Advanced Renal Cell Carcinoma FDA Approvals, Clinical Trials, Emerging Drugs, and Pipeline Report 2024 (Updated)

DelveInsight's, "Advanced Renal Cell Carcinoma Pipeline Insight 2024" report provides comprehensive insights about 50+ companies and 60+ pipeline drugs in the Advanced Renal Cell Carcinoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Advanced Renal Cell Carcinoma Pipeline Report
• DelveInsight's Advanced Renal Cell Carcinoma pipeline report depicts a robust space with 50+ active players working to develop 60+ pipeline therapies for Advanced Renal Cell Carcinoma treatment.
• The leading companies working in the Advanced Renal Cell Carcinoma market include Merck Sharp & Dohme, Chia Tai Tianqing Pharmaceutical, Hoffmann-La Roche, CoImmune, Infinity Pharmaceuticals, NiKang Therapeutics, Molecure S.A., Daiichi Sankyo, Janux Therapeutics, MedImmune, Eli Lilly and Company, Jiangsu HengRui Medicine Co., Ltd., Allogene Therapeutics, Chongqing Precision Biotech Co., Ltd, Pfizer, Exelixis, BeiGene, Xencor, and others.
• Promising Advanced Renal Cell Carcinoma Pipeline Therapies in the various stages of development include ABT-869, MEDI5752, Axitinib, Lenvatinib, CMN-001, Cabozantinib, Sorafenib, Tivozanib (AV-951), and others.
• April 2024: Ipsen- A Prospective Observational International Study of Cabozantinib Tablets in Combination With Nivolumab as First-line Treatment of Advanced Renal Cell Carcinoma in Adults. The purpose of this study is to collect data to describe the safety and effectiveness of cabozantinib and nivolumab in combination as a first-line treatment in adults with aRCC with clear cell-component, according to real-world clinical practice. The decision to prescribe cabozantinib and nivolumab in combination will be made prior to, and independently from, the decision to enrol the participant in study.
• April 2024:- Bristol-Myers Squibb- Real-World Treatment Patterns and Outcomes of Advanced Renal Cell Carcinoma (aRCC) Patients Receiving Nivolumab+Ipilimumab or Pembrolizumab+Lenvatinib in U.S. Oncology Practice. This observational study aims to describe demographic, clinical characteristics, treatment patterns outcomes of participants with advanced Renal Cell Carcinoma (aRCC) receiving either Nivolumab + Ipilimumab, or Pembrolizumab + Lenvatinib combination therapy

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The Advanced Renal Cell Carcinoma pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage Advanced Renal Cell Carcinoma drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the Advanced Renal Cell Carcinoma clinical trial landscape.

Advanced Renal Cell Carcinoma Overview
According to the Centers for Disease Control and Prevention (CDC) Trusted Source, Renal Cell Carcinoma (RCC) is the most common type of kidney cancer. This type of cancer develops in the lining of very small tubes, or tubules, inside the kidney. These tubules help to remove waste products from the blood.

Find out more about Advanced Renal Cell Carcinoma Treatment Landscape @ Drugs for Advanced Renal Cell Carcinoma Treatment- https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Advanced Renal Cell Carcinoma Emerging Drugs Profile

• Belzutifan: Merck Sharp & Dohme
Belzutifan is an inhibitor of hypoxia-inducible factor 2 alpha (HIF-2a). Belzutifan binds to HIF-2a, and in conditions of hypoxia or impairment of VHL protein function, belzutifan inhibits the HIF-2a-HIF-1ß interaction, leading to reduced transcription and expression of HIF-2a target genes. Currently, the drug is being evaluated in the Phase III stage of its development for the treatment of advanced renal cell carcinoma.

