Press release
Argininosuccinic Aciduria Market to Witness Growth by 2032, Estimates DelveInsight | Companies- Horizon Therapeutics, Acer Therapeutics, Evox Therapeutics
DelveInsight's "Argininosuccinic Aciduria Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of Argininosuccinic Aciduria, historical and forecasted epidemiology as well as the Argininosuccinic Aciduria market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.The Argininosuccinic Aciduria market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Argininosuccinic Aciduria market size from 2019 to 2032, segmented by seven major markets. The Report also covers current Argininosuccinic Aciduria treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Argininosuccinic Aciduria market.
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Argininosuccinic Aciduria Overview
Argininosuccinic Aciduria is an inherited disorder that causes ammonia to accumulate in the blood. Ammonia, which is formed when proteins are broken down in the body, is toxic if the levels become too high. The nervous system is especially sensitive to the effects of excess ammonia. Argininosuccinic Aciduria usually becomes evident in the first few days of life. An infant with Argininosuccinic Aciduria may be lacking in energy (lethargic) or unwilling to eat, and have a poorly controlled breathing rate or body temperature. Some babies with this disorder experience seizures or unusual body movements, or go into a coma. Complications from Argininosuccinic Aciduria may include developmental delay and intellectual disability. Progressive liver damage, high blood pressure (hypertension), skin lesions, and brittle hair may also be seen.
Symptoms
The severity and specific symptoms of Argininosuccinic Aciduria varies from one person to another. A severe form of the disorder, which is characterized by a complete or near complete lack of the ASL enzyme, occurs shortly after birth (neonatal period). A milder form of the disorder, which is characterized by partial lack of the ASL enzyme, affects some individuals later during infancy or childhood or even adulthood (late-onset form). Affected infants may also experience seizures, breathing (respiratory) abnormalities, the accumulation of fluid in the brain (cerebral edema), and an abnormally large liver (hepatomegaly). Less commonly, some individuals develop progressive liver disease and dysfunction such as the buildup of scar tissue (fibrosis) and cirrhosis. In rare instances, chronic kidney (renal) disease has been reported.
Diagnosis
A diagnosis of a urea cycle disorder, such as Argininosuccinic Aciduria, should be considered in any newborn that has an undiagnosed illness characterized by vomiting, progressive lethargy, and irritability. A diagnosis of Argininosuccinic Aciduria can be made through a detailed patient/family history, identification of characteristic findings, and a variety of specialized tests. Blood tests may reveal excessive amounts of ammonia in the blood, which is the main criterion for a diagnosis of urea cycles disorders including Argininosuccinic Aciduria.
Treatment
The treatment of Argininosuccinic Aciduria is aimed at preventing excessive ammonia from being formed or from removing excessive ammonia during a hyperammonemic episode. Long-term therapy combines dietary restrictions and the stimulation of alternative methods of converting and excreting nitrogen from the body (alternative pathways therapy). Dietary restrictions in individuals with Argininosuccinic Aciduria are aimed at limiting the amount of protein intake to avoid the development of excess ammonia.
In 2013, the U.S. Food and Drug Administration (FDA) approved Ravicti (glycerol phenylbutyrate) for the chronic management of urea cycle disorders including Argininosuccinic Aciduria in affected individuals age 2 years and older.
Learn more about Argininosuccinic Aciduria, treatment algorithms in different geographies, and patient journeys. Contact to receive a sample @ https://www.delveinsight.com/report-store/argininosuccinic-aciduria-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Argininosuccinic Aciduria Market
The Argininosuccinic Aciduria market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Argininosuccinic Aciduria market trends by analyzing the impact of current Argininosuccinic Aciduria therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.
This segment gives a thorough detail of the Argininosuccinic Aciduria market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Argininosuccinic Aciduria market data are presented with relevant tables and graphs to give a clear view of the market at first sight.
According to DelveInsight, the Argininosuccinic Aciduria market in 7MM is expected to witness a major change in the study period 2019-2032.
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Argininosuccinic Aciduria Epidemiology
The Argininosuccinic Aciduria epidemiology section provides insights into the historical and current Argininosuccinic Aciduria patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Argininosuccinic Aciduria market report also provides the diagnosed patient pool, trends, and assumptions.
Explore more about Argininosuccinic Aciduria Epidemiology at: https://www.delveinsight.com/report-store/argininosuccinic-aciduria-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Argininosuccinic Aciduria Drugs Uptake
This section focuses on the uptake rate of the potential Argininosuccinic Aciduria drugs recently launched in the Argininosuccinic Aciduria market or expected to be launched in 2019-2032. The analysis covers the Argininosuccinic Aciduria market uptake by drugs, patient uptake by therapies, and sales of each drug.
Argininosuccinic Aciduria Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Argininosuccinic Aciduria market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
Argininosuccinic Aciduria Pipeline Development Activities
The Argininosuccinic Aciduria report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Argininosuccinic Aciduria key players involved in developing targeted therapeutics.
Request for a sample report to understand more about the Argininosuccinic Aciduria pipeline development activities at: https://www.delveinsight.com/sample-request/argininosuccinic-aciduria-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Argininosuccinic Aciduria Therapeutics Assessment
Major key companies such as Horizon Therapeutics, Acer Therapeutics, Evox Therapeutics, and others are working proactively in the Argininosuccinic Aciduria Therapeutics market to develop novel therapies which will drive the Argininosuccinic Aciduria treatment markets in the upcoming years.
Learn more about the emerging therapies & key companies at: https://www.delveinsight.com/report-store/argininosuccinic-aciduria-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Argininosuccinic Aciduria Report Key Insights
1. Argininosuccinic Aciduria Patient Population
2. Argininosuccinic Aciduria Market Size and Trends
3. Key Cross Competition in the Argininosuccinic Aciduria Market
4. Argininosuccinic Aciduria Market Dynamics (Key Drivers and Barriers)
5. Argininosuccinic Aciduria Market Opportunities
6. Argininosuccinic Aciduria Therapeutic Approaches
7. Argininosuccinic Aciduria Pipeline Analysis
8. Argininosuccinic Aciduria Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Argininosuccinic Aciduria Market
Table of Contents
1. Key Insights
2. Executive Summary
3. Argininosuccinic Aciduria Competitive Intelligence Analysis
4. Argininosuccinic Aciduria Market Overview at a Glance
5. Argininosuccinic Aciduria Disease Background and Overview
6. Argininosuccinic Aciduria Patient Journey
7. Argininosuccinic Aciduria Epidemiology and Patient Population
8. Argininosuccinic Aciduria Treatment Algorithm, Current Treatment, and Medical Practices
9. Argininosuccinic Aciduria Unmet Needs
10. Key Endpoints of Argininosuccinic Aciduria Treatment
11. Argininosuccinic Aciduria Marketed Products
12. Argininosuccinic Aciduria Emerging Therapies
13. Argininosuccinic Aciduria Seven Major Market Analysis
14. Attribute Analysis
15. Argininosuccinic Aciduria Market Outlook (7 major markets)
16. Argininosuccinic Aciduria Access and Reimbursement Overview
17. KOL Views on the Argininosuccinic Aciduria Market
18. Argininosuccinic Aciduria Market Drivers
19. Argininosuccinic Aciduria Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
Get the Detailed TOC of the Argininosuccinic Aciduria Market report here: https://www.delveinsight.com/report-store/argininosuccinic-aciduria-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr
Contact Us:
Kritika Rehani
info@delveinsight.com
+1(919)321-6187
www.delveinsight.com
About DelveInsight
DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.
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