Cell and Gene Therapy Bio-Manufacturing Market Exclusive Report on Current Trends and Future Insights
InsightAce Analytic announces the release of a market assessment report on the "Global Cell and Gene Therapy Bio-manufacturing Market Size, Share & Trends Analysis Report By Product Type (Consumables, Equipment, And Software Solutions), Usage (Commercial-Stage Manufacturing And Research-Stage Manufacturing), Application (Upstream Processing, Harvesting, And Downstream Processing), And End-User (Life Science Companies, Contract Research Organizations (Cros), Contract Manufacturing Organizations (CMOs), And Cell Banks)- Market Outlook And Industry Analysis 2031"The global cell and gene therapy bio-manufacturing market is estimated to reach over USD 29.34 billion by 2031, exhibiting a CAGR of 11.25% during the forecast period.
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The global cell and gene therapy bio-manufacturing market is expected to experience growth due to the increasing number of authorized medicines and the expanding infrastructure requirements. Expanding cell and gene therapy target indications also generates a need for large-scale bio-manufacturing. Additional factors propelling the expansion of cell and gene therapy manufacturing include substantial investments by government entities and prominent market participants. Gene therapy companies have received approximately USD 2.3 billion in funding over the past decade. This exorbitant quantity suggests that substantial pharmaceutical and biotechnology corporations invest in the most prominent gene therapy businesses. Large service providers perceive Gene and cell therapy as an active investment sector, including CDMOs/CMOs and in-house manufacturers.
Furthermore, pharmaceutical and biotechnology organizations are making substantial investments in the research and development of cell and gene therapies. The United States Food and Drug Administration (USFDA) has reported a significant increase in the number of cell and gene therapy items currently in the early stages of development. As a result of the aforementioned factors, the market is anticipated to experience a robust rate of growth during the forecast period.
List of Prominent Players in the Cell and Gene Therapy Bio-manufacturing Market:
• Lonza Group Ltd
• Merck KGaA
• Miltenyi Biotec B.V. & Co. KG
• PIERRE GUERIN
• Sartorius AG (Sartorius Stedim Biotech S.A.)
• Thermo Fisher Scientific Inc.
• WuXi AppTec
• Becton, Dickinson and Company
• Endress+Hauser Group Services AG (Analytik Jena GmbH)
• Danaher Corporation
• Bio-Rad Laboratories, Inc.
• Bio-Techne Corporation
• General Electric Company (G.E. Healthcare)
• Getinge AB
• Infors AG
Market Dynamics:
Drivers-
The market is expanding due to the increasing prevalence of cancer and other target diseases, as well as the increased investment in research and development by pharmaceutical companies.
GLOBOCAN 2020 has been updated by the International Agency for Research on Cancer (IARC) with new cancer burden estimates, which suggest that the number of cases has increased to 19.3 million. The market will experience growth as the number of instances increases, which will also increase the reliance on gene therapy. In the same vein, the global prevalence of osteoporosis was reported to be 18.3% in a paper published in October 2021 by the Journal of Orthopedic Surgery and Research, titled "The Worldwide Prevalence of Osteoporosis in the World: A Comprehensive Systematic Analysis and Meta-analysis." Treatment with stem cells for osteoporosis has the potential to reduce the likelihood of fractures. The demand for cell and gene therapy manufacturing services will increase in tandem with the increase in the prevalence of orthopedic ailments.
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Challenges:
The excessive cost of all medicines is one of the most significant issues, as it is expected to impede market expansion and has financial repercussions for patients, providers, and prayers. For example, the US FDA approved chimeric antigen receptor T-cell therapy in May 2022 for the treatment of pediatric and young adult patients with refractory or relapsed B-cell precursor acute lymphoblastic leukemia. A single infusion costs approximately USD 475,000. Consequently, the market has experienced limited growth because of the limited adoption of these therapies.
Regional Trends:
The North American Cell and Gene Therapy Bio-manufacturing Market is anticipated to experience a significant increase in revenue and to expand at a higher CAGR in the near future as a result of the growing geriatric population and the increasing prevalence and incidence of infectious diseases in the region. The United States is the most affected country in the world, despite the widespread use of gene treatments in diagnostic, therapeutic, drug development, and other research for oncology and other clinical maladies. Consequently, the demand for the same will be significantly higher in the North American region, where the patient population is expanding at a quicker pace than in other countries.
Recent Developments:
• In January 2022, Antion Biosciences Inc. and Allogen Therapeutics Inc. have entered into an exclusive collaboration and global license agreement for Antion's miRNA technology (miCAR). The purpose of this agreement is to facilitate the development of next-generation allogeneic CAR T products by advancing multiplex gene silencing.
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Segmentation of Cell and Gene Therapy Bio-manufacturing Market-
By Usage-
• Commercial Stage Manufacturing
• Research Stage Manufacturing
By Product Type-
• Consumables
• Culture Supplements
• Media
• Serum
• Macronutrients
• Single-Use Liquids
• Cell Culture Reagents
• Cell Quantification Kits
• Equipment
• Bioreactors/Fermenters
• Continuous Bioreactors
• Single-Use Bioreactors
• Mixing Systems
• Cell Counters
• Cell Sorters
• Centrifuges
• Incubators
• Biosafety Cabinets
• Freezers
• PCR Systems
• Transfection Systems
• Storage Tanks
• Others
• Software Solutions
By Application-
• Upstream Processing
• Formulation and Hydration
• Cell Culture Processing
• Harvesting
• Downstream Processing
• Separation and Filtration
• Fill and Finish Operations
By End-User-
• Life Science Companies
• Equipment
• Consumables
• Software Solutions
• Contract Research Organizations (CROs)
• Equipment
• Consumables
• Software Solutions
• Contract Manufacturing Organizations (CMOs)
• Equipment
• Consumables
• Software Solutions
• Cell Banks
• Equipment
• Consumables
• Software Solutions
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
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