Ankylosing Spondylitis Market by Drug Class (NSAIDs, TNF Inhibitors and Others), and Distribution Channel (Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy): Global Opportunity Analysis and Industry Forecast, 2023-2033

Introduction
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine and pelvis, leading to stiffness, pain, and reduced mobility. The condition can also affect other joints, such as the shoulders, hips, and knees, as well as organs such as the eyes and heart.

AS is a rare disease, affecting around 0.1% to 1.4% of the global population, according to estimates by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). However, the prevalence varies widely across different populations, with higher rates observed in certain ethnic groups, such as Native Americans and Northern Europeans.

Despite being a rare condition, AS can have a significant impact on patients' quality of life, as well as on the healthcare system as a whole. In recent years, the global ankylosing spondylitis market has witnessed significant growth, driven by advances in diagnosis and treatment, as well as by increasing awareness and education among healthcare professionals and patients.

In this article, we will explore the latest trends and opportunities in the global ankylosing spondylitis market, covering topics such as diagnosis, treatment, and key players in the industry.

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Size of the Global Ankylosing Spondylitis Market
The global ankylosing spondylitis market was valued at USD 4.6 billion in 2020 and is expected to reach USD 6.8 billion by 2026, growing at a CAGR of 6.2% during the forecast period.

North America currently dominates the global ankylosing spondylitis market, accounting for the largest share of the market in terms of revenue. This is primarily due to the high prevalence of the disease in the region, as well as the availability of advanced healthcare facilities and a well-established healthcare infrastructure. Europe is the second-largest market for ankylosing spondylitis, followed by the Asia Pacific region.

Key Companies Insights
The market for ankylosing spondylitis is moderately competitive. With the rising applications of Ankylosing spondylitis, new players are considering to enter the market. The companies are also involved in activities like joint ventures, acquisitions, partnerships, mergers, and collaborations. These activities aid in growing the effect of the players in the ankylosing spondylitis market, ultimately boosting the market growth.

Some of the key companies working in the global ankylosing spondylitis market include:
• Amgen Inc.
• AbbVie Inc.
• Pfizer Inc.
• Novartis AG
• Bristol-Myers Squibb Company
• CELGENE CORPORATION
• Eli Lilly and Company
• Cipla Inc.
• Emcure Pharmaceuticals
• Torrent Pharmaceuticals Ltd.
• UCB S.A.
• Suzhou Zelgen Biopharmaceuticals Co., Ltd.
• HENGRUI USA
• Johnson & Johnson Services, Inc.
• Other players

Some of the Recent Developments:
• In August 2021, Inmagene Biopharmaceuticals and Affibody AB were working in a partnership, declared the successful medicating of the first patient in the global ASPIRE phase 2 trial evaluating izokibep (IMG-020 or ABY-035) for treating ankylosing spondylitis (AS).
• In August 2019, Eli Lilly and Company received the approval of Taltz (ixekizumab) by the U.S. Food and Drug Administration (FDA). It is approved for active ankylosing spondylitis, as an injection of 80 mg/mL, firmly for adult patients with this disorder. It can be managed either as monotherapy or as a mixture treatment with other conservative therapies such as DMARDs or NSAIDs.

Segments
By Drug Type
• Cosentyx
• Humira
• Simponi
• Remicade
• Enbrel
• Cimzia
• Others

By Route of Administration
• Oral
• Parenteral
By Distribution Channel
• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies

By Geography
• North America
o U.S.
o Canada
o Mexico
• Europe
o U.K.
o Germany
o France
o Italy
o Spain
o Russia
• Asia-Pacific
o Japan
o China
o India
o Australia
o South Korea
o ASEAN
• Latin America
o Brazil
o Argentina
o Colombia
• MEA
o South Africa
o Saudi Arabia
o UAE
o Egypt

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Diagnosis of Ankylosing Spondylitis
Early diagnosis is crucial in managing AS and preventing long-term complications. However, the diagnosis can be challenging, as the symptoms can be similar to other conditions such as mechanical back pain, sciatica, or rheumatoid arthritis.

To diagnose AS, healthcare professionals typically rely on a combination of clinical assessment, blood tests, and imaging studies such as X-rays or MRI scans. One of the most widely used diagnostic tools is the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), which measures disease activity based on patient-reported symptoms such as pain, stiffness, and fatigue.

In recent years, there has been a growing interest in using biomarkers to aid in the diagnosis of AS. Biomarkers are measurable substances in the body that can indicate the presence or severity of a disease. For example, researchers have identified several biomarkers that are associated with inflammation and tissue damage in AS, such as C-reactive protein (CRP), interleukin-17 (IL-17), and tumor necrosis factor-alpha (TNF-alpha).

By using biomarkers, healthcare professionals may be able to diagnose AS earlier and with greater accuracy, leading to better outcomes for patients.

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