Press release
Lebers Hereditary Optic Neuropathy Market is Expected to Show a Healthy Growth Rate During the Study Period (2019-2032)| Key Companies-GenSight Biologics, Mitotech
Lebers Hereditary Optic Neuropathy Market
Download Sample Report to know more
https://www.delveinsight.com/sample-request/lebers-hereditary-optic-neuropathy-lhon-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Lebers Hereditary Optic Neuropathy Overview
Leber hereditary optic neuropathy (LHON) is a rare mitochondrial disorder that typically presents in young males with progressive visual loss due to optic neuropathy. LHON was the first disease to be associated with mitochondrial DNA point mutations and is, therefore, maternally inherited.
Leber Hereditary Optic Neuropathy is transmitted only through the mother, as it is primarily due to mutations in the mitochondrial (not nuclear) genome, and only the egg contributes mitochondria to the embryo. LHON is usually due to one of three pathogenic mitochondrial DNA (mtDNA) point mutations.
Click here to learn more about the Lebers Hereditary Optic Neuropathy Market Landscape @https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Key Highlight from Leber Hereditary Optic Neuropathy Market Report
In Northern European populations about one in 9,000 people carries one of the three primary Leber Hereditary Optic Neuropathy mutations. There is a prevalence of between 1:30,000 to 1:50,000 in Europe.
The Leber Hereditary Optic Neuropathy mutations ND4 G11778A mutation is the primary mutation in most of the world, with 70% of Northern European cases and 90% of Asian cases. Due to a Founder effect, the LHON ND6 T14484C mutation accounts for 86% of LHON cases in Quebec, Canada.
More than 50% of males with a mutation and more than 85% of females with a mutation never experience vision loss or related medical problems. The particular mutation type may predict the likelihood of penetrance, severity of illness, and probability of vision recovery in the affected. As a rule of thumb, a woman who harbors a homoplasmic primary LHON mutation has a ~40% risk of having an affected son and a ~10% risk of having an affected daughter. Additional factors may determine whether a person develops the signs and symptoms of this disorder. Environmental factors such as smoking and alcohol use may be involved, though studies of these factors have produced conflicting results. Researchers are also investigating whether changes in additional genes, particularly genes on the X chromosome, contribute to the development of signs and symptoms. The degree of heteroplasmy, the percentage of mitochondria that have mutant alleles, may play a role.
Patterns of mitochondrial alleles called haplogroups may also affect the expression of mutations.
Learn more about the treatment market for Lebers Hereditary Optic Neuropathy
https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
The Report Covers the Lebers Hereditary Optic Neuropathy Epidemiology Segmented by:
Lebers Hereditary Optic Neuropathy prevalent cases
Lebers Hereditary Optic Neuropathy incident cases
Lebers Hereditary Optic Neuropathy treatment cases
Lebers Hereditary Optic Neuropathy diagnosed cases
Lebers Hereditary Optic Neuropathy Drug Profile and Companies Covered
GenSight Biologics: EPI-743
Neurophth Therapeutics: Idebenone
Mitotech: Curcumin
Stealth BioTherapeutics: Idebenone
Fortify Therapeutics: rAAV2-ND4
Neuroptika: KH176
And many others.
Learn more about the Key Companies and Emerging Therapies in the Lebers Hereditary Optic Neuropathy Market @ https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Table of Contents
Key Insights
Kaposi's Sarcoma Introduction
Executive Summary of Lebers Hereditary Optic Neuropathy
Disease Background and Overview
Lebers Hereditary Optic Neuropathy Epidemiology and patient population
Kaposi's Sarcoma Emerging Therapies
Kaposi Sarcoma Market Outlook
Kaposi Sarcoma Market Access and Reimbursement of Therapies
Kaposi Sarcoma Market Drivers
Kaposi Sarcoma Market Barriers
Appendix
Kaposi's Sarcoma Report Methodology
DelveInsight Capabilities
Disclaimer
Learn about the detailed offerings of the Lebers Hereditary Optic Neuropathy Market Outlook report @ https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Related Reports
Lebers Hereditary Optic Neuropathy Epidemiology Forecast
https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-epidemiology-forecast?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Lebers Hereditary Optic Neuropathy Pipeline Forecast
https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Trending Reports By DelveInsight:
Functional Constipation Market
https://www.delveinsight.com/report-store/chronic-constipation-market
Lebers Hereditary Optic Neuropathy Lhon Market https://www.delveinsight.com/report-store/lebers-hereditary-optic-neuropathy-lhon-market
Gastric Neuroendocrine Tumors Market
https://www.delveinsight.com/report-store/gastric-neuroendocrine-tumors-market
Immune Thrombocytopenic Purpura Market
https://www.delveinsight.com/report-store/immune-thrombocytopenia-itp-market
Visceral Pain Associated With GI Disorders Market
https://www.delveinsight.com/report-store/visceral-pain-associated-with-gi-disorders-market
Bullous Pemphigoid Market
https://www.delveinsight.com/report-store/bullous-pemphigoid-market
Cyclin-dependent Kinase-like 5 Deficiency Disorder Market https://www.delveinsight.com/infographics/cyclin-dependent-kinase-like-5-cdkl5-deficiency-disorder-market
Myocarditis Market
https://www.delveinsight.com/report-store/myocarditis-market
Recurrent Blood Clots Market
https://www.delveinsight.com/report-store/recurrent-blood-clots-thrombophilia-market
Zollinger-ellison Syndrome Market
https://www.delveinsight.com/report-store/zollinger-ellison-syndrome-market
Age-related Hearing Loss Medical Device Market
https://www.delveinsight.com/blog/age-related-hearing-loss-device-market
Heart Sounds Sensors Market
https://www.delveinsight.com/report-store/heart-sounds-sensors-electronic-stethoscope-market
Hypoplastic Left Heart Syndrome Hlhs Market
https://www.delveinsight.com/report-store/hypoplastic-left-heart-syndrome-market
Infectious Arthritis/Septic Arthritis Market
https://www.delveinsight.com/report-store/infectious-arthritisseptic-arthritis-market
Plasmacytoma Market
https://www.delveinsight.com/report-store/plasmacytoma-market
Agoraphobia Market
https://www.delveinsight.com/report-store/agoraphobia-market
Clinically Isolated Syndrome CIS Market
https://www.delveinsight.com/report-store/clinically-isolated-syndrome-cis-market
Fucosidosis Market
https://www.delveinsight.com/report-store/fucosidosis-market
Major Depressive Disorder Market
https://www.delveinsight.com/report-store/major-depressive-disorder-market
Neuronal Ceroid-lipofuscinoses Market
https://www.delveinsight.com/report-store/neuronal-ceroid-lipofuscinoses-cln1-disease-market
Orthotic Devices Market
https://www.delveinsight.com/report-store/orthotic-devices-market
DelveInsight Business Research LLP
Kaul
info@delveinsight.com
https://www.delveinsight.com
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
This release was published on openPR.
