Autosomal Dominant Polycystic Kidney Disease Market | Galapagos NV, Reata Pharmaceuticals, Kadmon Pharmaceuticals, Sanofi, Anakuria Therapeutics, Regulus Therapeutics, AceLink Therapeutics, Healx, XORTX Therapeutics, Poxel, Alebund Pharmaceuticals, Chinoo

DelveInsight's "Autosomal Dominant Polycystic Kidney Disease Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of Autosomal Dominant Polycystic Kidney Disease, historical and forecasted epidemiology as well as the Autosomal Dominant Polycystic Kidney Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Autosomal Dominant Polycystic Kidney Disease market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Autosomal Dominant Polycystic Kidney Disease market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Autosomal Dominant Polycystic Kidney Disease treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Autosomal Dominant Polycystic Kidney Disease market.

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Autosomal Dominant Polycystic Kidney Disease: An Overview

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder characterized by the formation of multiple cysts in the kidneys. It's one of the most common inherited disorders affecting the kidneys.

Here are some key points about ADPKD:

Inheritance: ADPKD is an autosomal dominant disorder, meaning that if a person inherits one mutated copy of the gene responsible for the condition (PKD1 or PKD2), they will develop the disease.

Genetic Mutation: Mutations in the PKD1 or PKD2 genes cause ADPKD. The PKD1 gene mutation is more common and often leads to more severe symptoms.

Symptoms: The disease may remain asymptomatic for years. However, as cysts grow in the kidneys, they can lead to symptoms such as abdominal pain, high blood pressure, blood in urine, kidney stones, kidney infections, and eventually kidney failure.

Diagnosis: Imaging tests like ultrasounds, MRIs, or CT scans are used to detect cysts in the kidneys. Genetic testing can also help confirm the diagnosis in some cases, especially if there's a family history of ADPKD.

Treatment: Management focuses on controlling symptoms, slowing the progression of kidney damage, and preventing complications. This may involve medications to control blood pressure, pain management, and lifestyle changes. In advanced stages, dialysis or kidney transplantation might be necessary.

Prognosis: The progression of ADPKD varies among individuals. Some may have a relatively mild course with few symptoms, while others may experience rapid progression leading to kidney failure.

Genetic Counseling: Individuals with a family history of ADPKD might consider genetic counseling and testing to understand their risk of inheriting the disease and its implications for their health.

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Autosomal Dominant Polycystic Kidney Disease Market

"The Autosomal Dominant Polycystic Kidney Disease market size in seven major markets was USD 1,077 million in 2021, which is further expected to increase significantly by 2032 in the forecast period 2022─2032."

The Autosomal Dominant Polycystic Kidney Disease market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Autosomal Dominant Polycystic Kidney Disease market trends by analyzing the impact of current Autosomal Dominant Polycystic Kidney Disease therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

Otsuka Pharmaceuticals' tolvaptan (Jynarque/Jinarc/Samsca) stands as the solitary approved medication globally dedicated to treating adults grappling with ADPKD. Specifically designed for adults at risk of experiencing a swift progression of ADPKD, this drug operates by blocking vasopressin receptors in the kidneys, thereby reducing adenylate cyclase activity. This mechanism aids in slowing down the decline in kidney function.

Furthermore, Otsuka, in collaboration with the Mario Negri Institute for Pharmacological Research in Italy, has conducted trials to assess the effectiveness of combining tolvaptan with octreotide LAR. This combined therapy involves a vasopressin antagonist and somatostatin analog and has been studied in ADPKD patients exhibiting normal or hyperfiltration kidney function.

According to DelveInsight, the Autosomal Dominant Polycystic Kidney Disease market in 7MM is expected to witness a major change in the study period 2019-2032.

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Autosomal Dominant Polycystic Kidney Disease Epidemiology

The Autosomal Dominant Polycystic Kidney Disease epidemiology section provides insights into the historical and current Autosomal Dominant Polycystic Kidney Disease patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Autosomal Dominant Polycystic Kidney Disease market report also provides the diagnosed patient pool, trends, and assumptions.

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Autosomal Dominant Polycystic Kidney Disease Drugs Uptake

This section focuses on the uptake rate of the potential Autosomal Dominant Polycystic Kidney Disease drugs recently launched in the Autosomal Dominant Polycystic Kidney Disease market or expected to be launched in 2019-2032. The analysis covers the Autosomal Dominant Polycystic Kidney Disease market uptake by drugs, patient uptake by therapies, and sales of each drug.

Autosomal Dominant Polycystic Kidney Disease Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Autosomal Dominant Polycystic Kidney Disease market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Autosomal Dominant Polycystic Kidney Disease Pipeline Development Activities

The Autosomal Dominant Polycystic Kidney Disease report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Autosomal Dominant Polycystic Kidney Disease key players involved in developing targeted therapeutics.

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Autosomal Dominant Polycystic Kidney Disease Therapeutics Assessment

Major key companies such as Galapagos NV, Reata Pharmaceuticals, Kadmon Pharmaceuticals, Sanofi, Anakuria Therapeutics, Regulus Therapeutics, AceLink Therapeutics, Healx, XORTX Therapeutics, Poxel, Alebund Pharmaceuticals, Chinook Therapeutics, and others are working proactively in the Autosomal Dominant Polycystic Kidney Disease Therapeutics market to develop novel therapies which will drive the Autosomal Dominant Polycystic Kidney Disease treatment markets in the upcoming years.

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Autosomal Dominant Polycystic Kidney Disease Report Key Insights

1. Autosomal Dominant Polycystic Kidney Disease Patient Population
2. Autosomal Dominant Polycystic Kidney Disease Market Size and Trends
3. Key Cross Competition in the Autosomal Dominant Polycystic Kidney Disease Market
4. Autosomal Dominant Polycystic Kidney Disease Market Dynamics (Key Drivers and Barriers)
5. Autosomal Dominant Polycystic Kidney Disease Market Opportunities
6. Autosomal Dominant Polycystic Kidney Disease Therapeutic Approaches
7. Autosomal Dominant Polycystic Kidney Disease Pipeline Analysis
8. Autosomal Dominant Polycystic Kidney Disease Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Autosomal Dominant Polycystic Kidney Disease Market

Table of Contents

1. Key Insights
2. Executive Summary
3. Autosomal Dominant Polycystic Kidney Disease Competitive Intelligence Analysis
4. Autosomal Dominant Polycystic Kidney Disease Market Overview at a Glance
5. Autosomal Dominant Polycystic Kidney Disease Disease Background and Overview
6. Autosomal Dominant Polycystic Kidney Disease Patient Journey
7. Autosomal Dominant Polycystic Kidney Disease Epidemiology and Patient Population
8. Autosomal Dominant Polycystic Kidney Disease Treatment Algorithm, Current Treatment, and Medical Practices
9. Autosomal Dominant Polycystic Kidney Disease Unmet Needs
10. Key Endpoints of Autosomal Dominant Polycystic Kidney Disease Treatment
11. Autosomal Dominant Polycystic Kidney Disease Marketed Products
12. Autosomal Dominant Polycystic Kidney Disease Emerging Therapies
13. Autosomal Dominant Polycystic Kidney Disease Seven Major Market Analysis
14. Attribute Analysis
15. Autosomal Dominant Polycystic Kidney Disease Market Outlook (7 major markets)
16. Autosomal Dominant Polycystic Kidney Disease Access and Reimbursement Overview
17. KOL Views on the Autosomal Dominant Polycystic Kidney Disease Market
18. Autosomal Dominant Polycystic Kidney Disease Market Drivers
19. Autosomal Dominant Polycystic Kidney Disease Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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