Chronic Refractory Cough Market Forecast 2034: FDA, EMA, PDMA Approvals, Clinical Trials, Epidemiology, Therapies, and Companies by DelveInsight

DelveInsight's report titled "Chronic Refractory Cough Market Insights, Epidemiology, and Market Forecast - 2034" comprehensively analyzes Chronic Refractory Cough (CRC). The report provides a comprehensive analysis of historical and projected epidemiological data, covering 12-month Prevalent Cases of Chronic Cough (CC), Gender-specific Cases of Chronic Cough (CC), Total Diagnosed Prevalent Cases of Chronic Refractory Cough (CRC), and Diagnosed Prevalent Cases of Chronic Cough in Idiopathic Pulmonary Fibrosis (IPF).

Key Takeaways from the Chronic Refractory Cough Market Research Report
• According to assessments conducted by DelveInsight's analysts, it was estimated that more than 12 million cases represented the total diagnosed prevalent cases of CRC across the 7MM in 2023. Within the 7MM, the United States recorded the highest number of diagnosed prevalent cases of CRC in 2023, followed by Japan. The prevalent population for CRC was determined based on the patient pool of CC.
• In the US, gender-specific cases of CC in 2023 were comprised of approximately 40% males and 60% females, with projections indicating an increase by the year 2034.
• The leading Chronic Refractory Cough Companies working in the market include Merck & Co, Kyorin Pharmaceuticals, NeRRe Therapeutics, Bellus Health, Shionogi, Axalbion, Aldeyra Therapeutics and others.
• Promising Chronic Refractory Cough Therapies in the various stages of development include Nalbuphine ER, BLU-5937, PA101, Gefapixant, and others.
• May 2024:- Stuart Mazzone- The Effect of Acute and Prolonged Administration of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough. The study will recruit 31 participants with existing chronic cough and investigate their brain responses using non-invasive magnetic resonance imaging while briefly breathing personally tailored stimuli that are just below threshold for triggering coughing (determined using inhaled cough challenge testing procedures). Brain scans will be performed before and at two time points (3 days and 12 weeks) after starting Gefapixant treatment, consisting of one 45mg tablet swallowed twice daily.
• May 2024:- Trevi Therapeutics- A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Two-Period Crossover Efficacy and Safety Study of Nalbuphine ER Tablets for the Treatment of Refractory Chronic Cough. A 2-period crossover study for the treatment of cough in patients with Refractory Chronic Cough via Nalbuphine ER (NAL ER). Each period will last 21 days and are separated by 21 days. Subjects will be randomized in Treatment Period 1 to either NAL ER or matching placebo and evaluated for 21 days. After completion of the first phase, subjects who received NAL ER will crossover to placebo and subjects who received placebo will crossover to NAL ER to complete Treatment Period 2.

Discover which therapies are expected to grab the Chronic Refractory Cough Market Share @ Chronic Refractory Cough Market Outlook- https://www.delveinsight.com/sample-request/chronic-refractory-cough-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Chronic Refractory Cough Overview
Chronic refractory cough refers to a persistent cough that does not respond to standard medical treatments. It's a condition where the cough persists for an extended period, typically defined as more than eight weeks, despite attempts to treat the underlying cause.

Chronic Refractory Cough treatment often involves addressing any underlying conditions contributing to the cough, such as treating asthma or GERD, and sometimes requires a multidisciplinary approach involving specialists such as pulmonologists, allergists, or gastroenterologists. Additionally, cough suppressants or other medications may be prescribed to help manage symptoms.

Chronic Refractory Cough Epidemiology Insights
The epidemiology section on Chronic Refractory Cough (CRC) offers an analysis of past and present patient populations, along with projected trends across seven major countries (7MM). Drawing from multiple studies and expert opinions, it aims to elucidate the underlying factors driving current and anticipated trends. Additionally, this segment of the report presents data on the diagnosed patient population, highlighting trends and underlying assumptions.

