Schizophrenia Pipeline, Clinical Trials Assessment, Emerging Drugs, NDA Approvals 2023 (Updated) | Otsuka Pharmaceutical Development & Commercialization, Inc., Gedeon Richter Ltd., Neurocrine Bioscience, Takeda Pharmaceutical Company, and others

DelveInsight's, "Schizophrenia Pipeline Insight 2023," report provides comprehensive insights about 70+ companies and 70+ pipeline drugs in the Schizophrenia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

In the Schizophrenia Pipeline Report, a detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Schizophrenia collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Key Takeaways from the Schizophrenia Pipeline Report
• DelveInsight's Schizophrenia pipeline report depicts a robust space with 70+ active players working to develop 70+ pipeline therapies for Schizophrenia treatment.
• The leading Schizophrenia Companies includes Otsuka Pharmaceutical Development & Commercialization, Inc., Gedeon Richter Ltd., Neurocrine Bioscience, Takeda Pharmaceutical Company, Memory Pharmaceuticals, Hoffmann-La Roche, Neurocrine Biosciences, H. Lundbeck, Organon and Co, Meiji Seika Pharma Co., Ltd., SK Life Science, Inc., Novartis Pharmaceuticals, Vanda Pharmaceuticals, Alkermes, Inc., Solvay Pharmaceuticals, Sumitomo Dainippon Pharma Co., Ltd., Mitsubishi Tanabe Pharma Corporation, SyneuRx International (Taiwan) Corp, BioXcel Therapeutics Inc, Cognitive Research Corporation, Amarex Clinical Research, Forum Pharmaceuticals Inc, Amneal Pharmaceuticals, LLC, Accutest Research Laboratories (I) Pvt. Ltd., Eli Lilly and Company, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Janssen, LP, Delpor, Inc., Cerevel Therapeutics, LLC, Zogenix, Inc., Reviva Pharmaceuticals, Alkermes, Inc., Karuna Therapeutics, and others.
• Promising Schizophrenia Pipeline Therapies include CAD-9303, CVL 231, and others.
• The Schizophrenia companies and academics are working to assess challenges and seek opportunities that could influence Schizophrenia R&D. The Schizophrenia pipeline therapies under development are focused on novel approaches to treat/improve Schizophrenia.

To explore more information on the latest breakthroughs in the Schizophrenia Pipeline treatment landscape of the report, click here @ Schizophrenia Pipeline Outlook- https://www.delveinsight.com/report-store/schizophrenia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Schizophrenia Overview
Schizophrenia causes psychosis and is associated with considerable disability and may affect all areas of life including personal, family, social, educational, and occupational functioning. It is thought that interaction between genes and a range of environmental factors may cause schizophrenia.

Recent Developmental Activities in the Schizophrenia Treatment Landscape
• On April 2023, Otsuka Pharmaceutical Development & Commercialization Inc announced a study of phase 3 clinical trials for Brexpiprazole. To further characterize the long-term safety and tolerability of brexpiprazole in adolescents with schizophrenia.
• On May 2023, Click Therapeutics Inc announced a study of phase 3 clinical trials for Digital Therapeutic Device. This study evaluates the efficacy of two prescription digital therapeutics (PDT) in addition to standard of care (SOC) therapy for the treatment of experiential negative symptoms of schizophrenia in late adolescents and adults.

For further information, refer to the detailed Schizophrenia Unmet Needs, Schizophrenia Market Drivers, and Schizophrenia Market Barriers, click here for Schizophrenia Ongoing Clinical Trial Analysis- https://www.delveinsight.com/sample-request/schizophrenia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Schizophrenia Emerging Drugs Profile

Ulotaront: Otsuka Pharmaceutical
Ulotaront (SEP-363856), one of the first of a new class of CNS-active compounds, is an agonist at trace amine-associated receptor 1 (TAAR1) as well as serotonin 5-HT1A receptors. TAAR1 is a G-protein-coupled receptor expressed in cortical, limbic, and midbrain monoaminergic regions that modulate dopaminergic, serotonergic, and glutamatergic activity. In contrast to first- and second-generation antipsychotics, the efficacy of ulotaront is not mediated by blockade of D2 or 5-HT2A receptors. Ulotaront has demonstrated positive effects in rodent models assessing endophenotypes of schizophrenia, including phencyclidine (PCP)-induced hyperactivity, prepulse inhibition, and PCP-induced deficits in social interaction and cognition. An Open-label Extension Study to Assess the Safety and Tolerability of SEP-363856 in Subjects with Schizophrenia. It's currently in phase III stage of development.

