North America Synthetic Opioids Market Research and Scope: 2024, Explosive Growth Factors, Industry Statistics and Forecast to 2031 | Johnson & Johnson Services, Inc., Purdue Pharma L.P

Market Overview:

Synthetic opioids are man-made pain relievers that act on the central nervous system to produce an analgesic effect similar to morphine. Synthetic opioids like fentanyl and meperidine are primarily prescribed for severe pain management and end-of-life care.

Market Dynamics:

The North America synthetic opioids market is projected to witness high growth owing to the increasing prevalence of chronic pain disorders and rising elderly population who are more prone to orthopedic conditions. According to the Centers for Disease Control and Prevention, around 50 million adults in the US suffer from chronic pain. This rising disease burden isexpected to fuel the demand for opioids analgesics for pain management. Additionally,easy availability of synthetic opioids through online pharmacies and increasing misuse of prescription opioids is also anticipated to contribute to the market growth over the forecast period.

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Top Companies Covered In This Report: Johnson & Johnson Services, Inc., Purdue Pharma L.P., Hikma Pharmaceuticals PLC, AbbVie Inc., Sanofi, Sun Pharmaceutical Industries Ltd, Pfizer, Inc., AstraZeneca Plc., Mallinckrodt Pharmaceuticals, Teva Pharmaceutical Industries Ltd., Endo Pharmaceuticals Inc., and Boehringer Ingelheim International GmbH.

Market Segmentation:

North America Synthetic Opioids Market, By Product Type:
Synthetic Opioids
Methadone
Fentanyl
Meperidine
Semi Synthetic Opioids
Hydrocodane
Oxymorphone
Oxycodone
Hydromorphone
Buprenorphine

North America Synthetic Opioids Market, By Application:
Pain Management
De-Addiction

North America Synthetic Opioids Market, By Distribution Channel:
Retail Outlets
Hospitals

North America Synthetic Opioids Market Drivers: Rising aging population suffering from chronic and life-threatening diseases across North America

The aging population in North America, especially in the United States and Canada, who are suffering from chronic diseases is a major market driver for the synthetic opioids market. According to WHO, the population aged 60 years and over is growing at a rate of about 3% per year. As age advances, the risk of chronic diseases like cancer, diabetes etc increases. These chronic conditions often cause severe pain that requires long term pain management. Synthetic opioids are commonly prescribed for chronic pain conditions owing to their long lasting analgesic effects. Therefore, the rising burden of chronic diseases due to aging population is fueling the growth of synthetic opioids market in North America.

Increasing prevalence of cancer and approvals of new opioids for cancer pain management

Cancer is one of the leading causes of death in North America. According to American cancer society, over 1.8 million new cancer cases are diagnosed and 606,520 cancer deaths occur in the United States alone each year. Cancer pain management is a major healthcare challenge. Opioids remain the mainstay treatment option for managing moderate to severe cancer pain. Drug makers are focusing on developing new synthetic opioids with improved efficacy, safety and extended release formulations to manage cancer pain for long duration. For instance, in 2018, FDA approved Dsuvia (sufentanil) sublingual tablet for management of moderate-to-severe acute pain in medically supervised settings. Such ongoing approvals of novel synthetic opioids specifically for cancer pain will augment the market growth.

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North America Synthetic Opioids Market Restrain: Abuse potential and rising opioid epidemic across North America

Opioid misuse and abuse has severely impacted many communities and families across North America, especially in the United States. According to the National Institute of Drug Abuse (NIDA), opioid overdose killed more than 47,000 Americans in 2017 alone. Synthetic opioids like fentanyl are considered to be highly addictive. Illicit fentanyl is commonly mixed with and to increase their euphoric effects thereby contributing to the rising overdose deaths. In response to the worsening opioid epidemic, regulatory bodies are enforcing stricter rules for prescription practices of opioids. Many US states have also filed lawsuits against opioid manufacturers alleging their role in crisis. All these factors may restrain the inappropriate use of prescription synthetic opioids thereby hampering the overall market growth.

North America Synthetic Opioids Market Opportunity: Development of new alternative delivery formulations

Currently available synthetic opioids are primarily delivered orally or via parenteral route like injection. However, these conventional delivery modes have certain limitations like inter-patient variability in absorption, liver first pass effect, risk of diversion and abuse via parenteral route. There exists a lucrative opportunity for pharmaceutical companies to develop novel alternative delivery formulations of synthetic opioids with improved safety, efficacy and convenience. For instance, sublingual and intranasal formulations can enable rapid onset of analgesia avoiding hepatic first pass metabolism. Novel transdermal patches may deliver fentanyl continuously for 3 days or more. Development of such advanced delivery technologies can potentially expand appropriate usage of synthetic opioids, thereby addressing unmet needs of chronic pain patients as well as opioid epidemic to certain extent. This presents a major market opportunity for pharmaceutical manufacturers in North America synthetic opioids market.

North America Synthetic Opioids Market Trend: Growing preference for long acting, abuse-deterrent opioid formulations

In response to the public health crisis of opioid abuse and overdose deaths, regulatory agencies are pushing pharma companies to develop abuse-deterrent formulations of opioids that are difficult to abuse but still provide effective pain relief when used as directed. Long acting opioids with extended release mechanism are also preferred to cut down frequency of dosing and ensure round the clock analgesia thus improving patient compliance. Manufacturers are reformulating commercially available synthetic opioids like oxycodone, morphine, fentanyl using abuse-deterrent technologies like physical and chemical barriers, agonist-antagonist combinations, aversive agents etc. For example, FDA approved abuse-deterrent oxycodone HCl extended-release tablets (Xtampza ER) and Dsuvia (sufentanil) sublingual tablet incorporate features to reduce potential misuse and abuse through alternative routes like injection or inhalation. Such

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𝐅𝐀𝐐'𝐬

Q.1 What are the main factors influencing the North America Synthetic Opioids market?
Q.2 Which companies are the major sources in this industry?
Q.3 What are the market's opportunities, risks, and general structure?
Q.4 Which of the top North America Synthetic Opioids Market companies compare in terms of sales, revenue, and prices?
Q.5 Which businesses serve as the North America Synthetic Opioids market's distributors, traders, and dealers?
Q.6 How are market types and applications and deals, revenue, and value explored?
Q.7 What does a business area's assessment of agreements, income, and value implicate?

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