Press release
Pancreatic Cancer Market Outlook Report 2032 | AstraZeneca, Merck Sharp & Dohme LLC, Bayer, Roche, Celgene, Bristol Myers Squibb, BioLineRx, Alligator Bioscience, Bellicum Pharmaceuticals, OSE Immunotherapeutics, Actuate Therapeutics, FibroGen, NeoImmuneT
DelveInsight's "Pancreatic Cancer Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of Pancreatic Cancer , historical and forecasted epidemiology as well as the Pancreatic Cancer market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.The Pancreatic Cancer market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Pancreatic Cancer market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Pancreatic Cancer treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Pancreatic Cancer market.
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Pancreatic Cancer Market Report Key Facts:
The United States accounts for the largest market size (around 50%) of pancreatic cancer, in comparison to EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.
Among the approved therapies, LYNPARZA (olaparib) is expected to garner the highest market share in the United States.
For pancreatic cancer patients showing BRCA mutations, LYNPARZA (olaparib) was approved by the US FDA in 2019. VITRAKVI (larotrectinib) and ROZLYTREK (entrectinib) are approved for solid tumor patients having NTRK gene expression. Other than these, KEYTRUDA (pembrolizumab) is approved for solid tumor patients having microsatellite instability-high expression.
In January 2024, Alligator Bioscience announced positive top-line results from the OPTIMIZE-1 Phase II study of the company's lead asset mitazalimab in first line metastatic pancreatic cancer.
The study achieved its primary endpoint demonstrating a confirmed objective response rate (ORR) of 40.4%, an unconfirmed ORR of 50.9% and a disease control rate (DCR) of 79% in 57 evaluable patients, as per the response evaluation criteria in solid tumors.
The development pipeline for pancreatic cancer is robust, with significant involvement from key players like Alligator Bioscience, Actuate Therapeutics, and other companies advancing into mid-stage clinical trials.
Among the 7MM, the United States had the highest incident cases of pancreatic cancer in 2023, representing approximately 35% of the total incident cases, while Japan had the second highest number of cases with nearly 25% of the total cases.
Pancreatic Cancer Overview
Pancreatic cancer is a malignant tumor of the pancreas, an organ located behind the stomach that plays a crucial role in digestion and blood sugar regulation. It is one of the most aggressive forms of cancer, often diagnosed at an advanced stage due to its subtle early symptoms. Here's an overview of pancreatic cancer, including its causes, signs and symptoms, diagnosis, and treatment options:
Pancreatic Cancer Causes:
The exact cause of pancreatic cancer is not fully understood, but several risk factors have been identified:
1. Genetic Factors: A family history of pancreatic cancer or certain genetic syndromes can increase risk.
2. Smoking: Tobacco use is a significant risk factor.
3. Age: Most cases occur in people over 60.
4. Chronic Pancreatitis: Long-term inflammation of the pancreas is associated with an increased risk.
5. Diabetes: Particularly new-onset diabetes in older adults.
6. Obesity: Excess body weight is a known risk factor.
7. Diet: A diet high in red and processed meats and low in fruits and vegetables may contribute to risk.
Pancreatic Cancer Signs and Symptoms:
Pancreatic cancer often does not cause symptoms in its early stages. When symptoms do appear, they can include:
1. Jaundice: Yellowing of the skin and eyes due to bile duct obstruction.
2. Weight Loss: Unexplained loss of weight.
3. Abdominal Pain: Often radiating to the back, which can be persistent or severe.
4. Loss of Appetite: Reduced desire to eat.
5. Nausea and Vomiting: Due to blockage of the digestive tract.
6. New-onset Diabetes: Sudden development of diabetes or difficulty controlling existing diabetes.
7. Fatigue: Persistent tiredness.
8. Dark Urine and Pale Stools: Due to bile duct obstruction.
Pancreatic Cancer Diagnosis:
Diagnosing pancreatic cancer involves a combination of imaging tests, blood tests, and biopsies:
1. Imaging Tests:
- CT Scan: Detailed cross-sectional images of the body to identify tumors.
- MRI: Detailed images of the pancreas and surrounding tissues.
- Endoscopic Ultrasound (EUS): Uses an endoscope with an ultrasound probe to get detailed images and guide needle biopsies.
- PET Scan: Detects cancerous cells by their increased uptake of glucose.
2. Blood Tests:
- Tumor Markers: CA 19-9 is a marker that may be elevated in pancreatic cancer.
- Liver Function Tests: To assess for jaundice and bile duct obstruction.
3. Biopsy:
- Fine-Needle Aspiration (FNA): Obtaining a tissue sample using a needle guided by imaging techniques.
- Surgical Biopsy: In some cases, a surgical procedure may be needed to obtain a tissue sample.
Pancreatic Cancer Treatment Options:
Treatment for pancreatic cancer depends on the stage of the disease, location of the tumor, and overall health of the patient. Options include:
1. Surgery:
- Whipple Procedure (Pancreaticoduodenectomy): Removal of the head of the pancreas, part of the small intestine, bile duct, and sometimes part of the stomach.
- Distal Pancreatectomy: Removal of the body and tail of the pancreas.
- Total Pancreatectomy: Removal of the entire pancreas, sometimes necessary for widespread disease.
2. Radiation Therapy:
- External Beam Radiation: High-energy beams are directed at the tumor to kill cancer cells.
- Stereotactic Body Radiation Therapy (SBRT): Delivers high doses of radiation to the tumor with precision.
3. Chemotherapy:
- Systemic Chemotherapy: Drugs like gemcitabine or FOLFIRINOX are used to kill cancer cells throughout the body.
- Neoadjuvant Chemotherapy: Given before surgery to shrink the tumor.
