Leukocyte Adhesion Deficiency Treatment Market 2034: FDA Approvals, Clinical trials, Therapies, Prevalence and Companies by DelveInsight | Rocket Pharmaceuticals, Inc., Orpha Labs

(Albany, USA) DelveInsight's "Leukocyte Adhesion Deficiency Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the Leukocyte Adhesion Deficiency, historical and forecasted epidemiology as well as the Leukocyte Adhesion Deficiency market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Leukocyte Adhesion Deficiency market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Leukocyte Adhesion Deficiency pipeline products will significantly revolutionize the Leukocyte Adhesion Deficiency market dynamics.

To Know in detail about the Leukocyte Adhesion Deficiency market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Leukocyte Adhesion Deficiency Market Insights
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Some of the key facts of the Leukocyte Adhesion Deficiency Market Report:
• The Leukocyte Adhesion Deficiency market size is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In February 2024, Rocket Pharmaceuticals, Inc. (NASDAQ: RCKT), a fully integrated biotechnology company dedicated to advancing a comprehensive pipeline of genetic therapies for rare diseases with significant unmet needs, announced today that the U.S. Food and Drug Administration (FDA) has prolonged the Priority Review duration for the Biologics License Application (BLA) for KRESLADI™ (marnetegragene autotemcel) intended for severe Leukocyte Adhesion Deficiency-I (LAD-I). The FDA extended the review timeline by three months, now scheduled until June 30, 2024, to accommodate the assessment of additional Chemistry, Manufacturing, and Controls (CMC) data submitted by Rocket in response to FDA inquiries. Additionally, the FDA has confirmed that there is no necessity for an advisory committee meeting.
• Among the 7MM countries the highest cases of Leukocyte Adhesion Deficiency were found to be in the United States
• The life expectancy of individuals with LAD-I is often severely shortened. Due to repeated infections, affected individuals may not survive past infancy
• According to National Organization for Rare Disorders (NORD, 2022), LAD-I is by far the most common form of the disorder, accounting for hundreds of patients reported from all over the world
• Key Leukocyte Adhesion Deficiency Companies: Rocket Pharmaceuticals, Inc., Orpha Labs, and others
• Key Leukocyte Adhesion Deficiency Therapies: RP-L201, ORL-101, and others

Leukocyte Adhesion Deficiency Overview
Leukocyte Adhesion Deficiency (LAD) is a rare, inherited immunodeficiency disorder characterized by the inability of white blood cells (leukocytes) to properly adhere to blood vessel walls and migrate to sites of infection. This defect in cell adhesion is caused by mutations in genes responsible for producing proteins known as integrins, which are essential for leukocyte attachment and movement.
There are three types of LAD: Type I, Type II, and Type III. Type I Leukocyte Adhesion Deficiency, the most common, results from mutations in the ITGB2 gene, affecting the production of the CD18 integrin subunit. Type II Leukocyte Adhesion Deficiency is caused by defects in the SLC35C1 gene, impacting the fucose transport essential for selectin-mediated leukocyte rolling. Type III Leukocyte Adhesion Deficiency, the rarest form, results from mutations affecting the integrin activation process, impeding both leukocyte and platelet functions.
Individuals with Leukocyte Adhesion Deficiency suffer from recurrent bacterial and fungal infections, often beginning shortly after birth. These infections typically involve the skin, respiratory tract, and gastrointestinal system. Symptoms include delayed wound healing, gum inflammation, and persistent bacterial infections without pus formation.
Leukocyte Adhesion Deficiency Diagnosis is typically made through genetic testing and flow cytometry, which measures the presence of integrins on leukocytes. Leukocyte Adhesion Deficiency Treatment often involves antibiotics to manage infections, with hematopoietic stem cell transplantation offering a potential cure for severe cases. Advances in gene therapy are also being explored as a long-term treatment option.

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Leukocyte Adhesion Deficiency Market
The dynamics of the Leukocyte Adhesion Deficiency market are anticipated to change in the coming years owing to the expected launch of emerging therapies and others during the forecasted period 2019-2032.
"The pipeline for leukocyte adhesion deficiency (LAD) consists of key assets likeRP-L201and ORL-101, among others which, after the expected successful launch, will lead to market growth during the forecast period."

Leukocyte Adhesion Deficiency Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Leukocyte Adhesion Deficiency Epidemiology Segmentation:
The Leukocyte Adhesion Deficiency market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Leukocyte Adhesion Deficiency
• Prevalent Cases of Leukocyte Adhesion Deficiency by severity
• Gender-specific Prevalence of Leukocyte Adhesion Deficiency
• Diagnosed Cases of Episodic and Chronic Leukocyte Adhesion Deficiency

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Leukocyte Adhesion Deficiency Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Leukocyte Adhesion Deficiency market or expected to get launched during the study period. The analysis covers Leukocyte Adhesion Deficiency market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Leukocyte Adhesion Deficiency Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

To know more about Leukocyte Adhesion Deficiency treatment, visit @ Leukocyte Adhesion Deficiency Medications
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Leukocyte Adhesion Deficiency Therapies and Key Companies
• RP-L201: Rocket Pharmaceuticals, Inc.
• ORL-101: Orpha Labs

Scope of the Leukocyte Adhesion Deficiency Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Leukocyte Adhesion Deficiency Companies: Rocket Pharmaceuticals, Inc., Orpha Labs, and others
• Key Leukocyte Adhesion Deficiency Therapies: RP-L201, ORL-101, and others
• Leukocyte Adhesion Deficiency Therapeutic Assessment: Leukocyte Adhesion Deficiency current marketed and Leukocyte Adhesion Deficiency emerging therapies
• Leukocyte Adhesion Deficiency Market Dynamics: Leukocyte Adhesion Deficiency market drivers and Leukocyte Adhesion Deficiency market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Leukocyte Adhesion Deficiency Unmet Needs, KOL's views, Analyst's views, Leukocyte Adhesion Deficiency Market Access and Reimbursement

Discover more about therapies set to grab major Leukocyte Adhesion Deficiency market share @ Leukocyte Adhesion Deficiency market forecast
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Table of Contents
1. Leukocyte Adhesion Deficiency Market Report Introduction
2. Executive Summary for Leukocyte Adhesion Deficiency
3. SWOT analysis of Leukocyte Adhesion Deficiency
4. Leukocyte Adhesion Deficiency Patient Share (%) Overview at a Glance
5. Leukocyte Adhesion Deficiency Market Overview at a Glance
6. Leukocyte Adhesion Deficiency Disease Background and Overview
7. Leukocyte Adhesion Deficiency Epidemiology and Patient Population
8. Country-Specific Patient Population of Leukocyte Adhesion Deficiency
9. Leukocyte Adhesion Deficiency Current Treatment and Medical Practices
10. Leukocyte Adhesion Deficiency Unmet Needs
11. Leukocyte Adhesion Deficiency Emerging Therapies
12. Leukocyte Adhesion Deficiency Market Outlook
13. Country-Wise Leukocyte Adhesion Deficiency Market Analysis (2019-2032)
14. Leukocyte Adhesion Deficiency Market Access and Reimbursement of Therapies
15. Leukocyte Adhesion Deficiency Market Drivers
16. Leukocyte Adhesion Deficiency Market Barriers
17. Leukocyte Adhesion Deficiency Appendix
18. Leukocyte Adhesion Deficiency Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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