Luvadaxistat: Takeda
Luvadaxistat is a potential first-in-class, investigational, oral, selective inhibitor with a high binding affinity to d-amino acid oxidase (DAAO). It targets glutamate, an abundant neurotransmitter in the brain. In schizophrenia, N-methyl D-aspartate (NMDA) receptor hypofunction on PV+ gamma-aminobutyric acid (GABA) interneurons results in disinhibition of cortical or hippocampal glutamate neurons projecting to the pyramidal neurons. The cortical disturbances account for the negative/cognitive symptoms of schizophrenia, while the downstream subcortical dopamine release manifests as the positive symptoms of the disorder. A Phase II Randomized, Double-Blind, Placebo-Controlled, cross-Over Study to Evaluate Pharmacodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Multiple Oral Doses of TAK-831 in Adult Subjects With Schizophrenia is ongoing.

CY6463: Cyclerion Therapeutics
CY6463 is the first CNS-penetrant sGC stimulator to be developed as a symptomatic and potentially disease-modifying therapy for serious CNS diseases. The nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic guanosine monophosphate (cGMP) signaling pathway is a fundamental mechanism that precisely controls key aspects of physiology throughout the body. Cyclerion Therapeutics has initiated a double-blinded, randomized, placebo-controlled, multiple-ascending-dose Study to Assess the Safety and Pharmacokinetics of CY6463 in Participants with Stable Schizophrenia.

AVP 786: Avanir Pharmaceuticals
Deudextromethorphan (AVP 786) is a combination product of a deuterium-containing analogue of dextromethorphan and an ultra-low dose of quinidine, that is being developed by Avanir Pharmaceuticals (a subsidiary of Otsuka Pharmaceuticals), under a license from Concert Pharmaceuticals, for the treatment of psychiatric and Neurological Indications. Currently it is being evaluated in phase II/III stage of development for the treatment of schizophrenia.

Schizophrenia Pipeline Therapeutics Assessment
There are approx. 70+ key companies which are developing the therapies for Schizophrenia. The companies which have their Schizophrenia drug candidates in the most advanced stage, i.e. phase III include, Otsuka Pharmaceutical.

Request a sample and discover the recent advances in Schizophrenia Ongoing Clinical Trial Analysis and Medications, click here @ Schizophrenia Treatment Landscape- https://www.delveinsight.com/sample-request/schizophrenia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Schizophrenia Pipeline Report
• Coverage- Global
• Schizophrenia Companies- Otsuka Pharmaceutical Development & Commercialization, Inc., Gedeon Richter Ltd., Neurocrine Bioscience, Takeda Pharmaceutical Company, Memory Pharmaceuticals, Hoffmann-La Roche, Neurocrine Biosciences, H. Lundbeck, Organon and Co, Meiji Seika Pharma Co., Ltd., SK Life Science, Inc., Novartis Pharmaceuticals, Vanda Pharmaceuticals, Alkermes, Inc., Solvay Pharmaceuticals, Sumitomo Dainippon Pharma Co., Ltd., Mitsubishi Tanabe Pharma Corporation, SyneuRx International (Taiwan) Corp, BioXcel Therapeutics Inc, Cognitive Research Corporation, Amarex Clinical Research, Forum Pharmaceuticals Inc, Amneal Pharmaceuticals, LLC, Accutest Research Laboratories (I) Pvt. Ltd., Eli Lilly and Company, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Janssen, LP, Delpor, Inc., Cerevel Therapeutics, LLC, Zogenix, Inc., Reviva Pharmaceuticals, Alkermes, Inc., Karuna Therapeutics, and others.
• Schizophrenia Pipeline Therapies- CAD-9303, and CVL 231, and others.
• Schizophrenia Pipeline Segmentation: Product Type, Molecule Type, Route of Administration

Dive deep into rich insights for drugs for Schizophrenia Market Drivers and Schizophrenia Market Barriers, click here @ Schizophrenia Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/schizophrenia-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Schizophrenia: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Schizophrenia - DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. Ulotaront: Otsuka Pharmaceutical
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II/III)
11. Deudextromethorphan: Avanir Pharmaceuticals
12. Drug profiles in the detailed report…..
13. Mid Stage Products (Phase II)
14. Luvadaxistat: Takeda
15. Drug profiles in the detailed report…..
16. Early Stage Products (Phase I/II)
17. SP-624: Sirtsei Pharmaceuticals
18. Drug profiles in the detailed report…..
19. Early Stage Products (Phase I)
20. CY6463: Cyclerion Therapeutics
21. Drug profiles in the detailed report…..
22. Preclinical and Discovery Stage Products
23. Psychiatric disorder therapies : Cardiff University/Takeda
24. Drug profiles in the detailed report…..
25. Inactive Products
26. Schizophrenia Key Companies
27. Schizophrenia Key Products
28. Schizophrenia - Unmet Needs
29. Schizophrenia - Market Drivers and Barriers
30. Schizophrenia - Future Perspectives and Conclusion
31. Schizophrenia Analyst Views
32. Schizophrenia Key Companies
33. Appendix

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