- Adjuvant Chemotherapy: Given after surgery to eliminate remaining cancer cells.
4. Targeted Therapy:
- Erlotinib: A drug that targets specific pathways in cancer cells, used in combination with chemotherapy for certain types of pancreatic cancer.
5. Immunotherapy:
- Checkpoint Inhibitors: Drugs that help the immune system recognize and attack cancer cells. This is an emerging area of treatment.
6. Palliative Care:
- Pain Management: Medications and procedures to control pain.
- Nutritional Support: Managing dietary needs and supplements.
- Biliary Stenting: To relieve jaundice by keeping bile ducts open.
Pancreatic Cancer Prognosis:
The prognosis for pancreatic cancer is generally poor, especially if diagnosed at a late stage. Early detection and advances in treatment have improved outcomes for some patients. Factors affecting prognosis include the stage at diagnosis, tumor size, lymph node involvement, and the patient's overall health and response to treatment.
Pancreatic Cancer Conclusion:
Pancreatic cancer is a serious and aggressive disease with complex causes and subtle early symptoms. Early diagnosis is challenging but crucial for improving outcomes. Treatment options are varied and tailored to the individual, including surgery, chemotherapy, radiation, and supportive care to manage symptoms and improve quality of life. Regular follow-ups and a multidisciplinary approach are essential for managing pancreatic cancer effectively.
Learn more about Pancreatic Cancer , treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ https://www.delveinsight.com/report-store/pancreatic-cancer-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Pancreatic Cancer Market
The Pancreatic Cancer market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Pancreatic Cancer market trends by analyzing the impact of current Pancreatic Cancer therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.
This segment gives a thorough detail of the Pancreatic Cancer market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Pancreatic Cancer market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the Pancreatic Cancer market in 7MM is expected to witness a major change in the study period 2019-2032.
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Pancreatic Cancer Epidemiology
The Pancreatic Cancer epidemiology section provides insights into the historical and current Pancreatic Cancer patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Pancreatic Cancer market report also provides the diagnosed patient pool, trends, and assumptions.
Explore more about Pancreatic Cancer Epidemiology at: https://www.delveinsight.com/report-store/pancreatic-cancer-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Pancreatic Cancer Drugs Uptake
This section focuses on the uptake rate of the potential Pancreatic Cancer drugs recently launched in the Pancreatic Cancer market or expected to be launched in 2019-2032. The analysis covers the Pancreatic Cancer market uptake by drugs, patient uptake by therapies, and sales of each drug.
Pancreatic Cancer Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Pancreatic Cancer market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Pancreatic Cancer Pipeline Development Activities
Pancreatic cancer is cancer that forms in the cells of the pancreas. Pancreatic cancer begins in the tissues of your pancreas - an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produces hormones that help manage your blood sugar.
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Pancreatic Cancer Therapeutics Assessment
Prominent players such as AstraZeneca, Merck Sharp & Dohme LLC, Bayer, Roche, Celgene, Bristol Myers Squibb, BioLineRx, Alligator Bioscience, Bellicum Pharmaceuticals, OSE Immunotherapeutics, Actuate Therapeutics, FibroGen, NeoImmuneTech, NOXXON Pharma, Silenseed Ltd., Amgen, NGM Biopharmaceuticals, Merus, Mirati Therapeutics, Rexahn Pharmaceuticals, Ocuphire Pharma, Processa Pharmaceuticals, ImmunityBio, Berg, Panbela Therapeutics, GlaxoSmithKline, Eleison Pharmaceuticals, Molecular Templates, Lokon Pharma AB, Cantargia AB, and others are working proactively in the Pancreatic Cancer Therapeutics market to develop novel therapies which will drive the Pancreatic Cancer treatment markets in the upcoming years.
Learn more about the emerging therapies & key companies at: https://www.delveinsight.com/report-store/pancreatic-cancer-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Pancreatic Cancer Report Key Insights
1. Pancreatic Cancer Patient Population
2. Pancreatic Cancer Market Size and Trends
3. Key Cross Competition in the Pancreatic Cancer Market
4. Pancreatic Cancer Market Dynamics (Key Drivers and Barriers)
5. Pancreatic Cancer Market Opportunities
6. Pancreatic Cancer Therapeutic Approaches
7. Pancreatic Cancer Pipeline Analysis
8. Pancreatic Cancer Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Pancreatic Cancer Market
Table of Contents
1. Key Insights
2. Executive Summary
3. Pancreatic Cancer Competitive Intelligence Analysis
4. Pancreatic Cancer Market Overview at a Glance
5. Pancreatic Cancer Disease Background and Overview
6. Pancreatic Cancer Patient Journey
7. Pancreatic Cancer Epidemiology and Patient Population
8. Pancreatic Cancer Treatment Algorithm, Current Treatment, and Medical Practices
9. Pancreatic Cancer Unmet Needs
10. Key Endpoints of Pancreatic Cancer Treatment
11. Pancreatic Cancer Marketed Products
12. Pancreatic Cancer Emerging Therapies
13. Pancreatic Cancer Seven Major Market Analysis
14. Attribute Analysis
15. Pancreatic Cancer Market Outlook (7 major markets)
16. Pancreatic Cancer Access and Reimbursement Overview
17. KOL Views on the Pancreatic Cancer Market
18. Pancreatic Cancer Market Drivers
19. Pancreatic Cancer Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
Get the Detailed TOC of the Pancreatic Cancer Market report here: https://www.delveinsight.com/report-store/pancreatic-cancer-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Contact Us:
Kritika Rehani
info@delveinsight.com
+14699457679
www.delveinsight.com
About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.
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