Organoids Market Study, Competitive Strategies, Key Manufacturers, New Project Investment by 2030

According to our new research study on " Organoids Market Forecast to 2030 - COVID-19 Impact and Global Analysis - by Organ Type, Application, Source, and Type," the market is expected to grow from US$ 2,507.28 million in 2022 to US$ 12,206.15 million by 2030; it is estimated to register a CAGR of 21.9% from 2022 to 2030. The report highlights the key factors driving the organoids market growth and prominent players with their developments in the market.

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Based on the region, Asia Pacific is the fastest growing region in the organoids market. Among the countries accounted in the region for the study, Japan is holding the largest market share of the region in the organoids market.

Japan's rapidly aging population presents unique business opportunities in health sciences as older people need more medicine. The government is responding by easing different life science regulations and accelerating innovative new drugs to promote current pharma companies, both domestic and foreign, and attract new companies. Successful preclinical efficacy studies with organoids generated from human adult stem cells (ASCs) or PSCs have led to several exciting programs aimed at therapeutic uses.

For instance, Tokyo Medical and Dental University (TMDU) in Japan plans to conduct a first-inhuman trial of intestinal organoids for treatment against inflammatory bowel disease. In February 2022, TMDU developed a protocol to transplant 3D cellular structures that could regenerate damaged intestine. Currently, only one institution is geared toward PSC-derived organoid transplantation. The vascularized liver bud organoid transplantation initiative at the Yokohama City University (YCU) Advanced Medical Research Center was established to treat pediatric metabolic liver disease.

The market players in the country are focusing on organic and inorganic strategies for business development. In March 2019, Yamaha Motor Co., Ltd. entered into a collaborative research project with Hubrecht Organoid Technology (HUB, the Netherlands), a leading organoid research center. The collaboration aims to accelerate the development of technology and jointly analyze business opportunities in this field of research. Similarly, in August 2022, Cincinnati Children's and the RIKEN Center for Biosystems Dynamics Research developed progenitor cells needed to build vital connective tissues for esophagi, livers, stomachs, and lung organoids. Thus, such strategies by the players based in Japan are expected to support the growth of the organoids market in the country over the forecast period.

Leading Key Players:

STEMCELL Technologies Inc; Cellesce Ltd; Hubrecht Organoid Technology; Definigen; Organoid Therapeutics; PeproTech, Inc; Thermo Fisher Scientific Inc; Corning Inc; Merck KGaA, and InSphero. are among the key companies operating in the organoids market.

Companies operating in the organoids market adopt various organic and inorganic strategies. Organic strategies mainly include product launches and product approvals. Acquisitions, collaborations, and partnerships are among the inorganic growth strategies witnessed in the organoids market. These growth strategies allow the market players to expand their businesses and enhance their geographic presence, thereby contributing to the overall organoids market growth. Further, acquisition and partnership strategies help them strengthen their customer base and expand their product portfolios.

Based on source, the organoids market is segmented into pluripotent stem cells and organ-specific adult stem cells. The pluripotent stem cells segment held the larger share of the market in 2022 and is anticipated to register the higher CAGR in the market during the forecast period. Cells that can self-renew by dividing and developing into three primary groups of cells are known as pluripotent stem cells. The three primary groups of cells formed by the pluripotent cells make up a human body, including ectoderm (skin and nervous system) and endoderm (gastrointestinal and respiratory tracts, endocrine glands, liver, and pancreas). Induced pluripotent stem cells (iPSCs) are perceived as an essential resource for regenerative medicine to replace diseased or damaged tissues. iPSCs have numerous biomedical applications in fundamental research, drug screening, toxicological studies, disease modeling, and cell therapy.

These cells can be potentially used in cell replacement therapy to treat patients with cellular diseases. Thus, they are widely used for developing an organoid in vitro. In addition, pluripotent cells are used in biobanking to preserve patient-derived stem cells in various applications, which can be used in research and therapeutics. In November 2017, Cincinnati Children's scientists launched the Center for Stem Cell and Organoid Medicine (CuSTOM), which uses pluripotent stem cells to mimic organoids.

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