Diabetic Retinopathy Clinical Trials Analysis 2024: FDA Approvals, Therapies, Mechanism of Action, Route of Administration and Companies by DelveInsight

(Albany, United States) As per DelveInsight's assessment, globally, Diabetic Retinopathy pipeline constitutes 50+ key companies continuously working towards developing 55+ Diabetic Retinopathy treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Diabetic Retinopathy Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Diabetic Retinopathy Market.
The Diabetic Retinopathy Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

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Some of the key takeaways from the Diabetic Retinopathy Pipeline Report:
• Diabetic Retinopathy Companies across the globe are diligently working toward developing novel Diabetic Retinopathy treatment therapies with a considerable amount of success over the years.
• Diabetic Retinopathy companies working in the treatment market are Kodiak Sciences, Novartis, Regenxbio Inc., OcuTerra Therapeutics, Ocular Therapeutix, Bayer, RemeGen, Roche, Ocuphire Pharma, Adverum Biotechnologies, Boehringer Ingelheim, Palatin Technologies, Valo Health, EyePoint Pharmaceuticals, Kubota Vision, MingSight Pharmaceuticals, Oxurion, Aerie Pharmaceuticals, AsclepiX Therapeutics, Ocugen, Ashvattha Therapeutics, Stealth BioTherapeutics, and others, are developing therapies for the Diabetic Retinopathy treatment
• In May 2023, Oculic Holding AG unveiled favorable initial outcomes from Stage 1 of the Phase III DIAMOND trial concerning OCS-01 eye drops in diabetic macular edema (DME). The trial's Stage 1 successfully confirmed the intended dosing regimen's efficacy for OCS-01 in treating diabetic macular edema, achieving substantial statistical significance as per the company's statement.
• In April 2023, Palatin Technologies announced the publication of a manuscript titled "Stimulating the Melanocortin System in Uveitis and Diabetes Preserves the Structure and Anti-Inflammatory Activity of the Retina" in The International Journal of Molecular Sciences. The manuscript, authored by Tat Fong Ng and Andrew W. Taylor from the Department of Ophthalmology at Boston University Chobanian and Avedisian School of Medicine in Massachusetts, summarizes findings on PL8331's effects in experimental autoimmune uveoretinitis (EAU) and diabetic retinopathy (DR) in mouse models of retinal disease. The study received funding support from Palatin, the National Institute of Health (NIH), and the Massachusetts Lions Eye Research Foundation.
• In February 2023, Ocugen revealed the submission of an Investigational New Drug application (IND) to the US Food and Drug Administration (FDA) for the commencement of a Phase 1 clinical trial evaluating OCU200. This fusion protein, showcasing a unique mechanism of action (MOA), aims to address diabetic macular edema (DME). The accomplishment of this regulatory milestone fulfills Ocugen's commitment to file the OCU200 IND within the initial quarter of 2023.
• In January 2023, Ocuphire Pharma disclosed the top-line findings of its ZETA-1 Phase II trial, assessing oral APX3330 for diabetic retinopathy (DR) treatment. The trial demonstrated promising safety and tolerability of oral APX3330, hinting at its potential as a non-invasive option for safeguarding vision in both eyes among patients with DR.
• In May 2022, EyePoint Pharmaceuticals disclosed the licensing agreement of EYP-1901 to Betta Pharmaceuticals for development and commercialization in China, Hong Kong, Macau, and Taiwan. While retaining all rights for EYP-1901 globally, EyePoint broadens its exclusive rights concerning the local delivery of vorolanib. This expansion encompasses the treatment of various ophthalmic diseases, encompassing diabetic macular edema (DME).

Diabetic Retinopathy Overview
Diabetic retinopathy is a diabetes-related eye condition that affects the retina, the light-sensitive tissue at the back of the eye. High blood sugar levels damage the blood vessels in the retina, leading to leakage, swelling, and the growth of abnormal new blood vessels. This can cause vision problems and, if left untreated, blindness.
There are two main stages of diabetic retinopathy: non-proliferative and proliferative. Non-proliferative diabetic retinopathy (NPDR) is the early stage where blood vessels weaken and develop microaneurysms, leading to fluid leakage into the retina. As the condition progresses to proliferative diabetic retinopathy (PDR), new, fragile blood vessels form, which can bleed into the vitreous humor, cause retinal detachment, and significantly impair vision.
Diabetic retinopathy symptoms may include blurred vision, dark spots, floaters, and difficulty seeing at night. However, in the early stages, there might be no symptoms, making regular eye examinations crucial for early detection and management.
Diabetic retinopathy treatment options include controlling blood sugar levels, laser surgery to seal or shrink leaking blood vessels, and injections of medications to reduce swelling and inhibit abnormal blood vessel growth. Early diagnosis and intervention are essential to prevent severe vision loss and maintain eye health in individuals with diabetes.

