Irritable Bowel Syndrome Market Outlook Report 2032 | 4D Pharma, Cosmo Pharmaceuticals, RedHill Biopharma, Seed Health, NGM Biopharmaceuticals, and others

DelveInsight's "Irritable Bowel Syndrome Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of Irritable Bowel Syndrome, historical and forecasted epidemiology as well as the Irritable Bowel Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.


The Irritable Bowel Syndrome market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Irritable Bowel Syndrome market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Irritable Bowel Syndrome treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Irritable Bowel Syndrome market.

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Irritable Bowel Syndrome Overview

Irritable Bowel Syndrome is a common functional gastrointestinal disorder characterized by a group of symptoms that typically occur together, including abdominal pain and changes in bowel habits such as diarrhea, constipation, or alternating between both. IBS is a chronic condition that requires long-term management.
Irritable Bowel Syndrome Causes
The exact cause of IBS is not well understood, but several factors are believed to play a role:
Abnormal Gut Motility:
Irregular muscle contractions in the intestines can lead to food moving too quickly or too slowly through the digestive tract, causing diarrhea or constipation.
Gut-Brain Interaction:
Communication issues between the brain and the gut can lead to abnormal regulation of gastrointestinal function, contributing to IBS symptoms.
Increased Sensitivity:
People with IBS may have a heightened sensitivity to normal intestinal activities, leading to pain or discomfort.
Infections:
A history of severe gastroenteritis or bacterial overgrowth in the intestines can trigger IBS.
Changes in Gut Microbiota:
An imbalance in the gut microbiome may play a role in the development of IBS.
Stress and Mental Health:
Stress and psychological conditions such as anxiety and depression are associated with IBS and can exacerbate symptoms.
Genetics:
A family history of IBS suggests a genetic component, although no specific genes have been identified.
Irritable Bowel Syndrome Signs and Symptoms
IBS symptoms vary but commonly include:
Abdominal Pain or Cramping: Often relieved by passing stool or gas.
Bloating: A feeling of fullness or swelling in the abdomen.
Changes in Bowel Habits:
Diarrhea (IBS-D)
Constipation (IBS-C)
Alternating diarrhea and constipation (IBS-M, mixed)
Gas: Excessive flatulence.
Mucus in Stool: Presence of white mucus in the stool.
Urgency: A sudden need to defecate.
Incomplete Evacuation: Feeling of incomplete bowel movement.
Irritable Bowel Syndrome Diagnosis
Diagnosing IBS involves ruling out other conditions and may include:
Medical History and Symptom Assessment:
Detailed review of symptoms, their onset, duration, and relation to diet, stress, and other factors.
Rome Criteria:
Recurrent abdominal pain on average at least one day per week in the last three months, associated with two or more of the following:
Pain related to defecation.
Change in frequency of stool.
Change in form (appearance) of stool.
Physical Examination:
General examination to check for signs of other conditions.
Laboratory Tests:
Blood tests to rule out infections, inflammation, and other conditions.
Stool tests to check for infections, parasites, and blood.
Diagnostic Procedures:
Colonoscopy or Sigmoidoscopy: Visual examination of the colon to rule out other conditions such as inflammatory bowel disease (IBD) or colorectal cancer.
CT Scan or X-ray: Imaging studies to rule out structural abnormalities.
Irritable Bowel Syndrome Treatment Options
Treatment of IBS focuses on relieving symptoms and improving quality of life, often involving a combination of dietary changes, lifestyle modifications, medications, and psychological support:
Dietary Changes:
Low FODMAP Diet: Avoiding foods high in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.
Fiber Supplements: Soluble fiber may help with constipation; insoluble fiber might worsen symptoms in some people.
Avoiding Trigger Foods: Identifying and avoiding foods that exacerbate symptoms, such as caffeine, alcohol, fatty foods, and certain artificial sweeteners.
Medications:
Antispasmodics: To reduce abdominal cramping and pain (e.g., hyoscine, dicyclomine).
Laxatives: For constipation-predominant IBS (e.g., polyethylene glycol, lactulose).
Antidiarrheals: For diarrhea-predominant IBS (e.g., loperamide).
Antidepressants: Low doses of tricyclic antidepressants (TCAs) or selective serotonin reuptake inhibitors (SSRIs) to relieve pain and address associated anxiety or depression.
Gut-Acting Antibiotics: Rifaximin for reducing bacterial overgrowth.
Bile Acid Sequestrants: For diarrhea-predominant IBS.
Lifestyle Modifications:
Regular Exercise: Helps reduce stress and stimulate normal bowel function.
Adequate Hydration: Drinking plenty of fluids, especially water.
Stress Management: Techniques such as yoga, meditation, and counseling.
Psychological Therapies:
Cognitive Behavioral Therapy (CBT): Helps manage stress and alter negative thought patterns.
Gut-Directed Hypnotherapy: Can be effective in reducing symptoms.
Probiotics:
Certain strains of probiotics may help balance the gut microbiota and reduce symptoms.
Irritable Bowel Syndrome Follow-up and Monitoring
Regular follow-up with a healthcare provider is essential to monitor symptoms, adjust treatment plans, and manage any new or worsening symptoms. Patients are encouraged to keep a symptom diary to track triggers and responses to treatments.
By combining lifestyle modifications, dietary adjustments, and appropriate medical therapies, many individuals with IBS can achieve significant symptom relief and improve their quality of life.

