Press release
Methylmalonic Acidemia Market is Expected to Show a Healthy Growth Rate During the Study Period (2019-2032)| Key Companies- LogicBio Therapeutics, Inc, ModernaTX, Inc.
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Methylmalonic Acidemia Overview
Methylmalonic Acidemia is an autosomal recessive disorder of amino acid metabolism, involving a defect in the conversion of methyl malonyl-coenzyme A (CoA) to succinyl-CoA. Patients typically present at the age of 1 month to 1 year with neurologic manifestations, such as seizure, encephalopathy, and stroke.
Methylmalonic acidemia stems from several genotypes all forms of the disorder usually diagnosed in the early neonatal period, presenting progressive encephalopathy, and secondary hyperammonemia. The disorder can result in death if undiagnosed or left untreated. It is estimated that this disorder has a frequency of 1 in 48,000 births, though the high mortality rate in diagnosed cases makes exact determination difficult. Methylmalonic acidemias are found with an equal frequency across ethnic boundaries.
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Key Highlights from Methylmalonic Acidemia Market Report
Key Companies working in Methylamalonic Acidmia include
LogicBio Therapeutics
ModernaTX, Inc.
and many others
Key Therapies included in the Methylmalonic Acidima market includes
hLB-001
mRNA-3705
and many others.
Methylmalonic AcidemiaTreatment Market
Treatment for all forms of this condition primarily relies on a low-protein diet, and depending on what variant of the disorder the individual suffers from, various dietary supplements. All variants respond to the levo isomer of carnitine as the improper breakdown of the affected substances results in sufferers developing a carnitine deficiency. The carnitine also assists in the removal of acyl-CoA, the buildup of which is common in low-protein diets by converting it into acyl-carnitine which can be excreted in the urine. Some forms of methylmalonyl acidemia are responsive to cobalamin although cyanocobalamin supplements could prove detrimental to some forms. If the individual proves responsive to both cobalamin and carnitine supplements, then it may be possible for them to ingest substances that include small amounts of the problematic amino acids isoleucine, threonine, methionine, and valine without causing an attack.
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The Report Covers the Methylmalonic Acidemia Epidemiology Segmented by:
Methylmalonic Acidemia prevalent cases
Methylmalonic Acidemia Incident Cases
Methylmalonic Acidemia treatment cases
Methylmalonic Acidemia diagnosed cases
Methylmalonic Acidemia Dug Profile and Companies Covered
Moderna Tx- mRNA-3705
Logic Bio Therapeutics- hLB-001
HemoShear Therapeutics- mRNA-3705
And many others.
Learn more about the Key Companies and Emerging Therapies in the Methylmalonic Acidemia Market @https://www.delveinsight.com/report-store/methylmalonic-acidemia-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=dpr
Table of Contents
Key Insights
Methylmalonic Acidemia Introduction
Executive Summary of Methylmalonic Acidemia
Disease Background and Overview
Methylmalonic Acidemia Epidemiology and patient population
Methylmalonic Acidemia Emerging Therapies
Methylmalonic Acidemia Market Outlook
Methylmalonic Acidemia Market Access and Reimbursement of Therapies
Methylmalonic Acidemia Market Drivers
Methylmalonic Acidemia Market Barriers
Appendix
Methylmalonic Acidemia Report Methodology
DelveInsight Capabilities
Disclaimer
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Adya Kaul
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DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.
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