Exosomes Pipeline, Clinical Trials, Emerging Drugs, FDA Approvals, and Companies 2024 (Updated)

DelveInsight's, "Exosomes Pipeline Insight 2024" report provides comprehensive insights about 66+ companies and 75+ pipeline drugs in the Exosomes pipeline landscape. It covers the Exosomes pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Exosomes pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Exosomes Pipeline Report
• DelveInsight's Exosomes pipeline report depicts a robust space with 60+ active players working to develop 75+ pipeline therapies for Exosomes treatment.
• The leading companies working in the Exosomes Market include Celularity, EVerZom, Direct Biologics, Regeneus, Capricor Therapeutics, Aegle Therapeutics, Organicell, Evecxia, ArunaBio, Evox, Coya Therapeutics, ILIAS Biologics, and EXO Biologics and others.
• Promising Exosomes Pipeline Therapies in the various stages of development include Exosome ointment, EV-Pure™, Zofin, Olmutinib, and others.
• May 2024:- Services Hospital Lahore- Efficacy and Safety of Exosomes Versus Platelet Rich Plasma in Patients of Androgenetic Alopecia. Androgenetic alopecia is a common condition affects both genders. Patients of androgenetic alopecia following inclusion criteria will be enrolled after ethical approval and informed consent. Pre-treatment assessment will be done by Physian Global assessment, Patient global assessment and hair density by trichoscopy of areas under treatment. Patients will be categorized in 2 groups.

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In the Exosomes pipeline report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Exosomes collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Exosomes Overview
An exosome is a type of extracellular vesicle (EV), a family of nanometer-scale, biomolecule-filled, lipid-wrapped packages released by most cells. Exosomes are released from cells upon fusion of an intermediate endocytic compartment, the multivesicular body (MVB), with the plasma membrane. This liberates intraluminal vesicles (ILVs) into the extracellular milieu and the vesicles thereby released are what we know as exosomes.

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Exosomes Emerging Drugs Profile

• CAP-1002: Capricor
CAP-1002 consists of allogeneic cardiosphere-derived cells (CDCs), a population of stromal cells that have been shown in preclinical and clinical studies to exert potent immunomodulatory, antifibrotic and regenerative actions in dystrophinopathy and heart failure. CDCs act by secreting extracellular vesicles known as exosomes, which target macrophages and alter their expression profile so that they adopt a healing, rather than a pro-inflammatory, phenotype.

• AGLE-102: Aegle Therapeutics
AGLE-102 is an investigational product comprised of extracellular vesicles isolated from allogeneic stem cells using Aegle's proprietary and patented methods. The product is a composite of native EVs and their associated complex assemblies of biologic molecules such as proteins, peptides, ligands and nucleic acids that have the potential to induce a wide variety of effects in recipient cells, including reducing inflammation, modulating the immune system and promoting regenerative healing.

• ILB-202: ILIAS Biologics
ILIAS's lead pipeline, ILB-202, is an exosome-based therapeutics containing the anti-inflammatory protein super-repressor lκB (srlκB). It is being developed for therapeutic use in inflammatory diseases, including acute and chronic ones. SrlκB, the dominant active form of lκBα, can attenuate inflammatory responses in various disease models by inhibiting the translocation of NF-κB into the nucleus. Conventional treatments targeted only upstream signaling pathways, while ILB-202 lowers the chance of off-target effects by directly targeting cytosolic core inflammation signals.

• ExoAAV: Evox Therapeutics
Evox is developing an exosome-delivered AAV encoding the phenylalanine hydroxylase (PAH) enzyme, which may have several significant advantages over other gene therapy approaches. Exosome-delivered AAV significantly improves cellular delivery and increases transgene expression in animals, thereby lowering the AAV dose needed. Exosome-delivered AAV demonstrates resistance to neutralizing antibodies in animal models suggesting that repeat dosing may be possible. The drug is under preclinical stage of development for the treatment of and cardiovascular diseases.

Exosomes Pipeline Therapeutics Assessment
There are approx. 66+ key companies which are developing the therapies for Exosomes. The Exosomes Companies which have their Exosomes drug candidates in the most advanced stage, i.e. phase III include, Capricor.

DelveInsight's Exosomes pipeline report covers around 110+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Exosomes pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Intra-articular
• Intraocular
• Intrathecal
• Intravenous
• Ophthalmic
• Oral
• Parenteral
• Subcutaneous
• Topical
• Transdermal

Exosomes Products have been categorized under various Molecule types such as
• Oligonucleotide
• Peptide
• Small molecule

Learn more about the emerging Exosomes Pipeline Therapies @ Exosomes Clinical Trials Assessment- https://www.delveinsight.com/sample-request/exosomes-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Exosomes Pipeline Report
• Coverage- Global
• Exosomes Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Exosomes Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Exosomes Companies- Capricor Therapeutics, Direct Biologics, Regeneus, OBCTCD24, AVEM HealthCare, Cellular Biomedicine Group, Aegle Therapeutics, Organicell Regenerative Medicine, Codiak BioSciences, Cellular Biomedicine Group, StemXO Therapeutics, Cells for Cells, RION, Cell Care Therapeutics, Novadip, Ilias, ReNeuron, Evora Bioscineces, Coya Therapeutics, ShiftBio Inc., Exostemtech, Celularity, Azymus Therapeutics, and others.
• Exosomes Pipeline Therapies- Exosome ointment, EV-Pure™, Zofin, Olmutinib, and others.

Dive deep into rich insights for new drugs for Exosomes Treatment, Visit @ Exosomes Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/exosomes-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Exosomes: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Exosomes- DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. CAP-1002: Capricor
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. Progenza: Regeneus
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. StemXO Endosome Therapy: Stem XO Therapeutics
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Exo-101: Exogenus Therapeutics
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Exosome - Collaborations Assessment- Licensing / Partnering / Funding
21. Exosomes- Unmet Needs
22. Exosomes- Market Drivers and Barriers
23. Appendix

For further information on the Exosomes pipeline therapeutics, reach out @ Exosomes Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/exosomes-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

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