage Products (Phase I/II)
8. Preclinical Stage Products
9. Discovery Stage Products
10. Therapeutic Assessment
11. Inactive Products
12. Collaborations Assessment- Licensing / Partnering / Funding
13. Unmet Needs
14. Market Drivers and Barriers
15. Appendix
16. About DelveInsight
Download a sample report: @ https://www.delveinsight.com/sample-request/diabetic-macular-edema-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
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