Learn more about Chronic Refractory Cough treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ https://www.delveinsight.com/sample-request/chronic-refractory-cough-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Chronic Refractory Cough Emerging Drugs Profile

• Gefapixant (MK-7264): Merck & Co/ Kyorin Pharmaceuticals
MK-7264 (gefapixant), being developed by Merck is a selective, non-narcotic, orally administered P2X3 antagonist designed to target the mechanism by which certain nerve fibers become hypersensitized and can lead to chronic and debilitating symptoms, such as CC. It is a selective P2X3 receptor antagonist that prevents ATP binding, which has a significant role in the activation of the sensory fibers central to cough initiation. Thus MK‐7264 exerts its antagonism via negative allosteric modulation.

• Camlipixant (BLU-5937): Bellus Health- a GSK company
Camlipixant (formerly known as BLU-5937), being developed by Bellus Health- a GSK company, is a potent, highly selective, oral antagonist of the P2X3 receptor, a clinically validated target for CC. BLU-5937 has the potential to be a best-in-class therapeutic for CRC patients, as it has shown to be highly selective (>1500-fold) for human P2X3 receptors versus P2X2/3 receptors. Bellus Health has completed Phase IIb (SOOTHE) trials and is currently being investigated in Phase III trials.

Chronic Refractory Cough Market Outlook
The Chronic Refractory Cough (CRC) market currently faces a significant challenge with the absence of approved therapies, leaving patients with a critical unmet need. Non-pharmacologic interventions, particularly Speech Therapy and Physiotherapy, represent the cornerstone of current treatment strategies. After nonpharmacological therapies, the market holds various types of pharmacologic therapies which include neuromodulators, proton pump inhibitors, ICS, and other treatment options. Neuromodulators include opiates (morphine, codeine, etc.), gabapentin, pregabalin, morphine, amitriptyline, and baclofen, which act on the heightened neural sensitization that is involved in the pathogenesis of CRC.

To learn more about Chronic Refractory Cough treatment guidelines, visit @ Chronic Refractory Cough Treatment Market Landscape- https://www.delveinsight.com/sample-request/chronic-refractory-cough-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Chronic Refractory Cough Drugs Market
The Chronic Refractory Cough Drugs Market is expected to witness substantial growth in the coming years as more targeted therapies receive regulatory approval and enter clinical practice. Additionally, ongoing research efforts aimed at better understanding the molecular mechanisms underlying Chronic Refractory Cough signaling likely to uncover new therapeutic targets and further expand treatment options for patients.

Chronic Refractory Cough Treatment Market Landscape
The Chronic Refractory Cough treatment market landscape has witnessed significant advancements over the past years, with targeted therapies playing a crucial role in improving outcomes for patients. Among these targeted therapies, the emergence of Chronic Refractory Cough has garnered attention in the medical community, presenting both challenges and opportunities in treatment strategies.

Learn more about the FDA-approved drugs for Chronic Refractory Cough @ Drugs for Chronic Refractory Cough Treatment- https://www.delveinsight.com/sample-request/chronic-refractory-cough-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Chronic Refractory Cough Market Report
• Coverage- 7MM
• Chronic Refractory Cough Companies- Merck & Co, Kyorin Pharmaceuticals, NeRRe Therapeutics, Bellus Health, Shionogi, Axalbion, Aldeyra Therapeutics and others.
• Chronic Refractory Cough Therapies in the various stages of development include Nalbuphine ER, BLU-5937, PA101, Gefapixant, and others.
• Chronic Refractory Cough Market Dynamics: Chronic Refractory Cough Market Drivers and Barriers
• Chronic Refractory Cough Market Access and Reimbursement, Unmet Needs and Future Perspectives

Discover more about Chronic Refractory Cough Drugs in development @ Chronic Refractory Cough Clinical Trials Assessment- https://www.delveinsight.com/sample-request/chronic-refractory-cough-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1 Key Insights
2 Report Introduction
3 CRC Market Overview at a Glance
4 CRC Epidemiology and Market Methodology
5 Executive Summary of CRC
6 Key Events
7 Disease Background and Overview
8 Epidemiology and Patient Population
9 Patient Journey
10 Emerging Drugs
11 CRC: The Seven Major Market Analysis
12 Key Opinion Leader's Views
13 SWOT Analysis
14 Unmet Needs
15 Reimbursement and Market Access
16 Appendix
17 DelveInsight Capabilities
18 Disclaimer
19 About DelveInsight

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