Chromatography Resin Market worth $4.1 billion by 2028 | Key players Avantor Performance Materials, Bio-Rad Laboratories, Danaher Corp, Merck KGaA, Tosoh Corp

According to recent market research the "Chromatography Resin Market by type (Natural, Synthetic, Inorganic Media), Technique (Ion Exchange, Affinity, Hydrophobic Interaction, Size Exclusion, Mixed Mode), Application (Pharmaceutical & Biotechnology, FnB), Region - Global Forecasts to 2028", size is projected to reach USD 4.1 billion by 2028 from USD 2.8 billion in 2023, at a CAGR of 8.2%.

The rising demand for therapeutic antibodies is the main driver behind the growth in the industry. Major pharmaceutical companies are actively engaged in the research and development of therapeutic antibodies. One crucial step in purifying monoclonal antibodies involves the removal of anionic impurities like nucleic acids and endotoxins using anion exchange chromatography. Therefore, the crucial role of chromatography techniques in the advancement of monoclonal antibodies is anticipated to propel the chromatography resin market.

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Chromatography techniques employ natural polymers obtained from living cells, such as plant and bacteria cells. Commonly used natural polymer resins in chromatography applications include agarose, cellulose, and dextran. Chitosan is also utilized as a resin in certain ion chromatography applications. These natural polymeric resins are primarily composed of polysaccharides. The significant advantage of these natural polymers lies in their hydrophilic nature, which stems from the abundance of hydroxyl groups in their structure. These characteristics contribute to the increasing demand for chromatography resin made from natural polymers.

In 2022, IEX chromatography emerged as the leading technique in the global market for chromatography resin, accounting for the highest volume share. Ion exchange chromatography involves the separation of molecules through reversible ionic interactions between the analyte molecules and the stationary resin, which possesses an opposite charge. Usually, the stationary resin consists of a cross-linked polymer matrix, such as agarose, to which a functional group is attached. The significant growth of IEX chromatography, primarily driven by the pharmaceutical sector, contributed to its dominant position in terms of volume share.

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The chromatography resin market size is projected to reach USD 4.1 billion by 2028 from USD 2.8 billion in 2023, at a CAGR of 8.2%. Increasing pharmaceutical and biopharmaceutical R&D activities are projected to drive the demand for chromatography resins market. However, the lack of enough trained experts is limiting the growth of the market. In contrast, the growing need for disposable pre-packed columns has created opportunities for manufacturers.

Bio-Rad Laboratories Inc. (US), Merck KGaA (Germany), Danaher Corporation (US), Tosoh Corporation (Japan), Bio-Works Technologies AB (Sweden), Avantor Performance Materials, Inc. (US), Mitsubishi Chemical Corporation (Japan), among others are the major players in this market.

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Bio-Rad Laboratories, Inc. is a multinational manufacturer and worldwide distributor of life science research and clinical diagnostics products. Life science, clinical diagnostics, and others are the three reportable business segments through which it conducts its business activities. Chromatography resins are offered by the business through its life science division. Through subsidiaries with an emphasis on sales, customer support, and product distribution, the company has direct distribution channels in over 35 countries outside of the US. Distributors and agents in some regions outside and inside of these 35 countries, such as North America, South America, Latin America, Europe, and Asia Pacific, improve sales efforts. The acquisition of Celsee, Inc., a provider of tools and supplies for the isolation, detection, and analysis of single cells, was announced by the company in April 2020. It is expected that Celsee's innovative goods and technologies will increase Bio-Rad's presence in the quickly expanding fields of precision medicine and single-cell analysis, both of which provide a better understanding of disease, diagnosis, and treatment.

The Danaher Corporation is a multinational conglomerate with headquarters in the US that develops, produces, and sells professional, medical, industrial, and commercial goods and services. The three reportable segments that Danaher Corporation uses to run its operations are life sciences, diagnostics, and environmental & applied solutions. Through Cytiva, a recently acquired independent business, Danaher provides chromatography resins. The company has operations in 40 countries and territories, including the Middle East, North and Latin America, Asia, and Europe. In order to accelerate the ramp-up of production, Solis BioDyne turned to Danaher in April 2021. Solis BioDyne is a manufacturer of molecular biology applications, including tools for analyzing human DNA, and as such, is a participant in COVID-19 testing. At the Testa Center in Uppsala, Sweden, Solis BioDyne placed its newfound manufacturing skills into effect and helped Danaher grow its affinity chromatography resin product line.

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