Press release
Cutaneous Lupus Erythematosus Clinical Trials, Emerging Therapies, Key Companies | A Drug Pipeline Analysis Report 2024 | Companies- Sanofi, Bristol Myers Squibb, Merck
Cutaneous Lupus Erythematosus Clinical Trials, Emerging Therapies, Key Companies
Key Takeaways from the Cutaneous Lupus Erythematosus Pipeline Report
Various Cutaneous Lupus Erythematosus pipeline therapies are in various stages of development, and their anticipated acceptance in the Cutaneous Lupus Erythematosus market would significantly increase market revenue.
Leading Cutaneous Lupus Erythematosus companies developing novel drug candidates to improve the Cutaneous Lupus Erythematosus treatment landscape include Sanofi, Bristol Myers Squibb, Merck, and others.
Promising Cutaneous Lupus Erythematosus pipeline therapies in various stages of development include Eclitasertib, Deucravacitinib, Enpatoran, Afimetoran, and others.
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Cutaneous Lupus Erythematosus Overview
The Cutaneous Lupus Erythematosus is an autoimmune skin disease that severely impairs quality of life.
Cutaneous manifestations may be present as a single separate skin disease entity or may occur in the setting of a severe multiorgan autoimmune disease with a wide variety of manifestations (such as systemic lupus erythematosus. Also, patients initially diagnosed with isolated CLE may later progress to SLE.
Similar to proposed etiologies for SLE, current theories discuss a multifactorial relationship leading to the development of cutaneous lupus, including genetic susceptibility, autoimmune induction, and immune system damage. Insights from genetic studies and environmental triggers in lupus pathogenesis implicate both innate and adaptive immune components.
The pathophysiology of cutaneous lupus erythematosus (CLE) encompasses the complex interactions between genetics, the environment, and cells and their products. Central to the pathogenesis is the loss of immune tolerance and up regulation of the interferon-α (IFN-α) signaling.
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Cutaneous Lupus Erythematosus Pipeline Analysis: Drug Profile
Eclitasertib: Sanofi
Eclitasertib formerly known as SAR443122 (Sanofi) is a small molecule of RIPK1 which is a critical signaling protein in the tumor necrosis factor receptor pathway and is a regulator of inflammation and cell death. Increased RIPK1 activity drives inflammation and cell necroptosis thoroughout the body and RIPK1 inhibition has been shown to have beneficial effects in preclinical models of many systemic inflammatory diseases. DNL758 is a potent and selective inhibitor of RIPK1 developed for the treatment of autoimmune diseases such as rheumatoid arthritis and peripheral inflammatory disease. Currently, it is in phase II clinical trial for CLE.
Discover more about the emerging Cutaneous Lupus Erythematosus drugs @ https://www.delveinsight.com/report-store/cutaneous-lupus-erythematosus-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Cutaneous Lupus Erythematosus Key Companies
Sanofi
Bristol Myers Squibb
Merck
And others
Cutaneous Lupus Erythematosus Pipeline Therapies and Key Companies
Eclitasertib
Deucravacitinib
Enpatoran
Afimetoran
And others
Cutaneous Lupus Erythematosus Pipeline Therapeutics Assessment
By development stage
By product type
By route of administration
By molecule type
By MOA type
Scope of the Cutaneous Lupus Erythematosus Pipeline Report
Coverage: Global
Key Cutaneous Lupus Erythematosus Companies: Eclitasertib, Deucravacitinib,Enpatoran, Afimetoran, and others
Key Cutaneous Lupus Erythematosus Pipeline Therapies: Eclitasertib, Deucravacitinib, Enpatoran, Afimetoran, and others
Find out more about the Cutaneous Lupus Erythematosus treatment options in development @ https://www.delveinsight.com/report-store/cutaneous-lupus-erythematosus-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Table of Contents
1. Introduction
2. Executive Summary
3. Overview
4. Pipeline Therapeutics
5. Late-Stage Products (Phase III)
6. Mid-Stage Products (Phase II)
7. Early Stage Products (Phase I/II)
8. Preclinical Stage Products
9. Discovery Stage Products
10. Therapeutic Assessment
11. Inactive Products
12. Collaborations Assessment- Licensing / Partnering / Funding
13. Unmet Needs
14. Market Drivers and Barriers
15. Appendix
16. About DelveInsight
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Contact Us:
Kritika Rehani
info@delveinsight.com
+14699457679
www.delveinsight.com
About DelveInsight:
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences.
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