Global Plasma Protein Therapeutics Market Driven by Introduction of New Plasma-Derived Therapies

Plasma protein therapies are a unique set of therapies that treat well-defined medical conditions by replacing either deficient or missing proteins found in plasma, allowing patients to lead more productive and healthier lives. Plasma protein therapeutics, which involves plasma-derived therapies and their recombinant analogs, are biologic medicines either injected or infused to treat life-threatening, genetic, and chronic diseases. Owing to the differences in production and processing methods, each therapy has a distinct biochemical profile, which leads to distinct clinical responses among patients and also results in a varied level of efficacy.

The key product types of the plasma protein therapeutics include immunoglobulin, coagulation factors, albumin, and alpha-1 proteinase inhibitor. Immunoglobulins can be subcutaneous, intravenous, or hyperimmunoglobulins. Geographically, the global plasma protein therapeutics market comprises Europe, North America, Asia Pacific, and Rest of the World.

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The global plasma protein therapeutics market is driven by a host of factors, including the introduction of new plasma-derived therapies, the rising use of plasma-proteins-derived medicines, an advancement in the technologies involved in cost-effective and efficient fractionating processes, the surge in blood donations especially in high-income countries, growing awareness regarding the significance of blood donation, and the increasing presence of favorable government initiatives for the development of plasma-derived medicines.

In addition to these, the growing prevalence of more than 200 life-threatening diseases affecting the neurological or immune system, such as idiopathic thrombocytopenic purpura (ITP), chronic inflammatory demyelinating polyneuropathy (CIPD), multifocal motor neuropathy (MMN), and infectious diseases such as rabies, hepatitis A and B, varicella, and tetanus is also a major driving force for the global plasma protein therapeutics market.

Immunoglobulins hold a significant share in the overall plasma protein therapeutics market owing to their growing use in the treatment of rare genetic and other diseases. The rising prevalence of infectious diseases such as rabies, as well as several forms of primary and secondary immunodeficiencies, is also impacting the demand for immunoglobulins. The market for coagulation factors is also projected to gain impetus during the forecast period thanks to the rising applications of these factors in the treatment of conditions such as Von Willebrand disease and hepatitis A and B. Coagulation factors offer increased scope for new players entering the plasma protein therapeutics market.

The global market for plasma protein therapeutics is dominated by North America owing to the growing demand for plasma proteins and the region’s highest volume of blood collection. The Plasma Protein Therapeutics Association (PPTA) states that North America accounted for a share of over 40.0% in the global plasma protein therapeutics market in 2013, driven by the increasing presence of commercial organizations with advanced technologies in the field of fractionating, the growing awareness of people regarding regular blood donations, and the higher disposable income of the people. The introduction of recent techniques is projected to fuel the plasma protein therapeutics market in the coming years. The health department of the Government of Australia estimated that in 2010, the average plant capacities in North America was pegged at 1,144,000 liters, as against the global average of 475,000 liters.

The Asia Pacific market for plasma protein therapeutics is projected to gain momentum during the forecast period owing to rising awareness regarding blood donations. The World Health Organization states that during the 2004–2012 period, Southeast Asia saw a whopping 78.0% rise in the rate of blood donation. The growth in the APAC plasma protein therapeutics market can be attributed to the rise in awareness among health care practitioners, the increasing disposable income of the patients, and the surge in government initiatives related to the development of plasma protein medicines.

Grifols, Chengdu Inst., Telecris, Octapharma, Baxter, CSL Limited, and Kedrion are some of the leading players competing in the global plasma protein therapeutics market. Apart from this, there are a number of nonprofit organizations that have been playing a critical role in the expansion of the plasma protein therapeutics market. These include Sanquin (Netherlands), Japan Red Cross (Japan), LFB Group (France), Shanghai Institute of Blood (China), and BPL Group (the U.K.).

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