Advanced Hepatocellular Carcinoma Pipeline Outlook Report 2024 (Updated)

DelveInsight's, "Advanced Hepatocellular Carcinoma Pipeline Insight 2024" report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in the Advanced Hepatocellular Carcinoma pipeline landscape. It covers the Advanced Hepatocellular Carcinoma pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Advanced Hepatocellular Carcinoma pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Advanced Hepatocellular Carcinoma Pipeline Report
• DelveInsight's Advanced Hepatocellular Carcinoma pipeline report depicts a robust space with 50+ active players working to develop 50+ pipeline therapies for Advanced Hepatocellular Carcinoma treatment.
• The leading companies working in the Advanced Hepatocellular Carcinoma market include CStone Pharmaceuticals, TaiRx, Yiviva, AVEO Oncology, Eureka Therapeutics, Shanghai Henlius Biotech, Innovent Biologics, Akesobio, BeiGene, Zai Lab (Shanghai) Co., Geneos Therapeutics, Adaptimmune Therapeutics, and others.
• Promising Advanced Hepatocellular Carcinoma Pipeline Therapies in the various stages of development include Enzalutamide, ABT-869, Durvalumab, Tremelimumab, Penpulimab injection, TQB2618 injection, Anlotinib Hydrochloride Capsules, Donafenib Tosilate Tablets, Toripalimab Injection, IBI308 200mg, Lenvatinib, Pembrolizumab, Cabozantinib, AEG35156 antisense IV infusion, Sorafenib, Z-208, Octreotide, and others.

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The Advanced Hepatocellular Carcinoma pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage Advanced Hepatocellular Carcinoma drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the Advanced Hepatocellular Carcinoma clinical trial landscape.

Advanced Hepatocellular Carcinoma Overview
Hepatocellular carcinoma (HCC) is an aggressive malignancy, resulting as the third cause of death by cancer each year. Unfortunately, considerable number of patients are diagnosed at advanced stage unsuitable for surgery or local treatment with poor prognosis and a median overall survival (OS) of about 6 months.

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Advanced Hepatocellular Carcinoma Emerging Drugs Profile

• Tivozanib : AVEO Oncology
FOTIVDA® (tivozanib) is an oral, once-daily, differentiated vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor (TKI). It is a potent, selective inhibitor of VEGFRs 1, 2, and 3 with a long half-life designed to improve efficacy and tolerability. Tivozanib has been shown to significantly reduce regulatory T-cell production in preclinical models. Currently, Tivozanib is being evaluated in Phase I/II stage of clinical trial evaluation for the treatment of advanced hepatocellular carcinoma.

• Nofazinlimab: CStone Pharmaceuticals
CS1003 is a humanized recombinant IgG4 monoclonal antibody targeting human programmed cell death protein 1 (PD-1) being developed for immunotherapy of various tumors. Compared to most of the monoclonal antibodies that bind human and monkey PD-1(either already approved or in clinical stage) , CS1003 demonstrates comparable high binding affinities across species against human, cynomolgus monkey and mouse PD-1, and is developed to disrupt the interaction of PD-1 with its ligands PD-L1 and PD-L2 . CS1003 is also unique in that it can simultaneously recognize human and mouse PD-1, which allows fast pre-clinical proof of concept for CS1003 in combination with novel targeted therapies using syngeneic mouse tumor models. Currently, the drug is being developed in Phase III stage of development for the treatment of advanced hepatocellular carcinoma.

• ECT 204: Eureka Therapeutics
ECT204, a GPC3 targeting ARTEMIS® T-cell therapy for the treatment of hepatocellular carcinoma (HCC), the predominant type of liver cancer. Glypican 3 (GPC3) is a promising target for HCC therapies and is found in more than 70% of HCC cells. The GPC3 protein is also expressed in other solid tumors including ovarian and lung cancer. Currently, the drug is in Phase I/II stage of Clinical trial evaluation for the treatment of advanced hepatocellular carcinoma.

