Diabetic Retinopathy Pipeline Outlook Report 2024 (Updated)

DelveInsight's, "Diffuse Large B-Cell Lymphoma Pipeline Insight 2024" report provides comprehensive insights about 80+ Diffuse Large B Cell Lymphoma companies and 80+ Diffuse Large B Cell Lymphoma pipeline drugs in Diffuse Large B-Cell Lymphoma pipeline landscape. It covers the Diffuse Large B Cell Lymphoma pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Diffuse Large B Cell Lymphoma Pipeline Report
• DelveInsight's Diffuse Large B Cell Lymphoma pipeline report depicts a robust space with 80+ active players working to develop 80+ pipeline therapies for Diabetic Retinopathy treatment.
• Several prominent Diffuse Large B Cell Lymphoma companies are actively involved in the market, including Genmab, Roche, Acerta Pharma, Autolus, Xynomic Pharmaceuticals, Genentech, Celgene, AbbVie, Mabion, Pharmacyclics LLC, Shanghai Yingli Pharmaceutical, Philogen, Amgen, Chia Tai Tianqing Pharmaceutical Group Co., Ltd., JW Therapeutics, Incyte Corporation, BeiGene, Miltenyi Biotec GmbH, Beijing InnoCare PharmaTech Co., Ltd., Bristol-Myers Squibb, Celleron Therapeutics, Otsuka Pharmaceutical, Curis, Inc., Bayer, Kartos Therapeutics, Inc., Shanghai Institute of Biological Products, Novartis Pharmaceuticals, Constellation Pharmaceuticals, SecuraBio, Inc., CytomX Therapeutics, Juno Therapeutics, Teneobio, Inc., Telios Pharma, Inc., Sorrento Therapeutics, Inc., Curocell Inc., TG Therapeutics, Inc., Tessa Therapeutics, TCR2 Therapeutics, Plexxikon, Shattuck Labs, Inc., MEI Pharma, Inc., Boryung Pharmaceutical Co., Ltd., Sutro Biopharma, Inc., Newave Pharmaceutical Inc., Eden BioCell Ltd., Adicet Bio, Inc., Velos Bio Inc., Seagen Inc., Eisai Co Ltd, Nurix Therapeutics, Inc., Prelude Therapeutics, Xencor and others.
• Promising Diffuse Large B Cell Lymphoma Pipeline Therapies in the various stages of development include Epcoritamab, Cyclophosphamide, Rituximab, Lenalidomide, maplirpacept (PF-07901801), and others.
• April 2024: Pfizer announced a study of Phase 2 clinical trials for Maplirpacept, Tafasitamab and Lenalidomide. The purpose of this study is to learn about the effects of three study medicines [maplirpacept (PF-07901801), tafasitamab, and lenalidomide] when given together for the treatment of diffuse large B-cell lymphoma (DLBCL) that is relapsed (has returned after last treatment) or is refractory (has not responded to last treatment).
• April 2024: Sichuan Baili Pharmaceutical Co., Ltd. announced a study of Phase 1 & 2 clinical trials for GNC-038. In this study, the safety and preliminary efficacy of GNC-038 in participants with recurrent or refractory Diffuse Large B-cell lymphoma (DLBCL) will be investigated to assess the dose-limiting toxicity (DLT), maximum tolerated dose (MTD) or maximum administered dose (MAD) for MTD is not reached of GNC-038. The recommended dose for phase II (RP2D) clinical study will also be determined.

Request a sample and discover the recent advances in Diffuse Large B Cell Lymphoma Treatment Drugs @ Diffuse Large B Cell Lymphoma Pipeline Outlook Report- https://www.delveinsight.com/sample-request/diffuse-large-b-cell-lymphoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

In the Diffuse Large B Cell Lymphoma pipeline report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Diffuse Large B Cell Lymphoma collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Diffuse Large B Cell Lymphoma Overview
Diffuse Large B-Cell Lymphoma (DLBCL) is a type of non-Hodgkin lymphoma (NHL). NHL is a cancer of the lymphatic system. It develops when the body makes abnormal B lymphocytes. These lymphocytes are a type of white blood cell that normally help to fight infections.

Find out more about Diffuse Large B Cell Lymphoma Therapeutics Assessment @ Diffuse Large B Cell Lymphoma Preclinical and Discovery Stage Products- https://www.delveinsight.com/sample-request/diffuse-large-b-cell-lymphoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Diabetic Retinopathy Emerging Drugs Profile

• Epcoritamab: Genmab
Epcoritamab is an investigational IgG1-bispecific antibody created using Genmab's proprietary DuoBody technology. Genmab's DuoBody-CD3 technology is designed to direct cytotoxic T cells selectively to tumors to elicit an immune response towards malignant cells. Epcoritamab is designed to simultaneously bind to CD3 on T cells and CD20 on B cells and induces T cell mediated killing of lymphoma B cells. CD20 is a clinically validated therapeutic target, and is expressed on many B-cell malignancies, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma and chronic lymphocytic leukemia. Epcoritamab is being co-developed by Genmab and AbbVie as part of the companies' broad oncology collaboration. Currently, it is in phase 3 stage of development for the treatment of Diffuse Large B-Cell Lymphoma.

• Glofitamab: Roche
Glofitamab is an investigational CD20xCD3 T-cell engaging bispecific antibody designed to target CD20 on the surface of B-cells and CD3 on the surface of T-cells. This dual targeting activates and redirects a patient's existing T-cells to engage and eliminate target B-cells by releasing cytotoxic proteins into the B-cells. Glofitamab is based on a novel structural format which we call '2:1', which refers to the structure of the antibody. It is engineered to have two 'Fab' regions which bind to CD20, and one 'Fab' region which binds to CD3. A robust clinical development programme for glofitamab is ongoing, investigating the molecule as a monotherapy and in combination with other medicines, for the treatment of people with CD20-positive B-cell non-Hodgkin lymphomas, including diffuse large B-cell lymphoma and follicular lymphoma, and other blood cancers.