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Irritable Bowel Syndrome Market

The Irritable Bowel Syndrome market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Irritable Bowel Syndrome market trends by analyzing the impact of current Irritable Bowel Syndrome therapies on the market and unmet needs, drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the Irritable Bowel Syndrome market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Irritable Bowel Syndrome market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to DelveInsight, the Irritable Bowel Syndrome market in 7MM is expected to witness a major change in the study period 2019-2032.

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Irritable Bowel Syndrome Epidemiology

The Irritable Bowel Syndrome epidemiology section provides insights into the historical and current Irritable Bowel Syndrome patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Irritable Bowel Syndrome market report also provides the diagnosed patient pool, trends, and assumptions.

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Irritable Bowel Syndrome Drugs Uptake

This section focuses on the uptake rate of the potential Irritable Bowel Syndrome drugs recently launched in the Irritable Bowel Syndrome market or expected to be launched in 2019-2032. The analysis covers the Irritable Bowel Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.

Irritable Bowel Syndrome Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Irritable Bowel Syndrome market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Irritable Bowel Syndrome Pipeline Development Activities

The Irritable Bowel Syndrome report provides insights into different therapeutic candidates in Phase II and Phase III stages. It also analyzes Irritable Bowel Syndrome key players involved in developing targeted therapeutics.

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Irritable Bowel Syndrome Therapeutics Assessment

Prominent players such as 4D Pharma, Cosmo Pharmaceuticals, RedHill Biopharma, Seed Health, NGM Biopharmaceuticals, and others are working proactively in the Irritable Bowel Syndrome Therapeutics market to develop novel therapies which will drive the Irritable Bowel Syndrome treatment markets in the upcoming years.

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Irritable Bowel Syndrome Report Key Insights

1. Irritable Bowel Syndrome Patient Population
2. Irritable Bowel Syndrome Market Size and Trends
3. Key Cross Competition in the Irritable Bowel Syndrome Market
4. Irritable Bowel Syndrome Market Dynamics (Key Drivers and Barriers)
5. Irritable Bowel Syndrome Market Opportunities
6. Irritable Bowel Syndrome Therapeutic Approaches
7. Irritable Bowel Syndrome Pipeline Analysis
8. Irritable Bowel Syndrome Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Irritable Bowel Syndrome Market

Table of Contents

1. Key Insights
2. Executive Summary
3. Irritable Bowel Syndrome Competitive Intelligence Analysis
4. Irritable Bowel Syndrome Market Overview at a Glance
5. Irritable Bowel Syndrome Disease Background and Overview
6. Irritable Bowel Syndrome Patient Journey
7. Irritable Bowel Syndrome Epidemiology and Patient Population
8. Irritable Bowel Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Irritable Bowel Syndrome Unmet Needs
10. Key Endpoints of Irritable Bowel Syndrome Treatment
11. Irritable Bowel Syndrome Marketed Products
12. Irritable Bowel Syndrome Emerging Therapies
13. Irritable Bowel Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Irritable Bowel Syndrome Market Outlook (7 major markets)
16. Irritable Bowel Syndrome Access and Reimbursement Overview
17. KOL Views on the Irritable Bowel Syndrome Market
18. Irritable Bowel Syndrome Market Drivers
19. Irritable Bowel Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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