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Emerging Diabetic Retinopathy Drugs Under Different Phases of Clinical Development Include:
• PL8177: Palatin Technologies
• ABI-110: Avirmax Biopharma
• OTX-TKI: Ocular Therapeutix, Inc.
• MS-553: MingSight Pharmaceuticals, Inc
• OTT166: OcuTerra Therapeutics, Inc.
• RC28-E injection: RemeGen Co., Ltd.
• KSI-301: Kodiak Sciences Inc

Diabetic Retinopathy Route of Administration
Diabetic Retinopathy pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical

Diabetic Retinopathy Molecule Type
Diabetic Retinopathy Products have been categorized under various Molecule types, such as
• Recombinant fusion proteins
• Small molecule
• Monoclonal antibody
• Peptide
• Polymer
• Gene therapy

Diabetic Retinopathy Pipeline Therapeutics Assessment
• Diabetic Retinopathy Assessment by Product Type
• Diabetic Retinopathy By Stage and Product Type
• Diabetic Retinopathy Assessment by Route of Administration
• Diabetic Retinopathy By Stage and Route of Administration
• Diabetic Retinopathy Assessment by Molecule Type
• Diabetic Retinopathy by Stage and Molecule Type

DelveInsight's Diabetic Retinopathy Report covers around 55+ products under different phases of clinical development like
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Diabetic Retinopathy product details are provided in the report. Download the Diabetic Retinopathy pipeline report to learn more about the emerging Diabetic Retinopathy therapies
https://www.delveinsight.com/sample-request/diabetic-retinopathy-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Some of the key companies in the Diabetic Retinopathy Therapeutics Market include:
Key companies developing therapies for Diabetic Retinopathy are - Kodiak Sciences, Novartis, Regenxbio Inc., OcuTerra Therapeutics, Ocular Therapeutix, Bayer, RemeGen, Roche, Ocuphire Pharma, Adverum Biotechnologies, Boehringer Ingelheim, Palatin Technologies, Valo Health, EyePoint Pharmaceuticals, Kubota Vision, MingSight Pharmaceuticals, Oxurion, Aerie Pharmaceuticals, AsclepiX Therapeutics, Ocugen, Ashvattha Therapeutics, Stealth BioTherapeutics, and others.

Diabetic Retinopathy Pipeline Analysis:
The Diabetic Retinopathy pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Diabetic Retinopathy with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Diabetic Retinopathy Treatment.
• Diabetic Retinopathy key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Diabetic Retinopathy Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Diabetic Retinopathy market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

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Diabetic Retinopathy Pipeline Market Drivers
• High healthcare Expenditure, increase in patient awareness about diabetes, presence of well-established healthcare infrastructure and favorable reimbursement framework are some of the important factors that are fueling the Diabetic Retinopathy Market.

Diabetic Retinopathy Pipeline Market Barriers
• However, poor access to care, out-of-pocket expenses, insufficient patient knowledge or awareness of Diabetic Retinopathy and other factors are creating obstacles in the Diabetic Retinopathy Market growth.

Scope of Diabetic Retinopathy Pipeline Drug Insight
• Coverage: Global
• Key Diabetic Retinopathy Companies: , and others
• Key Diabetic Retinopathy Therapies: , and others
• Diabetic Retinopathy Therapeutic Assessment: Diabetic Retinopathy current marketed and Diabetic Retinopathy emerging therapies
• Diabetic Retinopathy Market Dynamics: Diabetic Retinopathy market drivers and Diabetic Retinopathy market barriers

Request for Sample PDF Report for Diabetic Retinopathy Pipeline Assessment and clinical trials
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Table of Contents
1. Diabetic Retinopathy Report Introduction
2. Diabetic Retinopathy Executive Summary
3. Diabetic Retinopathy Overview
4. Diabetic Retinopathy- Analytical Perspective In-depth Commercial Assessment
5. Diabetic Retinopathy Pipeline Therapeutics
6. Diabetic Retinopathy Late Stage Products (Phase II/III)
7. Diabetic Retinopathy Mid Stage Products (Phase II)
8. Diabetic Retinopathy Early Stage Products (Phase I)
9. Diabetic Retinopathy Preclinical Stage Products
10. Diabetic Retinopathy Therapeutics Assessment
11. Diabetic Retinopathy Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Diabetic Retinopathy Key Companies
14. Diabetic Retinopathy Key Products
15. Diabetic Retinopathy Unmet Needs
16 . Diabetic Retinopathy Market Drivers and Barriers
17. Diabetic Retinopathy Future Perspectives and Conclusion
18. Diabetic Retinopathy Analyst Views
19. Appendix
20. About DelveInsight

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