mRNA Vaccines Therapeutics Market Size, Share, Trend, Opportunity Analysis, & Forecast 2023 to 2033

mRNA is a rather versatile technology and offers a number of advantages. mRNA lacks genomic integration and its use results in transient expression of the encoded protein. This favorable safety profile makes mRNA especially attractive for vaccines and gene editing. mRNA is well defined chemically which ensures reproducible manufacturing at high yield, purity and activity. Improvements of lipid nanoparticle formulations as a vehicle for in vivo systemic delivery of mRNA has greatly favored the development of in vivo transfection strategies.

The global mRNA Vaccines & Therapeuticsm market was valued at USD 39596.95 million in 2021 and is expected to reach USD 11868.26 million by the end of 2028, growing at a CAGR of -19.38% between 2022 and 2028. The COVID-19 pandemic and the advantages of mRNA therapeutics, along with related technological advancements, are the core drivers driving the mRNA Vaccines & Therapeutics market.The COVID-19 pandemic has favorably impacted the growth of the global market owing to an increase in the number of COVID-19 patients globally and substantial external financing for the production of mRNA-based COVID-19 vaccines. Furthermore, when new strains of the SARS-COVID-19 virus appeared in many countries around the world, the demand for mRNA vaccines rose sharply due to their effective protection against these strains. Hence, the use of these mRNA-based products is expected to increase during the COVID-19 pandemic and lead to market growth.

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Compared with traditional vaccines, mRNA vaccines have the advantages of high efficacy and low production costs. Compared with traditional vaccines (attenuated, inactivated, recombinant subunit and other vaccines), mRNA vaccines have a simple production process, do not require cell culture or animal-derived substrates, and have fast synthesis and low cost. In terms of mechanism of action, compared with traditional inactivated vaccines, traditional vaccines directly inject antigenic proteins into the human body to cause an immune response. Due to its mature technology and R&D and production experience, the adverse reaction rate is low. mRNA is the injection of mRNA encoding viral antigens into the body, and the corresponding antigens are produced by the body's own cells, thereby activating specific immunity. The process of presenting antigens with inactivated vaccines is one-time, and no new antigens will be added thereafter. The process of antigen presentation of mRNA vaccines is short-lived and sustainable, and the protection efficiency is relatively higher. However, compared with DNA vaccines, which are also nucleic acid vaccines, mRNA vaccines do not need to enter the nucleus to function, there is no risk of integration into the host genome, and they are transiently expressed, and the half-life can be adjusted by modification.

In addition, difficulties in R&D and commercialization, insufficient public awareness of the importance of immunization, and shortcomings of mRNA itself are expected to hinder the development of the market.

Segment by Type, the mRNA Vaccines & Therapeutics can be split into Infectious Disease Vaccines, Other Vaccines, etc. At present, Infectious Disease Vaccines is the most important product and the most important commercial application of mRNA. The infectious disease segment leads the market and captures 100% revenue share in 2021. Rising adoption of mRNA-based vaccines, numerous drug candidates entering clinical trials for various infectious diseases, and the COVID-19 outbreak at the end of 2019 are expected to drive the market over the forecast period.

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In terms of application scenarios, the mRNA Vaccines & Therapeutics market can be divided into two types: Vaccine Production and Pharmaceutical R&D. In 2021, the Vaccine Production type will dominate the market, accounting for 95.97% of the entire market share, while the Pharmaceutical R&D type is only 4.03% .

On basis of geography, the mRNA Vaccines & Therapeuticsm market is segmented into North America, Europe, Japan, China, etc. Europe will dominate the market with a share of over 68.38% in 2021. Availability of substantial research funding, high frequency of RNA-based drugs, and clinical trials drive the European market.

Currently, the main players in the mRNA Vaccines & Therapeuticsm Market include BioNTech, Moderna Therapeutics, Translate Bio, eTheRNA, Tiba Biotechnology. Among them, BioNTech and Moderna Therapeutics have become the absolute leaders of the mRNA Vaccines & Therapeuticsm Market, accounting for 53.18% in 2021 respectively and 44.64% market share.

Global mRNA Vaccines & Therapeutics Market: Market Segmentation Analysis

The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, a decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.

Key Company

BioNTech

Moderna Therapeutics

Translate Bio

eTheRNA

Tiba Biotechnology



Market Segmentation (by Type)

Infectious Disease Vaccines

Other Vaccines

Market Segmentation (by Application)

Vaccine Production

Pharmaceutical R&D

Geographic Segmentation

• North America (USA, Canada, Mexico)

• Europe (Germany, UK, France, Russia, Italy, Rest of Europe)

• Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)

• South America (Brazil, Argentina, Columbia, Rest of South America)

• The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)



Key Benefits of This Market Research:

• Industry drivers, restraints, and opportunities covered in the study

• Neutral perspective on the market performance

• Recent industry trends and developments

• Competitive landscape & strategies of key players

• Potential & niche segments and regions exhibiting promising growth covered

• Historical, current, and projected market size, in terms of value

• In-depth analysis of the mRNA Vaccines & Therapeutics Market

• Overview of the regional outlook of the mRNA Vaccines & Therapeutics Market:



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• Provision of market value (USD Billion) data for each segment and sub-segment

• Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

• Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

• Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled

• Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players

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Chapter Outline

Chapter 1 mainly introduces the statistical scope of the report, market division standards, and market research methods.

Chapter 2 is an executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the mRNA Vaccines & Therapeutics Market and its likely evolution in the short to mid-term, and long term.

Chapter 3 makes a detailed analysis of the Market's Competitive Landscape of the market and provides the market share, capacity, output, price, latest development plan, merger, and acquisition information of the main manufacturers in the market.

Chapter 4 is the analysis of the whole market industrial chain, including the upstream and downstream of the industry, as well as Porter's five forces analysis.

Chapter 5 introduces the latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 6 provides the analysis of various market segments according to product types, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 7 provides the analysis of various market segments according to application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 8 provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.

Chapter 9 introduces the basic situation of the main companies in the market in detail, including product sales revenue, sales volume, price, gross profit margin, market share, product introduction, recent development, etc.

Chapter 10 provides a quantitative analysis of the market size and development potential of each region in the next five years.

Chapter 11 provides a quantitative analysis of the market size and development potential of each market segment (product type and application) in the next five years.

Chapter 12 is the main points and conclusions of the report.

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