Permanent link to this press release:
Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.
You can edit or delete your press release Lebers Hereditary Optic Neuropathy Market is Expected to Show a Healthy Growth Rate During the Study Period (2019-2032)| Key Companies-GenSight Biologics, Mitotech here
News-ID: 3156962 • Views: …
More Releases from DelveInsight Business Research LLP
Genital Warts Pipeline Insights Report 2025 | DelveInsight
DelveInsight's, "Genital Warts Pipeline Insight 2025" report provides comprehensive insights about 30+ companies and 30+ pipeline drugs in Genital Warts pipeline landscape. It covers the Genital Warts pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore the comprehensive insights by DelveInsight and stay ahead…
Traumatic Brain Injury Pipeline Drugs Report 2025 | DelveInsight
DelveInsight's "Traumatic Brain Injury Pipeline Insight 2025" report provides comprehensive insights about 20+ companies and 22+ pipeline drugs in Tthe raumatic Brain Injury pipeline landscape. It covers the Traumatic Brain Injury pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Traumatic Brain Injury pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore…
Bone Metastasis Pipeline Assessment Report 2025 | DelveInsight
DelveInsight's, "Bone Metastases Pipeline Insight, 2025," report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Bone Metastases pipeline landscape. It covers the Bone Metastasis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Bone Metastasis pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Explore the comprehensive insights by DelveInsight…
Acquired Immunodeficiency Syndrome Treatment Market Size Report 2032 | DelveInsi …
DelveInsight's "Acquired Immunodeficiency Syndrome Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Acquired Immunodeficiency Syndrome, historical and forecasted epidemiology as well as the Acquired Immunodeficiency Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
To Know in detail about the Acquired Immunodeficiency Syndrome market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Acquired Immunodeficiency Syndrome Market…
More Releases for Leber
Leber Hereditary Optic Neuropathy Treatment Market
Introduction
Leber Hereditary Optic Neuropathy (LHON) is a genetic condition that leads to severe vision loss, primarily affecting young adults. This disorder is caused by mutations in mitochondrial DNA, which impairs the function of retinal ganglion cells. As awareness of LHON has grown, so too has the focus on its treatment options. The LHON treatment market is evolving rapidly, driven by advancements in genetic therapies, pharmaceuticals, and supportive care strategies. This…
Europe Leber Congenital Amaurosis Market 2023 - Growth, Trends, Market Size
The Europe Leber Congenital Amaurosis Market 2023 Report makes available the current and forthcoming technical and financial details of the industry. It is one of the most comprehensive and important additions to the Prudent Markets archive of market research studies. It offers detailed research and analysis of key aspects of the global Europe Leber Congenital Amaurosis market. This report explores all the key factors affecting the growth of the global…
MEA Leber Congenital Amaurosis Market Size, Share, Industry, Forecast to 2029
The MEA Leber Congenital Amaurosis Market 2023 Report makes available the current and forthcoming technical and financial details of the industry. It is one of the most comprehensive and important additions to the Prudent Markets archive of market research studies. It offers detailed research and analysis of key aspects of the global MEA Leber Congenital Amaurosis market. This report explores all the key factors affecting the growth of the global…
Leber Congenital Amaurosis Market To Reach USD 89.84 Million by 2029
To elaborate the studies and estimations involved in the supreme Leber Congenital Amaurosis market report, a method of standard market research analysis which is SWOT analysis is put forth. This market report opens the door to acquire knowledge about the Healthcare industry which explains what market definition, classifications, applications, engagements and market trends are. The report makes it effortless to identify the types of consumers, their response and views about…
Leber Congenital Amaurosis Market by Players and Application 2024
Leber Congenital Amaurosis Market: Overview
Leber congenital amaurosis (LCA) is a disorder of eye mainly affects the retina. Retina is the specific tissue at the back of the eye responsible for detection of light and color. People, primarily babies suffering with this disorder have severe visual impairment from the first year of life. The visual impairment because of this disorder likely to be stable for the rest of the life, whereas…
Leber Congenital Amaurosis - Pipeline Review, H1 2017
ReportsWorldwide has announced the addition of a new report title Leber Congenital Amaurosis - Pipeline Review, H1 2017 to its growing collection of premium market research reports.
Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Leber Congenital Amaurosis - Pipeline Review, H1 2017, provides an overview of the Leber Congenital Amaurosis (Genetic Disorders) pipeline landscape.
Leber congenital amaurosis is an eye disorder that primarily affects the retina, which is the…
