Urea Cycle Disorders Treatment Market Is Projected To Reach Around USD 1,650 Million In 2030 Exhibiting A CAGR Of 3.5% In The Forecasted Period

The global urea cycle disorders treatment market size was valued at USD 1,250 million in 2021 and is projected to reach around USD 1,650 million in 2030 exhibiting a CAGR of 3.5% in the forecasted period.

the expanding number of pipeline items and the frequency of urea cycle disorders. industry expansion is predicted to be aided by product approvals, launches, and strategic moves made by key industry participants. Additionally, market players will benefit from research and development studies highlighting the genetic description of urea cycle disorders because they will help them align their product development with market growth. On the other hand, the high price of medicines may be a barrier to this market's expansion.

Treatment for urea cycle diseases has a mediocre level of competition. New players are preparing to enter the market as urea cycle disorders treatment applications increase. The businesses participate in a variety of activities, including joint ventures, partnerships, purchases, mergers, and collaborations. These activities help the market's growth by increasing the impact of the participants in the market for treating urea cycle disorders.

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Key Companies Insights
The market for urea cycle disorders treatment is moderately competitive. With the rising applications of urea cycle disorders treatment, new players are planning to enter the market. The companies are also involved in events like joint ventures, partnerships, acquisitions, mergers, and collaborations. These activities aid in growing the effect of the players in the Urea cycle disorders treatment market, ultimately boosting the market growth. Some of the key companies working in the global Urea cycle disorders treatment market include:
• Bausch Health Companies Inc.
• Recordati Rare Diseases
• Eurocept Pharmaceuticals Holding (Lucane Pharma SA)
• Acer Therapeutics
• Ultragenyx Pharmaceutical
• Aeglea BioTherapeutics
• Arcturus Therapeutics, Inc.
• Orpharma Pty Ltd.
• Selecta Biosciences, Inc.
• Abbott Laboratories
• Mead Johnson & Company, LLC
• Other players
Some of the Recent Developments:
• In February 2022, Relief Therapeutics Holding SA and Acer Therapeutics, were issued a new patent from the United States Patent and Trademark Office (USPTO) for certain claims related to ACER-001 (sodium phenylbutyrate) related to ACER-001's multi-particulate dosage formulation for oral management as a possible treatment for Urea Cycle Disorders (UCDs) and Maple Syrup Urine Disease (MSUD).
• In January 2022, Acer Therapeutics Inc. and Relief Therapeutics Holding SA declared the approval of four ACER-001 abstracts for poster presentations in Orlando, Florida, and in Las Vegas, Nevada.
Segments
By Treatment Type
• Amino Acid Supplements
• Sodium Phenylbutyrate
• Glycerol Phenylbutyrate
• Sodium Benzoate
• Others
By Enzyme Deficiency Type
• Ornithine Transcarbamylas (OTC)
• Argininosuccinate Synthetase (citrullinemia) (AS)
• Arginase (AG)
• Argininosuccinate Lyase (AL)
• Carbamoyl Phosphate Synthase (CPS1)
• N-acetylglutamate Synthase (NAGS)
By Route of Administration
• Oral
• Injectable
By Geography
• North America
o U.S.
o Canada
o Mexico
• Europe
o U.K.
o Germany
o France
o Italy
o Spain
o Russia
• Asia-Pacific
o Japan
o China
o India
o Australia
o South Korea
o ASEAN
• Latin America
o Brazil
o Argentina
o Colombia
• MEA
o South Africa
o Saudi Arabia
o UAE
o Egypt

Region Insights:

Among regions, North America is anticipated to hold leading position in the global urea cycle disorders treatment market during the forecast period, owing to key companies focusing on product launches for the treatment of Urea cycle disorders. For instance, in January 2021, Recordati Rare Diseases Inc. received the U.S. Food and Drug Administration (FDA) sanction for CARBAGLU for handling the acute hyperammonemia.
The primary boosting factors for the growth of the North American urea cycle disorders treatment market are the growing prevalence of urea cycle disorders in the region and the snowballing number of pipeline products. Additionally, increasing product launches and other strategic initiatives such as mergers and acquisitions and partnerships are also anticipated to drive the market's growth.

The United States within North America is estimated to hold a significant share of the market throughout the forecasted period. For example, as per the study published in January 2021, titled "Management of Late Onset Urea Cycle Disorders-A Remaining Challenge for the Intensivist?" The yearly incidence in the United States is 1: 35,000 births which exemplifies 113 new cases each year. Therefore, there is a great burden of UCDs on the United States healthcare system, growing the demand for its diagnostics and therapeutics, hence, boosting the market.

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Recently, nations have faced an enormous threat of COVID-19. As per the World Health Organization (WHO), coronavirus is an infectious disease, and most people diseased with the COVID-19 virus will experience mild to moderate respiratory illness. The occurrence of the COVID-19 pandemic damaged the world economy and the healthcare system. The item "Longitudinal Metabolomics Reveals Ornithine Cycle Dysregulation Correlates with Inflammation and Coagulation in COVID-19 Severe Patients," issued in December 2021, recognized that the ornithine cycle dysregulation is significantly interrelated with swelling and coagulation in severe patients, which may be a possible machinery of COVID-19 pathogenicity. Consequently, the COVID-19 medicines hindered the urea cycle, aiming to a lack of certain enzymes. Therefore, there is a growing demand for its therapeutics, contributing to market growth.

Though, the production of these drugs was hindered owing to the momentary lockdown in the manufacturing plants, dearth of skilled labour, and increasing cases of COVID-19 inside the manufacturing plants, which has led to outages, thus, hampering the market. Hence, the above factors indicate that COVID-19 considerably impacted the market.

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Key Questions Answered in the Report:
1. What will be the development pace of market? What is the growth rate of the global market?
2. Who are the key manufacturers in the market space? Who are the world's leading manufacturers?
3. What are sales, revenue, and price analysis of the top manufacturers of market?
4. Who are the distributors, traders, and dealers of market? What are the key factors driving the Global market?
5. What are the market opportunities and threats faced by the vendors in the industries?
6. What are deals, incomes, and value examinations by types and applications of the market?

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