• Sintilimab: Eli Lilly and Company/Innovent
Sintilimab is an immunoglobulin G4 monoclonal antibody, which binds to PD-1 molecules on the surface of T-cells, blocks the PD-1 / PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells. Innovent is currently conducting more than 20 clinical studies of sintilimab worldwide, to evaluate its safety and efficacy in a wide variety of cancer indications, including more than 10 registrational or pivotal clinical trials. Sintilimab, marketed as TYVYT® (sintilimab injection) in China, is an innovative PD-1 inhibitor with global quality standards jointly developed by Innovent and Eli Lilly and Company. Currently, the drug is being developed in Phase I stage of Clinical trial evaluation for the treatment of advanced hepatocellular carcinoma.

Advanced Hepatocellular Carcinoma Therapeutics Assessment
There are approx. 50+ key companies which are developing the therapies for Advanced Hepatocellular Carcinoma. The Advanced Hepatocellular Carcinoma companies which have their Advanced Hepatocellular Carcinoma drug candidates in the most advanced stage, i.e. phase III include, CStone Pharmaceuticals.

DelveInsight's Advanced Hepatocellular Carcinoma pipeline report covers around 50+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Advanced Hepatocellular Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Intra-articular
• Intraocular
• Intrathecal
• Intravenous
• Ophthalmic
• Oral
• Parenteral
• Subcutaneous
• Topical
• Transdermal

Advanced Hepatocellular Carcinoma Products have been categorized under various Molecule types such as
• Oligonucleotide
• Peptide
• Small molecule

Learn more about the emerging Advanced Hepatocellular Carcinoma Pipeline Therapies @ Advanced Hepatocellular Carcinoma Clinical Trials Assessment- https://www.delveinsight.com/sample-request/advanced-hepatocellular-carcinoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Advanced Hepatocellular Carcinoma Pipeline Report
• Coverage- Global
• Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Advanced Hepatocellular Carcinoma Companies- CStone Pharmaceuticals, TaiRx, Yiviva, AVEO Oncology, Eureka Therapeutics, Shanghai Henlius Biotech, Innovent Biologics, Akesobio, BeiGene, Zai Lab (Shanghai) Co., Geneos Therapeutics, Adaptimmune Therapeutics, and others.
• Advanced Hepatocellular Carcinoma Pipeline Therapies- Enzalutamide, ABT-869, Durvalumab, Tremelimumab, Penpulimab injection, TQB2618 injection, Anlotinib Hydrochloride Capsules, Donafenib Tosilate Tablets, Toripalimab Injection, IBI308 200mg, Lenvatinib, Pembrolizumab, Cabozantinib, AEG35156 antisense IV infusion, Sorafenib, Z-208, Octreotide, and others.

Dive deep into rich insights for new drugs for Advanced Hepatocellular Carcinoma treatment, Visit @ Advanced Hepatocellular Carcinoma Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/advanced-hepatocellular-carcinoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Advanced Hepatocellular Carcinoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Advanced Hepatocellular Carcinoma- DelveInsight's Analytical Perspective
7. Late Stage Products (Pre-Registration)
8. Drug name: Company Name
9. Drug profiles in the detailed report…..
10. Last Stage Products (Phase III)
11. Nofazinlimab: CStone Pharmaceuticals
12. Drug profiles in the detailed report…..
13. Mid Stage Products (Phase I/II)
14. Tivozanib : AVEO Oncology
15. Drug profiles in the detailed report…..
16. Preclinical and Discovery Stage Products
17. Drug name: Company name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Advanced Hepatocellular Carcinoma Key Companies
21. Advanced Hepatocellular Carcinoma Key Products
22. Advanced Hepatocellular Carcinoma - Unmet Needs
23. Advanced Hepatocellular Carcinoma - Market Drivers and Barriers
24. Advanced Hepatocellular Carcinoma - Future Perspectives and Conclusion
25. Advanced Hepatocellular Carcinoma Analyst Views
26. Advanced Hepatocellular Carcinoma Key Companies
27. Appendix

For further information on the Advanced Hepatocellular Carcinoma Pipeline Therapeutics, reach out to Advanced Hepatocellular Carcinoma Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/advanced-hepatocellular-carcinoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

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About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

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This release was published on openPR.