Press release
Alagille Syndrome Market to Witness Upsurge in Growth During the Forecast Period (2023-2032), Examine DelveInsight | Key Companies - Mirum Pharma (Maralixibat), Albireo (Odevixibat), Lumena Pharmaceuticals
As per DelveInsight, the Alagille Syndrome Market is anticipated to evolve immensely in the coming years owing to the increasing awareness, advancements in diagnostic technologies, and the introduction of novel treatment options for the condition.DelveInsight's "Alagille Syndrome Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Alagille Syndrome Market Size and Share in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).
The market report covers emerging drugs, treatment practices, market share of individual Alagille Syndrome therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Alagille Syndrome treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of opportunities and assess the underlying potential of the market.
Alagille Syndrome: An Overview
Alagille Syndrome (ALGS) is a multisystem autosomal dominant disorder with a wide variety of clinical manifestations. It is also known as arteriohepatic dysplasia, Alagille-Watson syndrome, Watson-Miller syndrome, or syndromic bile duct paucity.
The clinical manifestations are variable, even within the same family, and commonly include hepatic (cholestasis, characterized by bile duct paucity on liver biopsy), cardiac (primarily involving the pulmonary arteries), renal skeletal (butterfly vertebrae), ophthalmologic (posterior embryotoxon), and facial abnormalities. It can range from a subclinical presentation to a life-threatening condition, with a mortality rate of up to 10%.
As per NORD, ALGS is a rare genetic disorder that can affect multiple organ systems of the body including the liver, heart, skeleton, eyes, and kidneys. The specific symptoms and severity of Alagille syndrome can vary greatly from one person to another, even within the same family.
Alagille Syndrome Market Key Facts
• As per the estimates by DelveInsight, the total cases of Alagille syndrome in the 7MM were around 18,000 cases in 2022.
• In 2022, among EU4 and the UK, Germany accounted for the highest number of cases, followed by France, according to estimates by DelveInsight.
• According to Diaz et al. (2019), it is estimated that the prevalence of Alagille syndrome varies from 1:30,000 to 1:100,000.
• In 2022, there was about a 4:3 ratio of males and females diagnosed with ALGS in the United States. Assessments, as per DelveInsight's analysts, show that the overall prevalence of gender cases of ALGS will increase in the coming years by 2032.
• Companies such as Ipsen, Takeda, and others have emerged as key players in the market, taking the lead in developing their respective assets for the treatment of Alagille Syndrome.
• According to the Orphanet (2023), the prevalence of Alagille Syndrome has been estimated to be approximately 1 in 70,000.
• According to Diaz-Frias and Kondamudi (2022), It is estimated that the prevalence of Alagille Syndrome varies from 1:30,000 to 1:100,000.
Discover How Alagille Syndrome Market Will Grow by 2032:
https://www.delveinsight.com/report-store/alagille-syndrome-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rpr
Alagille Syndrome Market
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Alagille Syndrome therapies in the market. It also provides a detailed assessment of the Alagille Syndrome market drivers & barriers, unmet needs, and emerging technologies.
The report gives complete detail of the market trend for each marketed Alagille Syndrome drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MOA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Alagille Syndrome Epidemiology
The epidemiology section covers detailed insights into the historical, and current Alagille Syndrome patient pool and forecasted epidemiology trends for every seven major countries (7MM) from 2019 to 2032.
The Report Covers the Alagille Syndrome Epidemiology Segmented as -
• Total Prevalent Cases of Alagille Syndrome (ALGS) in the 7MM (2019-2032)
• Gender-Specific Cases of Alagille Syndrome (ALGS) in the 7MM (2019-2032)
• Diagnosed Cases of Alagille Syndrome (ALGS) in the 7MM (2019-2032)
• Age-Specific Cases of Alagille Syndrome (ALGS) in the 7MM (2019-2032)
Get Key Insights Into the Evolving Alagille Syndrome Epidemiology Trends @
https://www.delveinsight.com/report-store/alagille-syndrome-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rpr
Alagille Syndrome Drugs Uptake and Pipeline Development Activities
The drugs' uptake section focuses on the rate of uptake of the potential drugs recently launched in the Alagille Syndrome market or expected to be launched during the study period. The analysis covers the market share by Alagille Syndrome drugs, patient uptake by therapies, and sales of each drug.
The report's drugs uptake section helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs. It allows the comparison of the drugs based on market share and size, which again will be helpful in investigating factors important in understanding the market dynamics and in making financial and regulatory decisions.
The report also covers the Alagille Syndrome Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
Explore More About Ongoing Pipeline Development Activities @
https://www.delveinsight.com/sample-request/alagille-syndrome-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rpr
Alagille Syndrome Therapeutics Assessment
Several major pharma and biotech companies are developing therapies for Alagille Syndrome. Currently, Mirum Pharmaceuticals is leading the therapeutics market with its Alagille Syndrome drug candidates in the most advanced stage of clinical development.
Leading Companies in the Alagille Syndrome Therapeutics Market Include
• Mirum Pharmaceuticals, Inc.
• Lumena Pharmaceuticals
• Albireo
And Many Others
Emerging and Marketed Alagille Syndrome Therapies Covered in the Report Include
• Maralixibat: Mirum Pharma
• Odevixibat: Albireo
And Many More
Learn More About the Emerging Therapies & Key Companies in the Alagille Syndrome Therapeutics Market:
https://www.delveinsight.com/sample-request/alagille-syndrome-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=rpr
Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Alagille Syndrome Competitive Intelligence Analysis
4. Alagille Syndrome Market Overview at a Glance
5. Alagille Syndrome Background and Overview
6. Alagille Syndrome Patient Journey
7. Alagille Syndrome Epidemiology and Patient Population
8. Alagille Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Alagille Syndrome Unmet Needs
10. Key Endpoints of Alagille Syndrome Treatment
11. Alagille Syndrome Marketed Products
12. Alagille Syndrome Emerging Therapies
13. Alagille Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Alagille Syndrome Market Outlook (7 major markets)
16. Alagille Syndrome Access and Reimbursement Overview
17. KOL Views on the Alagille Syndrome Market.
18. Alagille Syndrome Market Drivers
19. Alagille Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.
Download the Sample PDF to Get Detailed Insights About the Report's Offerings @
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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.
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