• IPI-549: Infinity Pharmaceuticals
Eganelisib is a first-in-class, oral, once-daily, immuno-oncology development candidate that selectively inhibits phosphoinositide-3-kinase gamma (PI3K-gamma). Selective PI3K-gamma inhibition represents a unique and potentially transformative approach within immuno-oncology (I/O), and IPI-549 has the potential to be a first-in-class therapy. Preclinical research conducted by Infinity and academic collaborators demonstrates that IPI-549 works by reprogramming key immune suppressive cells (called M2 macrophages or myeloid derived suppressor cells (MDSCs)) within the tumor microenvironment from a pro-tumor function to an anti-tumor function, decreasing immune suppression and increasing immune activation, ultimately leading to the activation and proliferation of T cells that can attack cancer cells. Currently, the drug is being evaluated in the Phase II stage of its development for the treatment of advanced renal cell carcinoma.

• JANX008: Janux Therapeutics
JANX008 is an EGFR-TRACTr that is designed to overcome CRS and known on-target EGFR healthy tissue toxicities. Epidermal growth factor receptor (EGFR) is a clinically validated target highly expressed on many solid tumors that are being underserved by current therapies. JANX008 targets EGFR for the treatment of multiple solid cancers including, but not limited to, colorectal cancer (CRC), squamous cell carcinoma of the head and neck (SCCHN), non-small cell lung cancer (NSCLC), and renal cell carcinoma (RCC). Currently, the drug is being evaluated in the Phase I stage of its development for the treatment of advanced renal cell carcinoma.

Advanced Renal Cell Carcinoma Therapeutics Assessment
There are approx. 50+ key companies which are developing the therapies for Advanced Renal Cell Carcinoma. The Advanced Renal Cell Carcinoma companies which have their Advanced Renal Cell Carcinoma drug candidates in the most advanced stage, i.e. phase III include, Merck Sharp & Dohme.

DelveInsight's Advanced Renal Cell Carcinoma pipeline report covers around 60+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Advanced Renal Cell Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Intravenous
• Subcutaneous
• Parenteral
• Topical

Products have been categorized under various Molecule types such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Learn more about the emerging Advanced Renal Cell Carcinoma Pipeline Therapies @ Advanced Renal Cell Carcinoma Clinical Trials Assessment- https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Advanced Renal Cell Carcinoma Pipeline Report
• Coverage- Global
• Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Advanced Renal Cell Carcinoma Companies- Merck Sharp & Dohme, Chia Tai Tianqing Pharmaceutical, Hoffmann-La Roche, CoImmune, Infinity Pharmaceuticals, NiKang Therapeutics, Molecure S.A., Daiichi Sankyo, Janux Therapeutics, MedImmune, Eli Lilly and Company, Jiangsu HengRui Medicine Co., Ltd., Allogene Therapeutics, Chongqing Precision Biotech Co., Ltd, Pfizer, Exelixis, BeiGene, Xencor, and others.
• Advanced Renal Cell Carcinoma Pipeline Therapies- ABT-869, MEDI5752, Axitinib, Lenvatinib, CMN-001, Cabozantinib, Sorafenib, Tivozanib (AV-951), and others

Dive deep into rich insights for new drugs for Advanced Renal Cell Carcinoma Treatment, Visit @ Advanced Renal Cell Carcinoma Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Advanced Renal Cell Carcinoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Advanced Renal Cell Carcinoma- DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. Belzutifan: Merck Sharp & Dohme
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. IPI-549: Infinity Pharmaceuticals
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. JANX008: Janux Therapeutics
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug Name: Company Name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Advanced Renal Cell Carcinoma Key Companies
21. Advanced Renal Cell Carcinoma Key Products
22. Advanced Renal Cell Carcinoma- Unmet Needs
23. Advanced Renal Cell Carcinoma- Market Drivers and Barriers
24. Advanced Renal Cell Carcinoma- Future Perspectives and Conclusion
25. Advanced Renal Cell Carcinoma Analyst Views
26. Advanced Renal Cell Carcinoma Key Companies
27. Appendix

For further information on the Advanced Renal Cell Carcinoma Pipeline therapeutics, reach out to Advanced Renal Cell Carcinoma Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/advanced-renal-cell-carcinoma-rcc-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

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