Hepatic Encephalopathy Market 2024 - By Size, Share Analysis, Trends And Growth Forecast By 2033

The hepatic encephalopathy market size has grown strongly in recent years. It will grow from $1.62 billion in 2023 to $1.72 billion in 2024 at a compound annual growth rate (CAGR) of 6.0%. The growth in the historic period can be attributed to prevalence of liver diseases, growing awareness about hepatic encephalopathy, government initiatives, increasing new liver therapies.

The hepatic encephalopathy market size is expected to see strong growth in the next few years. It will grow to $2.1 billion in 2028 at a compound annual growth rate (CAGR) of 5.2%. The growth in the forecast period can be attributed to increasing ageing population, surge in treatment options, rising expenditure on healthcare infrastructure, investments on hepatic encephalopathy treatments. Major trends in the forecast period include launch of emerging therapies, research and clinical trials, advances in liver transplantation, pharmaceutical innovations, advances in nutrition and dietary management, adption of telemedicine and remote monitoring.

Market Overview -
Hepatic encephalopathy is a condition characterized by a decline in brain function resulting from severe liver disease. It is a reversible syndrome of impaired brain function in patients with advanced liver diseases. Treating hepatic encephalopathy (HE) involves managing the underlying liver disease, reducing ammonia levels in the blood and addressing neurological symptoms.

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Rising Prevalence Of Liver Diseases Fuels Growth In The Hepatic Encephalopathy Market
The growing prevalence of liver diseases is expected to propel the growth of the hepatic encephalopathy market going forward. Liver disease is a medical condition affecting the liver and impairing its function. Liver disease treatments such as hepatic encephalopathy can alleviate symptoms, slow disease progression, improve liver function and reduce hepatic encephalopathy occurrences by improving the management of underlying conditions, potentially reducing frequency and severity and enhancing patients' overall quality of life. For instance, in March 2023, according to the Office For Health Improvement And Disparities, a UK-based government organization, premature deaths from liver disease increased by 3.7% in 2021 from 10,501 to 10,127 in 2020. Therefore, the growing prevalence of liver diseases drives the hepatic encephalopathy market.

Competitive Landscape -
Major players in the hepatic encephalopathy market are Umecrine Cognition AB, Bausch Health Companies Inc., Mallinckrodt Pharmaceuticals, Lupin Limited, Salix Pharmaceuticals, Norgine B.V., Ferring B.V., ASKA Pharmaceutical Co. Ltd., Vedanta Biosciences Inc., Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Mylan N.V., Bausch Health Companies Inc., Ochsner Health Inc., Sun Pharmaceutical Industries Ltd., Dr. Reddy's Laboratories Ltd., Cipla Limited, Amneal Pharmaceuticals LLC, Mallinckrodt PLC, Lupin Limited, Torrent Pharmaceuticals Ltd., Salix Pharmaceuticals Inc., ASKA Pharmaceutical Co. Ltd., Norgine B.V.

Innovative Drug Development Drives Competition In The Hepatic Encephalopathy Market
Major companies operating in the hepatic encephalopathy market are developing innovative drugs to treat hepatic encephalopathy to gain competitive advantages and strengthen their position in the market. For instance, in June 2023, Karolinska Development AB, a Sweden-based pharmaceutical company, developed the novel GR3027 (golexanolone) to treat hepatic encephalopathy. This is an orally administered small molecule and a GABAA-receptor-modulating steroid antagonist (GAMSA) designed to antagonize positive GABAA-receptor modulation by endogenous neuroactive steroids. Additionally, the drug is being investigated for HE. The trial is being conducted for CHE in Phases I/IIa.

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Key Segments -
The hepatic encephalopathy market covered in this report is segmented -
1) By Drug Class: Antibiotics; Laxatives; L-Ornithine; L-Aspartate; Other Drug Classes
2) By Route Of Administration: Oral; Intravenous; Rectal 
3) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies

Key highlights covered in the report -
1. Detailed market size forecast and historical data analysis
2. Key drivers influencing market growth
3. Identification of upcoming trends and potential opportunities in the market
4. Analysis of major players strategies, to understand competitive dynamics and market positioning
5. Evaluation of regional dynamics

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