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Cartilage Degeneration Market - Emerging Trends and New Technologies Research 2016 - 2024

08-01-2016 11:44 AM CET | Health & Medicine

Press release from: TMR - MD

Cartilage is the tough, complex but flexible living tissue that covers the bony surface of joints. Articular cartilage, fibro cartilage and elastic cartilage are the three different types of cartilage present in the body. Articular cartilage is the one which covers joint surfaces, elastic cartilage is found in the outer ear and fibro cartilage is present in the vertebral disc and knee meniscus. All these three cartilages in the body are distinguished by elasticity, structure, and strength. It is responsible for providing shock absorption, and thus enables the joints to bear the weight associated with the daily activities as well as in various kinds of sports.

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The most common type of cartilage damage is that of articular cartilage, and may be caused due to injury or degeneration. Articular cartilage cells may heal depending on the extent of degeneration, and location of injury, however only in cases where an injury penetrates into the bone beneath the cartilage. Self healing capacity of the cartilage reduces since the cartilage has no direct blood supply, so little or no capacity to repair itself.

Cartilage is also responsible for providing shape and support to other parts of the body, such as nose, ears, and windpipe. Cartilage also provides protection to the bones by preventing them from friction against each other. Pain and restricted movement is observed in cases of injured, inflamed or damaged cartilage including joint deformity in some cases. There are several causes for cartilage problems which include genetic, trauma (injuries), nutritional, mal alignment and meniscus tear. According to a medical center in the U.S., more than 12 million people visit doctors due to knee pain each year, 50 % of them are diagnosed with cartilage damage.

Osteoarthritis is a leading cause of cartilage damage. Osteoarthritis, which is also known as degenerative joint disease is characterized by a loss of cartilage, the body’s attempt to repair the cartilage and, ultimately the destruction of the bone underneath the articular cartilage. Since the cartilage tissue does not contain blood vessels or nerves, treating this degeneration pose a challenge and have a limited ability to re-grow. Various treatment options for cartilage degeneration, such as, arthroscopy, drug therapy and joint replacement, have yielded mixed results of regenerating the damaged cartilage.

Medical researchers are also conducting various clinical studies in the U.S. of innovative stem cell therapy for repairing knee cartilage degenerated due to causes such as trauma, aging, or even arthritis. Cartistem is one such example by Rush University Medical Center which is developed from mesenchymal stem cells derived from allogenic umbilical cord blood. This Cartistem is administered surgically into the area of cartilage damage following an arthroscopic surgery. Studies and research on exploring various biological solutions to treat cartilage degeneration is currently one of the fastest growing area of research and development.

The global cartilage degeneration market can be segmented based on therapy type and pipeline assessment on the basis of target site, molecule type, mechanism of action and route of administration. Therapy type can be classified as monotherapy or combined therapeutics. Various drug molecules in pipeline for cartilage degeneration include sprifermin, chondrogen, and MSB-CAR-001 amongst various others. The alternative for the drug treatment includes minimal invasive procedures such as arthroscopy. The other regeneration procedures include autologus chonrocyte transplantation, cell based cartilage resurfacing, meniscus transplant, micro fracture, osteochondral allograft, and mosaicplasty.

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Calzada Limited, Merck KGaA, Mesoblast Limited, Sanofi and Thrasos, Inc., are some of the key players contributing to the global cartilage degeneration market.

The report offers a comprehensive evaluation of the market. It does so via in-depth insights, understanding market evolution by tracking historical developments, and analyzing the present scenario and future projections based on optimistic and likely scenarios. Each research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology developments, types, applications, and the competitive landscape.

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Transparency Market Research (TMR) is a global market intelligence company providing business information reports and services. The company’s exclusive blend of quantitative forecasting and trend analysis provides forward-looking insight for thousands of decision makers. TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources and various tools and techniques to gather and analyze information.

TMR’s data repository is continuously updated and revised by a team of research experts so that it always reflects the latest trends and information. With extensive research and analysis capabilities, Transparency Market Research employs rigorous primary and secondary research techniques to develop distinctive data sets and research material for business reports.

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