Generalized Myasthenia Gravis Market Forecasted to Surge in Coming Years, 2023-2032 Analysis by DelveInsight | Viela Bio, UCB Pharma, Ra Pharmaceuticals, Argenx, Alexion Pharmaceuticals, Takeda, Argenx-Halozyme Therapeutics, Horizon Therapeutics, Hoffmann

DelveInsight's "Generalized Myasthenia Gravis Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the Generalized Myasthenia Gravis, historical and forecasted epidemiology as well as the Generalized Myasthenia Gravis market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

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Some of the key facts of the Generalized Myasthenia Gravis Market Report:
• The Generalized Myasthenia Gravis market size was valued approximately USD 2,700 million in 2021 and is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In Febuary 2024, Johnson & Johnson (J&J) unveiled favorable top-line findings for nipocalimab across two rare disease categories: generalized myasthenia gravis (gMG) and Sjogren's disease. These achievements follow positive outcomes observed in two other autoantibody-related conditions, namely, haemolytic disease of the foetus and newborn (HDFN) and rheumatoid arthritis (RA). The Phase III VIVACITY trial (NCT03772587) of nipocalimab in adult gMG patients achieved its primary objective, demonstrating a statistically significant decrease in daily activity scores (measured by the myasthenia gravis activities of daily living scale - MG-ADL) from baseline over a period of 22 to 24 weeks, relative to placebo.
• In January 2023, UCB, a global biopharmaceutical firm, announced today that the US Food and Drug Administration (FDA) has accepted its submission for the review of a Biologic License Application (BLA) concerning rozanolixizumab, an investigational treatment. Additionally, the FDA has granted Priority Review status to the application. Rozanolixizumab, a monoclonal antibody administered subcutaneously (SC), targets the neonatal Fc receptor (FcRn) and is intended for treating adults diagnosed with generalized myasthenia gravis (gMG) who test positive for anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuSK) antibodies.
• In 2021, the market size for Generalized Myasthenia Gravis (gMG) across the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan was estimated to be around USD 2,700 million.
• According to Suresh et al. (2021), there are 20 cases of myasthenia gravis for every 100,000 people in the United States. It shows that those under 40 have a higher female predominance, while people over 50 have a higher male predominance
• The prevalence of MG varies from 1.5 to 17.9, or 2.19 to 36.71 cases/100.000 population, depending on the region. This suggests that there are roughly 60.000 sufferers in the US and 56,000-123,000 in Europe
• According to a Green et al. (2020) study, 5.6% of the North American sample had non-family myasthenia gravis. While the majority of instances of myasthenia gravis are still not familial, a prevalence of 5.6% is several hundred times higher than the overall prevalence of 1 in 5-10 000 cases of the condition
• Key Generalized Myasthenia Gravis Companies: Viela Bio, UCB Pharma, Ra Pharmaceuticals, Argenx, Alexion Pharmaceuticals, Takeda, Argenx-Halozyme Therapeutics, Horizon Therapeutics, Hoffmann-La Roche, Janssen Research & Development, LLC, Immunovant Sciences GmbH, Sanofi, Cartesian Therapeutics, Takeda, DAS Therapeutics, Inc., and others
• Key Generalized Myasthenia Gravis Therapies: Inebilizumab, Rozanolixizumab, Zilucoplan, Efgartigimod, Eculizumab, TAK-079, Subcutaneous Efgartigimod, Uplizna (Inebilizumab), Enspryng (Satralizumab), Nipocalimab, Batoclimab, Tolebrutinib, Descartes-08, Mezagitamab (TAK-079), DAS-001, and others
• The Generalized Myasthenia Gravis epidemiology based on gender analyzed that prevalence of Generalized Myasthenia Gravis is higher in females than males
• The Generalized Myasthenia Gravis market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Generalized Myasthenia Gravis pipeline products will significantly revolutionize the Generalized Myasthenia Gravis market dynamics.

Generalized Myasthenia Gravis Overview
Generalized Myasthenia Gravis (gMG) is a chronic autoimmune neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. It occurs when the body's immune system produces antibodies that mistakenly attack and disrupt the communication between nerves and muscles.