• Acalabrutinib: Acerta Pharma
Acalabrutinib is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, acalabrutinib inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B lymphocyte development, activation, signaling, proliferation and survival.

• AUTO 3: Autolus
AUTO3 is a programmed T cell therapy containing two independent chimeric antigen receptors targeting CD19 and CD22 that have each been independently optimized for single target activity. By simultaneously targeting two B cell antigens, AUTO3 is designed to minimize relapse due to single antigen loss in patients with B cell malignancies. AUTO3 is currently in phase I/II stage of development for the treatment of Diffuse Large B-Cell Lymphoma.

• Abexinostat: Xynomic Pharmaceuticals
Abexinostat (Xynomic Pharmaceuticals) is a broad histone deacetylase (HDAC) inhibitor. HDAC enzymes (also known as lysine deacetylase) cleave acetyl groups from N-acetyl lysine amino acids on a histone. HDAC inhibition leads to highly acetylated histones and chromatin reshaping. In addition to altering histone acetylation, HDAC inhibitors can also influence the degree of acetylation on non-histone proteins, increasing or repressing their activity. Currently, it is in phase 2 stage of development for the treatment of Diffuse Large B-Cell Lymphoma.

Diffuse Large B Cell Lymphoma Therapeutics Assessment
There are approx. 80+ key Diffuse Large B Cell Lymphoma companies which are developing the Diffuse Large B Cell Lymphoma therapies. The Diffuse Large B Cell Lymphoma companies which have their Diffuse Large B-Cell Lymphoma drug candidates in the most advanced stage, i.e. phase III include, Genmab.


DelveInsight's Diffuse Large B Cell Lymphoma Pipeline Report covers around 80+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Diffuse Large B-Cell Lymphoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• Intravenous
• Subcutaneous
• Topical.
• Molecule Type

Diffuse Large B Cell Lymphoma Pipeline Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy
• Product Type

Learn more about the emerging Diffuse Large B Cell Lymphoma Pipeline Therapies @ Diffuse Large B Cell Lymphoma Clinical Trials Assessment- https://www.delveinsight.com/sample-request/diffuse-large-b-cell-lymphoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Diabetic Retinopathy Pipeline Report
• Coverage- Global
• Diffuse Large B Cell Lymphoma Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Diffuse Large B Cell Lymphoma Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Diffuse Large B Cell Lymphoma Companies- Genmab, Roche, Acerta Pharma, Autolus, Xynomic Pharmaceuticals, Genentech, Celgene, AbbVie, Mabion, Pharmacyclics LLC, Shanghai Yingli Pharmaceutical, Philogen, Amgen, Chia Tai Tianqing Pharmaceutical Group Co., Ltd., JW Therapeutics, Incyte Corporation, BeiGene, Miltenyi Biotec GmbH, Beijing InnoCare PharmaTech Co., Ltd., Bristol-Myers Squibb, Celleron Therapeutics, Otsuka Pharmaceutical, Curis, Inc., Bayer, Kartos Therapeutics, Inc., Shanghai Institute of Biological Products, Novartis Pharmaceuticals, Constellation Pharmaceuticals, SecuraBio, Inc., CytomX Therapeutics, Juno Therapeutics, Teneobio, Inc., Telios Pharma, Inc., Sorrento Therapeutics, Inc., Curocell Inc., TG Therapeutics, Inc., Tessa Therapeutics, TCR2 Therapeutics, Plexxikon, Shattuck Labs, Inc., MEI Pharma, Inc., Boryung Pharmaceutical Co., Ltd., Sutro Biopharma, Inc., Newave Pharmaceutical Inc., Eden BioCell Ltd., Adicet Bio, Inc., Velos Bio Inc., Seagen Inc., Eisai Co Ltd, Nurix Therapeutics, Inc., Prelude Therapeutics, Xencor and others.
• Diffuse Large B Cell Lymphoma Pipeline Therapies- Epcoritamab, Cyclophosphamide, Rituximab, Lenalidomide, maplirpacept (PF-07901801), and others.

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Table of Content
1. Introduction
2. Executive Summary
3. Diffuse Large B-Cell Lymphoma: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Diffuse Large B-Cell Lymphoma - DelveInsight's Analytical Perspective
7. In-depth Commercial Assessment
8. Diffuse Large B-Cell Lymphoma Collaboration Deals
9. Late Stage Products (Phase III)
10. Epcoritamab: Genmab
11. Drug profiles in the detailed report…..
12. Mid Stage Products (Phase II)
13. Abexinostat: Xynomic Pharmaceuticals
14. Drug profiles in the detailed report…..
15. Early Stage Products (Phase I/II)
16. AUTO 3: Autolus
17. Drug profiles in the detailed report…..
18. Inactive Products
19. Diffuse Large B-Cell Lymphoma Key Companies
20. Diffuse Large B-Cell Lymphoma Key Products
21. Diffuse Large B-Cell Lymphoma- Unmet Needs
22. Diffuse Large B-Cell Lymphoma- Market Drivers and Barriers
23. Diffuse Large B-Cell Lymphoma- Future Perspectives and Conclusion
24. Diffuse Large B-Cell Lymphoma Analyst Views
25. Diffuse Large B-Cell Lymphoma Key Companies
26. Appendix


For further information on the Diffuse Large B Cell Lymphoma Pipeline therapeutics, reach out to Diffuse Large B Cell Lymphoma Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/diffuse-large-b-cell-lymphoma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

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About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

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