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Generalized Myasthenia Gravis Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Generalized Myasthenia Gravis Epidemiology Segmentation:
The Generalized Myasthenia Gravis market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Generalized Myasthenia Gravis
• Prevalent Cases of Generalized Myasthenia Gravis by severity
• Gender-specific Prevalence of Generalized Myasthenia Gravis
• Diagnosed Cases of Episodic and Chronic Generalized Myasthenia Gravis

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Generalized Myasthenia Gravis Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Generalized Myasthenia Gravis market or expected to get launched during the study period. The analysis covers Generalized Myasthenia Gravis market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Generalized Myasthenia Gravis Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Generalized Myasthenia Gravis Therapies and Key Companies
• Inebilizumab: Viela Bio
• Rozanolixizumab: UCB Pharma
• Zilucoplan: Ra Pharmaceuticals
• Efgartigimod: Argenx
• Eculizumab: Alexion Pharmaceuticals
• TAK-079: Takeda
• Subcutaneous Efgartigimod: Argenx-Halozyme Therapeutics
• Uplizna (Inebilizumab): Horizon Therapeutics
• Enspryng (Satralizumab): Hoffmann-La Roche
• Nipocalimab: Janssen Research & Development, LLC
• Batoclimab: Immunovant Sciences GmbH
• Tolebrutinib: Sanofi
• Descartes-08: Cartesian Therapeutics
• Mezagitamab (TAK-079): Takeda
• DAS-001: DAS Therapeutics, Inc.

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Generalized Myasthenia Gravis Market Strengths
• Growing research and development is increasing the demand for better diagnosis and treatment options for MG.
• Approval of targeted therapies such as Soliris, Vygart, and Ultomiris will fuel the market growth.

Generalized Myasthenia Gravis Market Opportunities
• Approval of new therapies will provide better treatment options
• Various big Pharma key players are currently active in the development of a novel drug for the treatment of MG.

Scope of the Generalized Myasthenia Gravis Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Generalized Myasthenia Gravis Companies: Viela Bio, UCB Pharma, Ra Pharmaceuticals, Argenx, Alexion Pharmaceuticals, Takeda, Argenx-Halozyme Therapeutics, Horizon Therapeutics, Hoffmann-La Roche, Janssen Research & Development, LLC, Immunovant Sciences GmbH, Sanofi, Cartesian Therapeutics, Takeda, DAS Therapeutics, Inc., and others
• Key Generalized Myasthenia Gravis Therapies: Inebilizumab, Rozanolixizumab, Zilucoplan, Efgartigimod, Eculizumab, TAK-079, Subcutaneous Efgartigimod, Uplizna (Inebilizumab), Enspryng (Satralizumab), Nipocalimab, Batoclimab, Tolebrutinib, Descartes-08, Mezagitamab (TAK-079), DAS-001, and others
• Generalized Myasthenia Gravis Therapeutic Assessment: Generalized Myasthenia Gravis current marketed and Generalized Myasthenia Gravis emerging therapies
• Generalized Myasthenia Gravis Market Dynamics: Generalized Myasthenia Gravis market drivers and Generalized Myasthenia Gravis market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Generalized Myasthenia Gravis Unmet Needs, KOL's views, Analyst's views, Generalized Myasthenia Gravis Market Access and Reimbursement

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Table of Contents
1. Generalized Myasthenia Gravis Market Report Introduction
2. Executive Summary for Generalized Myasthenia Gravis
3. SWOT analysis of Generalized Myasthenia Gravis
4. Generalized Myasthenia Gravis Patient Share (%) Overview at a Glance
5. Generalized Myasthenia Gravis Market Overview at a Glance
6. Generalized Myasthenia Gravis Disease Background and Overview
7. Generalized Myasthenia Gravis Epidemiology and Patient Population
8. Country-Specific Patient Population of Generalized Myasthenia Gravis
9. Generalized Myasthenia Gravis Current Treatment and Medical Practices
10. Generalized Myasthenia Gravis Unmet Needs
11. Generalized Myasthenia Gravis Emerging Therapies
12. Generalized Myasthenia Gravis Market Outlook
13. Country-Wise Generalized Myasthenia Gravis Market Analysis (2019-2032)
14. Generalized Myasthenia Gravis Market Access and Reimbursement of Therapies
15. Generalized Myasthenia Gravis Market Drivers
16. Generalized Myasthenia Gravis Market Barriers
17. Generalized Myasthenia Gravis Appendix
18. Generalized Myasthenia Gravis Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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